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View Structure Prediction Details

Protein: CG7849-PB
Organism: Drosophila melanogaster
Length: 317 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG7849-PB.

Description E-value Query
Range
Subject
Range
TRUB_RUEPO - tRNA pseudouridine synthase B OS=Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) GN=truB ...
TRUB_SILPO - tRNA pseudouridine synthase B OS=Silicibacter pomeroyi GN=truB PE=3 SV=1
274.0 [0..61] [317..1]

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Predicted Domain #1
Region A:
Residues: [1-317]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALTKVYDAA TVFKHMNGIL NVYKPSGMKV KHVRNAILSN ICKGLNEMEQ RKPRKLQENI  60
   61 SLLGTGTAAD HVLHNIGEQT DLSDHLLSTG PRYLPRDLIC TTVSSLGDHT SGVLLFGINR 120
  121 GAGQSSSIRK NRPVRVYHLI GHLGIATENN LPDSRVIMRS NHRHVSADRI SSLAASMQAS 180
  181 HQRKMFELCG VDLQTQEAYE LACRGLLRPA DDSQPVVYGI KLIHFDRPHF TLELHAINET 240
  241 QEYLATLVHD MALDLRTVAH CSQLRCVRHA HFDVTDSLLR HAWHLPGIIK NLRQQRDILR 300
  301 AHPQLLRQQR VELRATD

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Detection Method: PSI-BLAST
Confidence: 70.69897
Match: 1r3fA
Description: Crystal Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA-protein Recognition Through a Combination of Rigid Docking and Induced Fit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.49175104308599 bayes_pls_golite062009
isomerase activity 0.87098451300632 bayes_pls_golite062009
intramolecular transferase activity 0.86450504855635 bayes_pls_golite062009
pseudouridine synthase activity 0.86297783328106 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle