Protein Overview: sxc-PB, sxc-PC, ...

General Information:
Name(s) found:	sxc-PC / FBpp0085422 [FlyBase] sxc-PA / FBpp0085421 [FlyBase] sxc-PB / FBpp0085420 [FlyBase]
Description(s) found: Found 51 descriptions. SHOW ALL	The gene super sex combs is referred to in FlyBase by the symbol Dmel\sxc (CG10392, FBgn0261403). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:1194756..1216986. It has the cytological map location 41C1-41C2. There is experimental evidence that it has the molecular function</span>: acetylglucosaminyltransferase activity. There is experimental evidence that it is involved in the biological process</span>: protein amino acid glycosylation; wing disc development. 13 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: larval abdominal segment; anatomical structure; thoracic segment; adult segment; larval abdomen; larval thorax; organ system; adult mesothoracic segment; abdominal segment 4; abdominal segment 7; larval abdominal segment 5; antennal segment. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] The gene super sex combs is referred to in FlyBase by the symbol Dmel\sxc (CG10392, FBgn0261403). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:1194756..1216986. It has the cytological map location 41C1-41C2. There is experimental evidence that it has the molecular function</span>: acetylglucosaminyltransferase activity. There is experimental evidence that it is involved in the biological process</span>: protein amino acid glycosylation; wing disc development. 13 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: larval abdominal segment; anatomical structure; thoracic segment; adult segment; larval abdomen; larval thorax; organ system; adult mesothoracic segment; abdominal segment 4; abdominal segment 7; larval abdominal segment 5; antennal segment. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] The gene super sex combs is referred to in FlyBase by the symbol Dmel\sxc (CG10392, FBgn0261403). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:1194756..1216986. It has the cytological map location 41C1-41C2. There is experimental evidence that it has the molecular function</span>: acetylglucosaminyltransferase activity. There is experimental evidence that it is involved in the biological process</span>: protein amino acid glycosylation; wing disc development. 13 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: larval abdominal segment; anatomical structure; thoracic segment; adult segment; larval abdomen; larval thorax; organ system; adult mesothoracic segment; abdominal segment 4; abdominal segment 7; larval abdominal segment 5; antennal segment. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1059 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	wing disc development [IMP] protein amino acid glycosylation [IMP]
Molecular Function:	transferase activity, transferring glycosyl groups [NAS] acetylglucosaminyltransferase activity [IMP] binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHVEQTRINM QSQGQSHQLP SAAHILLDQN PNSTGSNLVV KQNDIQSLSS VGLLELAHRE  60
   61 YQAVDYESAE KHCMQLWRQD STNTGVLLLL SSIHFQCRRL DKSAQFSTLA IKQNPVLAEA 120
  121 YSNLGNVFKE RGQLQEALDN YRRAVRLKPD FIDGYINLAA ALVAARDMES AVQAYITALQ 180
  181 YNPDLYCVRS DLGNLLKALG RLEEAKACYL KAIETCPGFA VAWSNLGCVF NAQGEIWLAI 240
  241 HHFEKAVTLD PNFLDAYINL GNVLKEARIF DRAVAAYLRA LNLSPNNAVV HGNLACVYYE 300
  301 QGLIDLAIDT YRRAIELQPN FPDAYCNLAN ALKEKGQVKE AEDCYNTALR LCSNHADSLN 360
  361 NLANIKREQG YIEEATRLYL KALEVFPDFA AAHSNLASVL QQQGKLKEAL MHYKEAIRIQ 420
  421 PTFADAYSNM GNTLKELQDV SGALQCYTRA IQINPAFADA HSNLASIHKD SGNIPEAIQS 480
  481 YRTALKLKPD FPDAYCNLAH CLQIVCDWTD YDIRMKKLVS IVTEQLEKNR LPSVHPHHSM 540
  541 LYPLTHDCRK AIAARHANLC LEKVHVLHKK PYNFLKKLPT KGRLRIGYLS SDFGNHPTSH 600
  601 LMQSVPGLHD RSKVEIFCYA LSPDDGTTFR HKISRESENF VDLSQIPCNG KAADKIFNDG 660
  661 IHILVNMNGY TKGARNEIFA LRPAPIQVMW LGYPGTSGAS FMDYIITDSV TSPLELAYQY 720
  721 SEKLSYMPHT YFIGDHKQMF PHLKERIIVC DKQQSSVVDN VTVINATDLS PLVENTDVKE 780
  781 IKEVVNAQKP VEITHKVAEL PNTTQIVSMI ATGQVQTSLN GVVVQNGLAT TQTNNKAATG 840
  841 EEVPQNIVIT TRRQYMLPDD AVVYCNFNQL YKIDPQTLES WVEILKNVPK SVLWLLRFPA 900
  901 VGEQNIKKTV SDFGISPDRV IFSNVAAKEE HVRRGQLADI CLDTPLCNGH TTSMDVLWTG 960
  961 TPVVTLPGET LASRVAASQL ATLGCPELIA RTREEYQNIA IRLGTKKEYL KALRAKVWKA1020
 1021 RVESPLFDCS QYAKGLEKLF LRMWEKYENG ELPDHISAV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
binding	2.71974493738804	bayes_pls_golite062009
phosphoprotein phosphatase activity	2.48921024987872	bayes_pls_golite062009
phosphatase activity	2.4502869290841	bayes_pls_golite062009
phosphoric ester hydrolase activity	2.38923256228405	bayes_pls_golite062009
hydrolase activity	2.16486484513356	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	2.07186557005331	bayes_pls_golite062009
protein binding	1.6279032205159	bayes_pls_golite062009
protein serine/threonine phosphatase activity	0.949260584741775	bayes_pls_golite062009
transcription regulator activity	0.897652181945102	bayes_pls_golite062009
nucleic acid binding	0.89107071408431	bayes_pls_golite062009
acetylglucosaminyltransferase activity	0.78476205818302	bayes_pls_golite062009
signal sequence binding	0.71760275307167	bayes_pls_golite062009
DNA binding	0.69174990631975	bayes_pls_golite062009
transferase activity	0.127854220687373	bayes_pls_golite062009
transcription factor activity	0.0355464132591463	bayes_pls_golite062009

Term	Confidence	Notes
binding	2.64850159998065	bayes_pls_golite062009
phosphoprotein phosphatase activity	2.46843774028558	bayes_pls_golite062009
phosphatase activity	2.44706583719107	bayes_pls_golite062009
phosphoric ester hydrolase activity	2.38926130931194	bayes_pls_golite062009
hydrolase activity	2.18367327479473	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	2.08144339124986	bayes_pls_golite062009
protein binding	1.51322932625387	bayes_pls_golite062009
nucleic acid binding	0.911278924148848	bayes_pls_golite062009
transcription regulator activity	0.901700452557225	bayes_pls_golite062009
protein serine/threonine phosphatase activity	0.885740486338406	bayes_pls_golite062009
DNA binding	0.700415462149061	bayes_pls_golite062009
acetylglucosaminyltransferase activity	0.46284342518134	bayes_pls_golite062009
signal sequence binding	0.369400280321922	bayes_pls_golite062009
transferase activity	0.157308242400253	bayes_pls_golite062009
transcription factor activity	0.0427333667518928	bayes_pls_golite062009

No functions predicted.

Term	Confidence	Notes
phosphatase activity	3.16094149051954	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	3.13569872928774	bayes_pls_golite062009
transferase activity	3.03956822053273	bayes_pls_golite062009
phosphoric ester hydrolase activity	3.01850011456741	bayes_pls_golite062009
glycogen phosphorylase activity	3.01517792398516	bayes_pls_golite062009
mannosyltransferase activity	2.87904689842963	bayes_pls_golite062009
catalytic activity	2.42803950895063	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	2.3858480663855	bayes_pls_golite062009
phosphorylase activity	2.23274855299608	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.09333759861004	bayes_pls_golite062009
hydrolase activity	2.08253369482508	bayes_pls_golite062009
UDP-glycosyltransferase activity	1.65897712372683	bayes_pls_golite062009
binding	1.48043706849734	bayes_pls_golite062009
glucosyltransferase activity	1.31063355475817	bayes_pls_golite062009
acetylglucosaminyltransferase activity	1.23523057782505	bayes_pls_golite062009
UDP-glucosyltransferase activity	1.02641807500117	bayes_pls_golite062009
UDP-N-acetylglucosamine 2-epimerase activity	0.794706340814402	bayes_pls_golite062009
kinase activity	0.684809898353865	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.668043447312344	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.587634519373051	bayes_pls_golite062009
carbohydrate phosphatase activity	0.459821108931138	bayes_pls_golite062009
protein binding	0.205918655781648	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..352]	PSI-BLAST	80.522879	The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
2	View Details	[353..422]	FFAS03	4.6	Hop
3	View Details	[423..527]	PSI-BLAST	34.09691	Crystal structure of an 8 repeat consensus TPR superhelix (trigonal crystal form)
4	View Details	[528..1059]	FFAS03	2.67	Trehalose-6-phosphate from E. coli bound with UDP-2-fluoro glucose.

Protein Overview: sxc-PB, sxc-PC, ...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: