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View Structure Prediction Details

Protein: sxc-PB, sxc-PC, ...
Organism: Drosophila melanogaster
Length: 1059 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sxc-PB, sxc-PC, ....

Description E-value Query
Range
Subject
Range
gi|91079875 - gi|91079875|ref|XP_967579.1| PREDICTED: similar to CG10392-PB, isoform B [Tribolium castaneum]
923.0 [0..53] [1057..161]

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Predicted Domain #1
Region A:
Residues: [1-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHVEQTRINM QSQGQSHQLP SAAHILLDQN PNSTGSNLVV KQNDIQSLSS VGLLELAHRE  60
   61 YQAVDYESAE KHCMQLWRQD STNTGVLLLL SSIHFQCRRL DKSAQFSTLA IKQNPVLAEA 120
  121 YSNLGNVFKE RGQLQEALDN YRRAVRLKPD FIDGYINLAA ALVAARDMES AVQAYITALQ 180
  181 YNPDLYCVRS DLGNLLKALG RLEEAKACYL KAIETCPGFA VAWSNLGCVF NAQGEIWLAI 240
  241 HHFEKAVTLD PNFLDAYINL GNVLKEARIF DRAVAAYLRA LNLSPNNAVV HGNLACVYYE 300
  301 QGLIDLAIDT YRRAIELQPN FPDAYCNLAN ALKEKGQVKE AEDCYNTALR LC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.522879
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.71974493738804 bayes_pls_golite062009
phosphoprotein phosphatase activity 2.48921024987872 bayes_pls_golite062009
phosphatase activity 2.4502869290841 bayes_pls_golite062009
phosphoric ester hydrolase activity 2.38923256228405 bayes_pls_golite062009
hydrolase activity 2.16486484513356 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.07186557005331 bayes_pls_golite062009
protein binding 1.6279032205159 bayes_pls_golite062009
protein serine/threonine phosphatase activity 0.949260584741775 bayes_pls_golite062009
transcription regulator activity 0.897652181945102 bayes_pls_golite062009
nucleic acid binding 0.89107071408431 bayes_pls_golite062009
acetylglucosaminyltransferase activity 0.78476205818302 bayes_pls_golite062009
signal sequence binding 0.71760275307167 bayes_pls_golite062009
DNA binding 0.69174990631975 bayes_pls_golite062009
transferase activity 0.127854220687373 bayes_pls_golite062009
transcription factor activity 0.0355464132591463 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [353-422]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNHADSLNNL ANIKREQGYI EEATRLYLKA LEVFPDFAAA HSNLASVLQQ QGKLKEALMH  60
   61 YKEAIRIQPT 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.6
Match: 1elwA
Description: Hop
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.64850159998065 bayes_pls_golite062009
phosphoprotein phosphatase activity 2.46843774028558 bayes_pls_golite062009
phosphatase activity 2.44706583719107 bayes_pls_golite062009
phosphoric ester hydrolase activity 2.38926130931194 bayes_pls_golite062009
hydrolase activity 2.18367327479473 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.08144339124986 bayes_pls_golite062009
protein binding 1.51322932625387 bayes_pls_golite062009
nucleic acid binding 0.911278924148848 bayes_pls_golite062009
transcription regulator activity 0.901700452557225 bayes_pls_golite062009
protein serine/threonine phosphatase activity 0.885740486338406 bayes_pls_golite062009
DNA binding 0.700415462149061 bayes_pls_golite062009
acetylglucosaminyltransferase activity 0.46284342518134 bayes_pls_golite062009
signal sequence binding 0.369400280321922 bayes_pls_golite062009
transferase activity 0.157308242400253 bayes_pls_golite062009
transcription factor activity 0.0427333667518928 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [423-527]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FADAYSNMGN TLKELQDVSG ALQCYTRAIQ INPAFADAHS NLASIHKDSG NIPEAIQSYR  60
   61 TALKLKPDFP DAYCNLAHCL QIVCDWTDYD IRMKKLVSIV TEQLE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.09691
Match: 2fo7A
Description: Crystal structure of an 8 repeat consensus TPR superhelix (trigonal crystal form)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [528-1059]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNRLPSVHPH HSMLYPLTHD CRKAIAARHA NLCLEKVHVL HKKPYNFLKK LPTKGRLRIG  60
   61 YLSSDFGNHP TSHLMQSVPG LHDRSKVEIF CYALSPDDGT TFRHKISRES ENFVDLSQIP 120
  121 CNGKAADKIF NDGIHILVNM NGYTKGARNE IFALRPAPIQ VMWLGYPGTS GASFMDYIIT 180
  181 DSVTSPLELA YQYSEKLSYM PHTYFIGDHK QMFPHLKERI IVCDKQQSSV VDNVTVINAT 240
  241 DLSPLVENTD VKEIKEVVNA QKPVEITHKV AELPNTTQIV SMIATGQVQT SLNGVVVQNG 300
  301 LATTQTNNKA ATGEEVPQNI VITTRRQYML PDDAVVYCNF NQLYKIDPQT LESWVEILKN 360
  361 VPKSVLWLLR FPAVGEQNIK KTVSDFGISP DRVIFSNVAA KEEHVRRGQL ADICLDTPLC 420
  421 NGHTTSMDVL WTGTPVVTLP GETLASRVAA SQLATLGCPE LIARTREEYQ NIAIRLGTKK 480
  481 EYLKALRAKV WKARVESPLF DCSQYAKGLE KLFLRMWEKY ENGELPDHIS AV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.67
Match: 1uqtA
Description: Trehalose-6-phosphate from E. coli bound with UDP-2-fluoro glucose.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphatase activity 3.16094149051954 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 3.13569872928774 bayes_pls_golite062009
transferase activity 3.03956822053273 bayes_pls_golite062009
phosphoric ester hydrolase activity 3.01850011456741 bayes_pls_golite062009
glycogen phosphorylase activity 3.01517792398516 bayes_pls_golite062009
mannosyltransferase activity 2.87904689842963 bayes_pls_golite062009
catalytic activity 2.42803950895063 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.3858480663855 bayes_pls_golite062009
phosphorylase activity 2.23274855299608 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 2.09333759861004 bayes_pls_golite062009
hydrolase activity 2.08253369482508 bayes_pls_golite062009
UDP-glycosyltransferase activity 1.65897712372683 bayes_pls_golite062009
binding 1.48043706849734 bayes_pls_golite062009
glucosyltransferase activity 1.31063355475817 bayes_pls_golite062009
acetylglucosaminyltransferase activity 1.23523057782505 bayes_pls_golite062009
UDP-glucosyltransferase activity 1.02641807500117 bayes_pls_golite062009
UDP-N-acetylglucosamine 2-epimerase activity 0.794706340814402 bayes_pls_golite062009
kinase activity 0.684809898353865 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.668043447312344 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.587634519373051 bayes_pls_golite062009
carbohydrate phosphatase activity 0.459821108931138 bayes_pls_golite062009
protein binding 0.205918655781648 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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