Protein Overview: tsh-PA

General Information:
Name(s) found:	tsh-PA / FBpp0085261 [FlyBase]
Description(s) found: Found 20 descriptions. SHOW ALL	The gene teashirt is referred to in FlyBase by the symbol Dmel\tsh (CG1374, FBgn0003866). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:21828595..21837013. It has the cytological map location 40A5. There is experimental evidence that it has the molecular function</span>: transcription repressor activity. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: anatomical structure development; organ development; segment specification; embryonic pattern specification; regionalization; trunk segmentation; organ morphogenesis; system development; regulation of metabolic process; regulation of biological process. 52 alleles are reported. The phenotypes of these alleles are annotated with 55 unique terms, many of which group under: adult segment; organ system; peripheral nervous system; adult mesothoracic segment; cuticle; cell cycle; embryonic segment; nervous system; embryonic head; larval thorax. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	954 amino acids
Gene Ontology:
Cellular Component:	nucleus [NAS] intracellular [IEA]
Biological Process:	specification of segmental identity, head [IMP] imaginal disc-derived leg morphogenesis [TAS] negative regulation of salivary gland boundary specification [TAS] specification of segmental identity, thorax [IMP][NAS] specification of segmental identity, abdomen [NAS] wing disc proximal/distal pattern formation [IMP] head involution [IMP] imaginal disc-derived wing morphogenesis [IMP] specification of segmental identity, trunk [IMP] salivary gland development [NAS] compound eye development [IMP] regulation of transcription from RNA polymerase II promoter [IMP][NAS] leg disc proximal/distal pattern formation [IMP] negative regulation of transcription from RNA polymerase II promoter [IMP][NAS] epidermis morphogenesis [IMP]
Molecular Function:	zinc ion binding [IEA] specific RNA polymerase II transcription factor activity [NAS] transcription repressor activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLHEALMLEI YRQALNAGAL PTARPRSTES ANSSERCPSH DSNSSEHGGG AGSGGVGHRL  60
   61 DAAALSTGVM PGEGPTTLHS SFPAVPQSLP SQPPSMEAYL HMVAAAAQQY GFPLAAAAAA 120
  121 GAGPRLPLPL ANEAAAPFKL PPQASPTASS NNSEALDFRT NLYGRAESAE PPASEGEEEE 180
  181 FDDGANNPLD LSVGTRKRGH ESEPQLGHIQ VKKMFKSDSP PANSVASPSA SQLLPGVNPY 240
  241 LAAVAAANIF RAGQFPDWNS KNDLVVDPLE KMSDIVKGGA SGMGTKEKMH SSKATTPQAA 300
  301 SQPPKSPVQP TPNQNSESGG GSGGGAAGSG AVTKARHNIW QSHWQNKGVA SSVFRCVWCK 360
  361 QSFPTLEALT THMKDSKHCG VNVPPFGNLP SNNPQPQHHH PTPPPPPQNH NLRKHSSGSA 420
  421 SNHSPSANVK NAFQYRGDPP TPLPRKLVRG QNVWLGKGVE QAMQILKCMR CGESFRSLGE 480
  481 MTKHMQETQH YTNILSQEQS ISIKSGNANA NSDAKESHNS LSSEESRTLS AVLTCKVCDK 540
  541 AFNSLGDLSN HMAKNNHYAE PLLQSAGARK RPAPKKREKS LPVRKLLEMK GGSGTTQEDH 600
  601 SNEKTSVQGK PGLGPGGGDK NDAALFAERM RQYITGVKAP EEIAKVAAAQ LLAKNKSPEL 660
  661 VEQKNGGSAK AAGASSVLSA IEQMFTTSFD TPPRHASLPA SSPSNSSTKN TSPVASSILK 720
  721 RLGIDETVDY NKPLIDTNDP YYQHYRYTSS ERSGSECSAE ARPRLDAPTP EKQQQGGGHD 780
  781 EESSKPAIKQ EREAESKPVK MEIKSEFVDE PNEAEETSKM EAAVVNGSAT NNNNNIVERS 840
  841 SPKTPSSAAS PQTRLLPPRS PAESQRSVTP KSPASSHKSY DGSSEGTKKF PSDSLNALSS 900
  901 MFDSLGSSGA GANSRAKLAA AAAAGGSESP ENLTAGGNSL AALRQFCVKK EKTA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.91

Protein Overview: tsh-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: