Protein Overview: l(2)37Cb-PA

General Information:
Name(s) found:	l(2)37Cb-PA / FBpp0080706 [FlyBase]
Description(s) found: Found 21 descriptions. SHOW ALL	The gene lethal (2) 37Cb is referred to in FlyBase by the symbol Dmel\l(2)37Cb (CG10689, FBgn0086444). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:19123998..19126973. It has the cytological map location 37C5. Based on sequence similarity, it is predicted to have molecular function</span>: ATP-dependent RNA helicase activity; RNA helicase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: nuclear mRNA splicing, via spliceosome. 39 alleles are reported. The phenotype of these alleles is annotated with: adult thorax. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	894 amino acids
Gene Ontology:
Cellular Component:	catalytic step 2 spliceosome [IDA] precatalytic spliceosome [IDA] spliceosomal complex [ISS]
Biological Process:	nuclear mRNA splicing, via spliceosome [IC][ISS]
Molecular Function:	nucleic acid binding [IEA] ATP binding [IEA] RNA helicase activity [ISS] ATP-dependent RNA helicase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGKNRKRTA SSSSSGEEPD SEEESRLKDL QERDEFASRL KKRDDDRTRN VVDSTGGRRA  60
   61 IEEATKRLKL EHEDRDKIVP HLRLQSRRQY LEKRKDDKVA ELEADILDDE YLFDESVLTK 120
  121 REKEEREYKK QLLNIAKEHE KARELERIQR YNMPQDLKKG ERSEYVEVDE FEKQPNSEQK 180
  181 KWEAEQLASA RFHFGAKDAK AEEEYELLLD DQIDFIQALT LDGSREKSSS RQPELTEKER 240
  241 KRLTLDETRR SLPVYPFKED LIAAVKEHQV LIIEGETGSG KTTQVPQYLV EAGFTKDKKM 300
  301 IGCTQPRRVA AMSVAARVAE EMGVKLGNEV GYSIRFEDCT SDRTILKYMT DGTLHREFLS 360
  361 EPDLASYSVM IIDEAHERTL HTDILFGLVK DIARFRPELK LLISSATLDA EKFSAFFDDA 420
  421 PIFRIPGRRY PVDIFYTKAP EADYIDACCV SVLQIHATQP LGDILVFLTG QDEIETCQEV 480
  481 LHDRVKRLGS KIRELIVIPV YANLPSDMQA KIFEPTPPNA RKVILATNIA ETSLTIDNII 540
  541 YVIDPGFAKQ NNFNSRTGME SLMVVPISKA SANQRAGRAG RTAPGKCFRL YTAWAYKHEL 600
  601 EDNTVPEIQR INLGNAVLML KALGINDLIH FDFLDPPPHE TLVLALEQLY ALGALNHHGE 660
  661 LTKLGRRMAE FPVDPMMGKM LLASEKYKCS EEMVTIAAML SVNSAIFYRP KDKIIHADTA 720
  721 RKNFNHMHGD HLSLLQVYNQ WAETDYSTQW CYENFIQYRS MKRARDVREQ LVGLMQRVEI 780
  781 DMVSCLPETV NVRKAATAGY FYHVARLSKG GHYKTIKHNQ TVMIHPNSSL FEELPRWVLY 840
  841 HELVFTSKEY MRQVIEIESK WLLEVAPHYY KAKELEDSTN KKMPKVAGRA EMAQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: l(2)37Cb-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: