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Protein Overview: Porin2-PA, FBpp0...

General Information:
Name(s) found: FBpp0304344 [FlyBase]
Porin2-PA / FBpp0079773 [FlyBase]
Description(s) found:
Found 30 descriptions.
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  • type=protein; loc=2L:complement(10845888..10846218,10846282..10846506,10846573..10846898); ID=FBpp0304344; name=Porin2-PB; parent=FBgn0069354,FBtr0332030; dbxref=FlyBase:FBpp0304344,FlyBase_Annotation_IDs:CG17137-PB,REFSEQ:NP_001260364,GB_protein:AGB92899; MD5=54e6c152b38df27468d51cf21440039b; length=293; release=r5.56; species=Dmel; [FlyBase]
  • The gene Porin2 is referred to in FlyBase by the symbol Dmel\Porin2 (CG17137, FBgn0069354). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:10845783..10847044. It has the cytological map location 32B1. There is experimental evidence that it has the molecular function</span>: voltage-gated anion channel activity; porin activity; cation channel activity. There is experimental evidence that it is involved in the biological process</span>: ion transport. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 293 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDA][ISS]
    mitochondrial outer membrane [ISS]
    Biological Process: ion transport [IDA]
    transmembrane transport [IEA]
    mitochondrial transport [ISS]
    anion transport [IEA]
    Molecular Function: voltage-gated anion channel activity [IDA][ISS]
    porin activity [IDA]
    cation channel activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAKTPTYPD LGKLARDLFK RGYHPGIWQI DCKTLTNSGI EFFTTGFASQ DNSKVTGSLQ  60
   61 SKYKIEDQGL TLTERWNTEN WLFGEIMHRD KLAQGLMLAV EAKFQPGSNE ADGKFKMGYA 120
  121 QDNFNFLADI GLNSEPILNC SLVVGHKEFL GGVGTEFDVG NTELKGWKVA LGWTNETATL 180
  181 HGELKNGDTW LASLFYKASE KIDAGIEVTK GAGGGEAAEG EQQGGDVVVN LGMIYHLEED 240
  241 ALVRAKVNNL VELGLGYEQK LRDGITASIS AVLDCNNFKD GNHRFGVGIA LQC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..293] FFAS03 0.958 No description for 2ge4A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • channel activity
    		•  4.42063230929782 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  4.42063230929782 bayes_pls_golite062009
  • wide pore channel activity
    		•  3.23380189399278 bayes_pls_golite062009
  • porin activity
    		•  3.07546403538822 bayes_pls_golite062009
  • transporter activity
    		•  2.79333283601576 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.67610270255307 bayes_pls_golite062009
  • signal transducer activity
    		•  2.40233759168714 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.40233759168714 bayes_pls_golite062009
  • receptor activity
    		•  2.38771290025999 bayes_pls_golite062009
  • binding
    		•  1.39766737580326 bayes_pls_golite062009
  • protein binding
    		•  0.709353859897791 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle