Protein Overview: FBpp0308609, numb-PA

General Information:
Name(s) found:	FBpp0308609 [FlyBase] numb-PA / FBpp0079420 [FlyBase]
Description(s) found: Found 29 descriptions. SHOW ALL	type=protein; loc=2L:join(9460288..9460368,9460505..9460753,9460938..9462278); ID=FBpp0308609; name=numb-PD; parent=FBgn0002973,FBtr0339526; dbxref=FlyBase:FBpp0308609,FlyBase_Annotation_IDs:CG3779-PD,REFSEQ:NP_001260291,GB_protein:AGB92826; MD5=1cf77b1732033db240bd1a079e163e93; length=556; release=r5.56; species=Dmel; [FlyBase] The gene numb is referred to in FlyBase by the symbol Dmel\numb (CG3779, FBgn0002973). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:9437513..9463293. It has the cytological map location 30B3-30B5. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: protein localization; muscle cell fate specification; glial cell migration; neuroblast proliferation; asymmetric neuroblast division; regulation of neurogenesis; sensory organ precursor cell division; pericardial cell differentiation. 79 alleles are reported. The phenotypes of these alleles are annotated with 206 unique terms, many of which group under: hypodermal muscle of larval abdomen; organ system; adult abdominal myoblast; peripheral nervous system; larval abdominal segment 5; abdominal oblique muscle; embryonic neuron; embryonic nervous system; nervous system; abdominal transverse muscle. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	556 amino acids
Gene Ontology:
Cellular Component:	nucleus [NAS] basal part of cell [NAS][TAS] cytoplasm [TAS] cell cortex [IDA] basal cortex [NAS]
Biological Process:	regulation of Notch signaling pathway [TAS] protein localization [IMP] neuroblast fate determination [NAS][TAS] peripheral nervous system development [TAS] asymmetric cell division [NAS][TAS] muscle cell fate specification [IMP] negative regulation of Notch signaling pathway [TAS] pericardial cell differentiation [IMP] rhythmic behavior [TAS] glial cell migration [IMP] heart development [TAS] ventral cord development [NAS] neuroblast proliferation [IMP] Notch signaling pathway [TAS] central nervous system development [TAS] sensory organ precursor cell division [IMP] sensory organ precursor cell fate determination [NAS][TAS] cell fate commitment [TAS] asymmetric neuroblast division [IMP][TAS] cell fate determination [NAS] regulation of neurogenesis [IMP]
Molecular Function:	nucleic acid binding [NAS] protein binding [IPI] Notch binding [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNSSSHTHE PLERGFTRGK FGDVKNGKSA SFRFSKKSPK KMDRLRRSFR DSFRRRKDRV  60
   61 PESSKPHQWQ ADEEAVRSAT CSFSVKYLGC VEVFESRGMQ VCEEALKVLR QSRRRPVRGL 120
  121 LHVSGDGLRV VDDETKGLIV DQTIEKVSFC APDRNHERGF SYICRDGTTR RWMCHGFLAC 180
  181 KDSGERLSHA VGCAFAVCLE RKQRRDKECG VTMTFDTKNS TFTRTGSFRQ QTLTERLAMA 240
  241 TVGTNERSVD GPGSAMPGPP AATVKPFNPF AIERPHATPN MLERQSSFRL STIGSQSPFK 300
  301 RQMSLRINDL PSNADRQRAF LTAAAGNPMQ TPLRSVSPIA EVSPAKSAGA DPLSAAAVAA 360
  361 DSVSQLCQEL SQGLSLLTQT DALLAAGEDL NFNNNRSINQ NIIAAEKQVQ HVHSYAPPTA 420
  421 QVTPRVASTT PTYQTLHSQS PSRSEQSIET STELPNAEQW LGHVVRSTSP AAPKRPTYLA 480
  481 NVGRAQTLAS GTGAAVGGGG PDDPFDAEWV ANVAAAKQLS PDLPIPSTAR SPLARHSTNP 540
  541 FISPPKAPAQ SFQVQL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: FBpp0308609, numb-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: