Protein Overview: Pvr-PA

General Information:
Name(s) found:	Pvr-PA / FBpp0079244 [FlyBase]
Description(s) found: Found 20 descriptions. SHOW ALL	The gene PDGF- and VEGF-receptor related is referred to in FlyBase by the symbol Dmel\Pvr (CG8222, FBgn0032006). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:8220980..8239875. It has the cytological map location 28F4-28F5. There is experimental evidence that it has the molecular function</span>: transmembrane receptor protein tyrosine kinase activity; protein binding. There is experimental evidence for 13 unique biological process</span> terms, many of which group under: anatomical structure development; organ development; regulation of developmental process; actin filament-based process; organelle organization; cellular component movement; response to DNA damage stimulus; immune response; cell projection organization; gland morphogenesis; reproductive process in a multicellular organism; cell cycle. 61 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system; hemocyte; embryonic/larval hemocoel; embryonic nervous system; nervous system; female germline cyst; adult segment; adult mesothoracic segment; thoracic segment; embryonic glial cell; Kc167 cell-line; dorsal thoracic disc; multi-cell-component structure; peripheral nervous system. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1509 amino acids
Gene Ontology:
Cellular Component:	plasma membrane [IDA][ISS][NAS]
Biological Process:	hemocyte migration [IMP][TAS] regulation of cell shape [IMP] hemocyte proliferation [TAS] hemopoiesis [IEP] cell projection assembly [IMP] regulation of hemocyte differentiation [IMP] hemocyte differentiation [NAS] actin filament organization [IMP] border follicle cell migration [IGI][IMP][TAS] protein amino acid phosphorylation [IEA][NAS] response to DNA damage stimulus [IMP] salivary gland morphogenesis [IMP] ventral cord development [IMP] mitotic spindle elongation [IMP] vascular endothelial growth factor receptor signaling pathway [ISS] antimicrobial humoral response [IMP] actin cytoskeleton organization [IMP]
Molecular Function:	ATP binding [IEA] protein tyrosine kinase activity [NAS] protein binding [IPI] transmembrane receptor protein tyrosine kinase activity [IPI][ISS] vascular endothelial growth factor receptor activity [ISS][NAS] platelet-derived growth factor receptor activity [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMLPRLILL PLLLILRISW SDAVPLQQFS PDPDDSIENC GGENGAPLMT PCKSAIILDA  60
   61 QTSTTLKCED DEPMSWWTSQ SQYVHVKSFD NTEDPARPFG TSLHLIEVTA DYVAAYYCVK 120
  121 TSKFSQIAKE EQSDEAMIEL VNQGYASSIY VYVNDPDTKL VDSHNVVTAR QYTDVVIPCK 180
  181 PAMPDTEVLL ETSNGESTWK ISSKGQIQGN PKFFDSVRYH PRWGFTFRVI DCVSGYLYCK 240
  241 TLDYELIIDV TYPEKDGKPL PKPVIRSSVE HHVFTDTNFT LDCEQSAYVE SVYGMEWFTP 300
  301 SRDENRIFAS QSRTDPKTRN STHQTGRSTL TVLNAQPSDT GLYKCVTTDN SNQNVQRATY 360
  361 RIKVLKQNES YLNVGEPSGH YNVQEYANRT IQMTANFEGF PTPSFSWFKP DGTEVRQSEN 420
  421 NFKILSTELS TMLQVLNAQL QDSGTYVLRG SNSFGVVQRE YNVSVMDAPA LKMSDAYVQV 480
  481 GSVARLECTV RSYPPAIVTF FFRPCSLEPQ WPTCSVLNQN FSLPSEQEKY QFQTRPRPGK 540
  541 LSVERIYEVS FLPTEPGILT CIAQNIIDGK ERRTLTKAHV LLGNISENMT IYGFDKDHKI 600
  601 AKEDNVNFTC EALAYHFDGN LKWFINGEDL KESDSVHIET SHTKYSYKST VHITTISDRD 660
  661 RGTYECRAYH NDKDAVYSSR EIDLYVHDPS APQWTNGGQE GHSKIKRKLS QTLELECAST 720
  721 AVPVAIVRWF KDDKEVTESK LRHIIEKESK LLITHLYPGD EGVYKCVVEN RLDRIERSFT 780
  781 VVISDLPGIS MAWVWFGVIL FLILIGLCVF LAVRYQKEHK RHLALKAAGL ANFEEGAVGH 840
  841 INPDLTLDEQ AELLPYNREF EFPRENLKLG KQLGAGAFGV VLKGEAKGIR REEPTTTVAV 900
  901 KMVKATADNE VVRALVSELK IMVHLGQHLN VVNLLGAVTK NIAKRELMVI VEYCRFGNIQ 960
  961 NFLLRNRKCF INQINPDTDH IDPSIMTQRM SDNYELHRDT NGGGLKYANV GFPIHSYINE1020
 1021 PHNNNTQPPT HRRNSDNDPR SGTRAGRTGS GTATYSYDRQ MDTCATVMTT VPEDDQIMSN1080
 1081 NSVQPAWRSN YKTDSTEAMT VTTVDLISWA FQVARGMDYL SSKKVLHGDL AARNILLCED1140
 1141 NVVKICDFGL ARSMYRGDNY KKSENGKLPI KWLALESLSD HVFSTYSDVW SYGIVLWEMF1200
 1201 SLAKVPYPGI DPNQELFNKL NDGYRMEKPK FANQELYEIM LECWRKNPES RPLFAELEKR1260
 1261 FANMLGEDVA SHYLDLNNPY MQSNIEYMKK QSTDYLALMG SPDELAPAAP RYVNGHIVPD1320
 1321 IRIEELPDDY MEMSRDSDPD ACTAIFSPTR LEGESSDFPD FSSETTFNFP GARQSPTLSN1380
 1381 NLNSGSSKPL RKKNGMPTVD VADQAPEEIP MLHRSSTGSD GSPEQGRRFN QALKQQYVTP1440
 1441 TPSPRHHVET KLNGEPSENY VNMKPPRKNI PGKTTTGGGG AAAGASTEAF SNPSYQPLST1500
 1501 VNEKEQRRY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: Pvr-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: