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Protein Overview: FBpp0303793, snR...

General Information:
Name(s) found: FBpp0303793 [FlyBase]
snRNP70K-PA / FBpp0078983 [FlyBase]
Description(s) found:
Found 33 descriptions.
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  • type=protein; loc=2L:complement(6970116..6971462); ID=FBpp0303793; name=snRNP-U1-70K-PC; parent=FBgn0016978,FBtr0331375; dbxref=FlyBase:FBpp0303793,FlyBase_Annotation_IDs:CG8749-PC,REFSEQ:NP_001260173,GB_protein:AGB92709; MD5=34fea8422797af8da3ba4d8e80f9a551; length=448; release=r5.56; species=Dmel; [FlyBase]
  • The gene small nuclear ribonucleoprotein 70K is referred to in FlyBase by the symbol Dmel\snRNP70K (CG8749, FBgn0016978). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:6969825..6971736. It has the cytological map location 27C7-27D1. There is experimental evidence that it has the molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: negative regulation of nuclear mRNA splicing, via spliceosome; mitotic spindle organization; regulation of alternative nuclear mRNA splicing, via spliceosome. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 448 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IC]
    catalytic step 2 spliceosome [IDA]
    precatalytic spliceosome [IDA]
    U11 snRNP [ISS]
    small nuclear ribonucleoprotein complex [ISS]
    U1 snRNP [ISS]
    Biological Process: regulation of alternative nuclear mRNA splicing, via spliceosome [IMP]
    negative regulation of nuclear mRNA splicing, via spliceosome [IPI]
    mitotic spindle organization [IMP]
    nuclear mRNA splicing, via spliceosome [IC][ISS][NAS]
    Molecular Function: nucleotide binding [IEA]
    U1 snRNA binding [NAS]
    mRNA binding [IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQYLPPNLL ALFAAREPIP FMPPVDKLPH EKKSRGYLGV AKFMADFEDP KDTPLPKTVE  60
   61 TRQERLERRR REKAEQVAYK LEREIALWDP TEIKNATEDP FRTLFIARIN YDTSESKLRR 120
  121 EFEFYGPIKK IVLIHDQESG KPKGYAFIEY EHERDMHAAY KHADGKKIDS KRVLVDVERA 180
  181 RTVKGWLPRR LGGGLGGTRR GGNDVNIKHS GREDNERERE RYRLERERED REGPGRGGGS 240
  241 NGLDARPGRG FGAERRRSRS RERRDRERDR GRGAVASNGR SRSRSRERRK RRAGSRERYD 300
  301 EFDRRDRRDR ERERDRDRER EKKKKRSKSR ERESSRERRE RKRERRDRER GTGSGGDVKE 360
  361 RKPDFRDMDV IKIKEEPVDD GYPTFDYQNA TIKREIDDED EEKYRPPPAH HNMFSVPPPP 420
  421 ILGRGNASTN PNPDNGQQSS GDPSWWRQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle