Protein Overview: Spn27A-PA, FBpp0...

General Information:
Name(s) found:	FBpp0305543 [FlyBase] Spn27A-PA / FBpp0078950 [FlyBase]
Description(s) found: Found 30 descriptions. SHOW ALL	type=protein; loc=2L:complement(6671832..6673175); ID=FBpp0305543; name=Spn27A-PB; parent=FBgn0028990,FBtr0333351; dbxref=REFSEQ:NP_001260143,GB_protein:AGB92679,FlyBase:FBpp0305543,FlyBase_Annotation_IDs:CG11331-PB; MD5=ae5832cb83e450ed023d153de405327e; length=447; release=r5.56; species=Dmel; [FlyBase] The gene Serpin-27A is referred to in FlyBase by the symbol Dmel\Spn27A (CG11331, FBgn0028990). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:6671778..6673344. It has the cytological map location 26F6. There is experimental evidence that it has the molecular function</span>: enzyme inhibitor activity; serine-type endopeptidase inhibitor activity. There is experimental evidence that it is involved in the biological process</span>: defense response to fungus; defense response to insect; negative regulation of proteolysis; Toll signaling pathway; negative regulation of melanization defense response; response to wounding; dorsal/ventral axis specification; melanotic encapsulation of foreign target. 15 alleles are reported. The phenotypes of these alleles are annotated with: embryonic epidermis; wing; embryonic dorsal epidermis. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	447 amino acids
Gene Ontology:
Cellular Component:	extracellular region [IDA]
Biological Process:	defense response to insect [IMP] melanotic encapsulation of foreign target [IMP] Toll signaling pathway [IDA] response to wounding [IMP] negative regulation of melanization defense response [IMP][TAS] negative regulation of proteolysis [IDA] dorsal/ventral axis specification [IMP] defense response to fungus [IMP] melanization defense response [TAS]
Molecular Function:	serine-type endopeptidase inhibitor activity [IDA][ISS][NAS] enzyme inhibitor activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKMGGNLAV MLLSLFLSAL ATGNGNSIPT TTTPQGVFET RTDKLPGGAA SVPSGAGIYD  60
   61 DIDTFVPFRS DSHDPFSWHL LKTVLQNETA DKNVIISPFS VKLVLALLAE AAGAGTQTQV 120
  121 ELANTQTDIR SQNNVREFYR KTLNSFKKEN QLHETLSVRT KLFTDSFIET QQKFTATLKH 180
  181 FYDSEVEALD FTNPEAAADA INAWAANITQ GRLQQLVAPD NVRSSVMLLT NLIYFNGLWR 240
  241 RQFATTFQGS FFRSKDDQSR AEFMEQTDYF YYTTSEKLKA QILRLPYKGK NSLFVLLPYA 300
  301 LNGIHDLVKN LENDELKSAQ WAMEEVKVKV TLPKFHFDYQ QNLKETLRSL GVREIFEDSA 360
  361 SLPGLTRGAD VAGKVKVSNI LQKAGINVNE KGTEAYAATV VEIENKFGGS TAIEEFNVNR 420
  421 PFVFFIEEES TGNILFAGKV HSPTTQN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: Spn27A-PA, FBpp0...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: