Protein Overview: FBpp0302039, mid-PA

General Information:
Name(s) found:	FBpp0302039 [FlyBase] mid-PA / FBpp0078726 [FlyBase]
Description(s) found: Found 27 descriptions. SHOW ALL	type=protein; loc=2L:join(5461918..5462104,5463819..5464269,5465220..5465505,5465894..5466712); ID=FBpp0302039; name=mid-PB; parent=FBgn0261963,FBtr0310358; dbxref=FlyBase:FBpp0302039,FlyBase_Annotation_IDs:CG6634-PB,REFSEQ:NP_001260096,GB_protein:AGB92632; MD5=a7be8709c4eb9e5383dabd00b169c92a; length=580; release=r5.56; species=Dmel; [FlyBase] The gene midline is referred to in FlyBase by the symbol Dmel\mid (CG6634, FBgn0005511). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:5461641..5467609. It has the cytological map location 25E2. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: central nervous system development; cardioblast cell fate commitment; neuroblast fate specification; regulation of cardioblast differentiation; heart development; axon guidance; negative regulation of gene expression; embryonic heart tube development; segment polarity determination; neuroblast development. 14 alleles are reported. The phenotypes of these alleles are annotated with 19 unique terms, many of which group under: organ system; embryonic nervous system; primordium; cuticle; embryonic/larval dorsal vessel; anatomical structure; organ system subdivision; ventral nerve cord primordium; embryonic neuron; nervous system. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	580 amino acids
Gene Ontology:
Cellular Component:	nucleus [ISS]
Biological Process:	regulation of cell fate specification [IGI] leg disc pattern formation [IGI] segment polarity determination [IMP] regulation of transcription, DNA-dependent [IEA] axon guidance [IMP] cardioblast cell fate commitment [IMP] embryonic heart tube development [IMP] regulation of transcription [IEA][ISS] heart development [IMP] negative regulation of gene expression [IGI][IMP] central nervous system development [IGI][IMP] regulation of cardioblast differentiation [IMP] neuroblast development [IMP] neuroblast fate specification [IMP]
Molecular Function:	transcription factor activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVGSHPYLC NGVPAAPAAP NASGQTTTTA SKSAAGSATD FSIAAIMARE DASSRESSIR  60
   61 SASPISVEDE VDVDVVDCSD AEEPPTKARR LNHHQHHQHH QHHHNNNNNN NNNNVAHKSR 120
  121 NSGGAVAQTA SAESQLNTSS TSSQGRCSTP PQSPGTEDSE ERLTPEPVQK APKIVGSCNC 180
  181 DDLKPVQCHL ETKELWDRFH DLGTEMIITK TGRRMFPTVR VSFSGPLRQI QPADRYAVLM 240
  241 DIIPMDSKRY RYAYHRSAWL VAGKADPAPP ARLYAHPDSP FSCEALRKQV ISFEKVKLTN 300
  301 NEMDKNGQIV LNSMHRYQPR IHLVRLSHGQ SIPSNPKELQ DLDHKTYVFP ETVFTAVTAY 360
  361 QNQLITKLKI DSNPFAKGFR DSSRLTDFDR DPMEALLLEQ QLRSPLRLFP DPLMQQFAAQ 420
  421 GDPSSMALFE KARQHLQMFG GNSPYAQLMM PQMYQAAAAA AGPPPPPPGL GAFHMFQQQW 480
  481 PQLTAGFLAS ANQQAAAAQA AAQAQAQAQA AAAAMAANRT PPPPPTASTP SSTSSGSPSP 540
  541 DMRPRQYQRF SPYQLPGGQG PPSSAAGSPP AVNASRSPAH

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.72

Protein Overview: FBpp0302039, mid-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: