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Protein Overview: GFRP_RAT

General Information:
Name(s) found: GFRP_RAT [Swiss-Prot]
Description(s) found:
Found 77 descriptions.
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  • GTP cyclohydrolase 1 feedback regulatory protein OS=Rattus norvegicus GN=Gchfr PE=1 SV=3 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 84 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IEA]
    dendrite [UNKNOWN][IEA]
    nuclear membrane [UNKNOWN][IEA]
    soluble fraction [IDA]
    cytoplasm [UNKNOWN][IEA]
    melanosome [UNKNOWN][IEA]
    membrane [IEA]
    cytosol [IEA]
    protein complex [IDA]
    Biological Process: protein complex assembly [IDA]
    negative regulation of biosynthetic process [IEA]
    protein heterooligomerization [IDA]
    negative regulation of GTP cyclohydrolase I activity [IDA]
    regulation of nitric oxide biosynthetic process [NAS]
    Molecular Function: protein binding [UNKNOWN]
    enzyme inhibitor activity [IDA]
    amino acid binding [IDA]
    enzyme binding [IDA]
    GTP-dependent protein binding [IPI]
    GTP cyclohydrolase I binding [IDA][IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPYLLISTQI RMEVGPTMVG DEHSDPELMQ QLGASKRRVL GNNFYEYYVN DPPRIVLDKL  60
   61 ECRGFRVLSM TGVGQTLVWC LHKE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..84] PSI-BLAST 44.09691 GTP cyclohydrolase I feedback regulatory protein, GFRP


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle