Protein Overview: HTRA1_RAT

General Information:
Name(s) found:	HTRA1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|5815461\|gb\|AAD52683.1\|AF179370_1 insulin-like growth factor binding protein 5 protease [Rattus norvegicus] [NCBI NR] gi\|51859442\|gb\|AAH81767.1\| HtrA serine peptidase 1 [Rattus norvegicus] [NCBI NR] gi\|149067579\|gb\|EDM17131.1\| HtrA serine peptidase 1, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|13929012\|ref\|NP_113909.1\| HtrA serine peptidase 1 [Rattus norvegicus] [NCBI NR] Serine protease HTRA1 OS=Rattus norvegicus GN=Htra1 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):1-184059110 Insulin-like growth factor binding protein 5 protease [hmr_yeast5_DM3-1_pombe.fasta] protease, serine, 11; protease, serine, 11 (Igf binding); protease serine 11 (Igf binding) [HMR_022704-rand.fasta] protease, serine, 11; protease serine 11 (Igf binding); protease, serine, 11 (Igf binding) [071204_hmrz_cont.fasta] protease, serine, 11 [Rattus norvegicus]gi\|51859442\|gb\|AAH81767.1\| Protease, serine, 11 [Rattus norvegicus]gi\|5815461\|gb\|AAD52683.1\| insulin-like growth factor binding protein 5 protease [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Insulin-like growth factor binding protein 5 protease [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_031721) protease, serine, 11; protease, serine, 11 (Igf binding) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] HtrA serine peptidase 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] HtrA serine peptidase 1, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] insulin-like growth factor binding protein 5 protease [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 5 PROTEASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] protease, serine, 11 [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Htra1 HtrA serine peptidase 1, isoform CRA_a [rat-ipi-250309-contam.fasta] serine protease HTRA1 [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] HtrA serine peptidase 1 OS=Rattus norvegicus GN=Htra1 [011711_HMR.fasta] HtrA serine peptidase 1 OS=Rattus norvegicus GN=Htra1 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	480 amino acids
Gene Ontology:
Cellular Component:	extracellular region [IEA]
Biological Process:	negative regulation of BMP signaling pathway [UNKNOWN][IEA] regulation of cell growth [IEA] proteolysis [IEA] negative regulation of transforming growth factor beta receptor signaling pathway [UNKNOWN][IEA]
Molecular Function:	protein binding [UNKNOWN][IEA] catalytic activity [IEA] serine-type endopeptidase activity [IEA] peptidase activity [IEA] insulin-like growth factor binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQFLRTALLS LLLLLLAAPS LALPSGISRS APAATVCPEH CDPTRCAPPP TDCEGGRVRD  60
   61 ACGCCEVCGA LEGAVCGLQE GPCGEGLQCV VPFGVPASAT VRRRAQAGLC VCASSEPVCG 120
  121 SDAKTYTNLC QLRAASRRSE KLRQPPVIVL QRGACGQGQE DPNSLRHKYN FIADVVEKIA 180
  181 PAVVHIELYR KLPFSKREVP VASGSGFIVS EDGLIVTNAH VVTNKNRVKV ELKNGATYEA 240
  241 KIKDVDEKAD IALIKIDHQG KLPVLLLGRS SELRPGEFVV AIGSPFSLQN TVTTGIVSTT 300
  301 QRGGKELGLR NSDMDYIQTD AIINYGNSGG PLVNLDGEVI GINTLKVTAG ISFAIPSDKI 360
  361 KKFLTESHDR QAKGKTVTKK KYIGIRMMSL TSSKAKELKD RHRDFPDVIS GAYIIEVIPD 420
  421 TPAEAGGLKE NDVIISINGQ SVVTANDVSD VIKKENTLNM VVRRGNEDIV ITVVPEEIDP 480
  481

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: HTRA1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: