Protein Overview: DOPD_RAT

General Information:
Name(s) found:	DOPD_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|895882\|emb\|CAA85429.1\| D-dopachrome tautomerase [Rattus norvegicus] [NCBI NR] pir\|\|S68237 D-dopachrome tautomerase - rat [NCBI NR] gi\|149043739\|gb\|EDL97190.1\| D-dopachrome tautomerase, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|13162287\|ref\|NP_077045.1\| D-dopachrome tautomerase [Rattus norvegicus] [NCBI NR] gi\|1169390\|sp\|P80254.3\|DOPD_RAT RecName: Full=D-dopachrome decarboxylase; AltName: Full=D-dopachrome tautomerase [NCBI NR] D-dopachrome decarboxylase OS=Rattus norvegicus GN=Ddt PE=1 SV=3 [Swiss-Prot] Ensembl_locations(Chr-bp):20-13153153 D-dopachrome tautomerase [hmr_yeast5_DM3-1_pombe.fasta] D-dopachrome tautomerase; dopachrome isomerase [HMR_022704-rand.fasta] D-dopachrome tautomerase [Rattus norvegicus]gi\|895882\|emb\|CAA85429.1\| D-dopachrome tautomerase [Rattus norvegicus]gi\|1169390\|sp\|P80254\|DOPD_RAT D-dopachrome tautomerasegi\|2143698\|pir\|\|S68237 D-dopachrome tautomerase - rat [nrdb_11152004_Chlamydomonas] (NM_024131) D-dopachrome tautomerase [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] D-dopachrome decarboxylase (D-dopachrome tautomerase) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] D-dopachrome tautomerase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] D-dopachrome tautomerase, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 D-DOPACHROME TAUTOMERASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Ddt D-dopachrome decarboxylase [rat-ipi-250309-contam.fasta] D-dopachrome decarboxylase OS=Rattus norvegicus GN=Ddt [011711_HMR.fasta] Isoform of P80254, D-dopachrome decarboxylase OS=Rattus norvegicus GN=Ddt PE=1 SV=1 [RAT.fasta.20160308]
Organism:	Rattus norvegicus
Length:	118 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA]
Biological Process:	melanin biosynthetic process [IEA] inflammatory response [NAS]
Molecular Function:	protein binding [UNKNOWN] lyase activity [IEA] D-dopachrome decarboxylase activity [IEA] dopachrome isomerase activity [TAS]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MPFVELETNL PASRIPAGLE NRLCAATATI LDKPEDRVSV TIRPGMTLLM NKSTEPCAHL 60 61 LISSIGVVGT AEQNRSHSSS FFKFLTEELS LDQDRIIIRF FPLEPWQIGK KGTVMTFL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

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No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..118]	PSI-BLAST	36.69897	D-dopachrome tautomerase

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
phenylpyruvate tautomerase activity	3.84932786282501	bayes_pls_golite062009
cytokine activity	2.80410252537768	bayes_pls_golite062009
intramolecular oxidoreductase activity	2.17252244354636	bayes_pls_golite062009
binding	1.9717928129965	bayes_pls_golite062009
receptor binding	1.79096938850925	bayes_pls_golite062009
protein binding	1.70051621352839	bayes_pls_golite062009
catalytic activity	0.836951613125537	bayes_pls_golite062009
isomerase activity	0.804529932513639	bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing C=C bonds	0.452407074010503	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.93

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle