Protein Overview: IKKB_RAT

General Information:
Name(s) found:	IKKB_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6650707\|gb\|AAF21978.1\|AF115282_1 IKB kinase beta; IKK beta [Rattus norvegicus] [NCBI NR] gi\|16758078\|ref\|NP_445807.1\| inhibitor of kappaB kinase beta [Rattus norvegicus] [NCBI NR] gi\|14285495\|sp\|Q9QY78.1\|IKKB_RAT RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit beta; Short=I-kappa-B-kinase beta; Short=IkBKB; Short=IKK-beta; Short=IKK-B; AltName: Full=I-kappa-B kinase 2; Short=IKK2; AltName: Full=Nuclear factor NF-ka [NCBI NR] Inhibitor of nuclear factor kappa-B kinase subunit beta OS=Rattus norvegicus GN=Ikbkb PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):16-69784048 Inhibitor of nuclear factor kappa B kinase beta subunit [hmr_yeast5_DM3-1_pombe.fasta] inhibitor of kappa light polypeptide gene enhancer in B-cells, k [HMR_022704-rand.fasta] inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta [071204_hmrz_cont.fasta] inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta [Rattus norvegicus]gi\|14285495\|sp\|Q9QY78\|IKKB_RAT Inhibitor of nuclear factor kappa B kinase beta subunit (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) ( [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Inhibitor of nuclear factor kappa B kinase beta subunit [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_053355) inhibitor of kappa light polypeptide gene enhancer in B-cells, k [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] IKB kinase beta; IKK beta [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 INHIBITOR OF NUCLEAR FACTOR KAPPA B KINASE BETA SUBUNIT [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Inhibitor of nuclear factor kappa B kinase subunit beta (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) [nr-271106-contam.fasta] inhibitor of kappaB kinase beta [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Ikbkb Inhibitor of nuclear factor kappa-B kinase subunit beta [rat-ipi-250309-contam.fasta] Inhibitor of nuclear factor kappa-B kinase subunit beta OS=Rattus norvegicus GN=Ikbkb [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	757 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [UNKNOWN][IDA] IkappaB kinase complex [IPI] membrane [IEA] membrane raft [IEA] microsome [IDA] cytosol [UNKNOWN]
Biological Process:	skeletal muscle contraction [IEP] anti-apoptosis [UNKNOWN] I-kappaB phosphorylation [IDA][IMP] response to drug [IEP] regulation of I-kappaB kinase/NF-kappaB cascade [IMP] protein amino acid phosphorylation [IEA] response to toxin [IEP] positive regulation of NF-kappaB transcription factor activity [UNKNOWN][IMP] B cell homeostasis [UNKNOWN][IEA]
Molecular Function:	nucleotide binding [IEA] ATP binding [IDA][IEA] identical protein binding [UNKNOWN][IEA] protein binding [UNKNOWN][IDA][IPI] protein heterodimerization activity [IPI] IkappaB kinase activity [IEA] protein kinase activity [UNKNOWN][IDA][IMP] protein serine/threonine kinase activity [IEA] transferase activity [IEA] kinase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWSPSLPTQ TCGAWEMKER LGTGGFGNVI RWHNQVTGEQ IAIKQCRQEL SPKNRDRWCL  60
   61 EIQIMRRLNH PNVVAARDVP EGMQNLAPND LPLLAMEYCQ GGDLRRYLNQ FENCCGLREG 120
  121 AILTLLSDIA SALRYLHENR IIHRDLKPEN IVLQQGEKRL IHKIIDLGYA KELDQGSLCT 180
  181 SFVGTLQYLA PELLEQQKYT VTVDYWSFGT LAFECITGFR PFLPNWQPVQ WHSKVRQKSE 240
  241 VDIVVSEDLN GTVKFSSSSP FPNNLNSVLA ERLEKWLQLM LTWQPRQRGV DPQYGPNGCF 300
  301 RALDDILNLK LVHILNMVTG TIHTYPVMED ESLQSLKTRI REDTGILETD QELLQEAGLV 360
  361 LLPDKPATQC ISDSKTNEGL TLDMDLVFLF DNSKMSYETQ ITPRPQPESV SCVLQEPKRN 420
  421 LSFFQMRKVW GQVWHSIQTL KEDCNRLQQG QRAAMMNLLR NNSCLSKMKN AMASTAQQLK 480
  481 AKLDFFKTSI QIDLEKYREQ TEFGITSDKL LLAWREMEQA VEQCGRENDV KVLVERMMAL 540
  541 QTDIVDLQRS PMGRKQGGTL DDLEEQAREL YRRLREKPRD QRTEGDSQDM VRLLLQAIQS 600
  601 FEKKVRVIYS QLSKTVVCKQ KALELLPKVE EVVRLMNEDE KTVVRLQEKR QKELWNLLKI 660
  661 ACSKVRGPVS GSPDSMNVSR LSHPGHLMSQ PSSACDSLPD SDKKSEELVA EAHALCSRLE 720
  721 SALQDTVKQQ DRSFTTLDWS WLQMEDEERC GLEQACD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: IKKB_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: