Protein Overview: HXK4_RAT

General Information:
Name(s) found:	HXK4_RAT [Swiss-Prot]
Description(s) found: Found 13 descriptions. SHOW ALL	Glucokinase OS=Rattus norvegicus GN=Gck PE=1 SV=2 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	465 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] soluble fraction [UNKNOWN] cytoplasm [IDA][IMP] cell cortex [IDA] secretory granule [IDA] mitochondrion [UNKNOWN][IDA] cytosol [UNKNOWN][IDA] actin filament [IDA] nucleoplasm [UNKNOWN][IDA] cell cortex part [IDA]
Biological Process:	positive regulation of phosphorylation [IDA] glycolysis [IDA] regulation of potassium ion transport [UNKNOWN] fructose 2,6-bisphosphate metabolic process [IDA] negative regulation of gluconeogenesis [UNKNOWN][ISS] glucose metabolic process [UNKNOWN][IDA] carbohydrate phosphorylation [UNKNOWN][IDA] positive regulation of glycogen biosynthetic process [UNKNOWN][ISS] cellular response to glucose starvation [IMP] positive regulation of glycolysis [IDA] elevation of cytosolic calcium ion concentration [IDA] carbohydrate metabolic process [IEA] regulation of insulin secretion [UNKNOWN] glycogen biosynthetic process [IDA] response to glucose stimulus [IEP] glucose 6-phosphate metabolic process [IDA] cellular glucose homeostasis [UNKNOWN][IMP][TAS] detection of glucose [UNKNOWN][IMP][ISS] NADP metabolic process [UNKNOWN] glucose homeostasis [UNKNOWN][IMP][ISS] positive regulation of insulin secretion [UNKNOWN][IDA][ISS] negative regulation of epinephrine secretion [IMP] second-messenger-mediated signaling [IDA]
Molecular Function:	nucleotide binding [IEA] magnesium ion binding [IDA] glucose binding [UNKNOWN][IDA][IPI][ISS] ATP binding [UNKNOWN][IDA][ISS] protein binding [UNKNOWN][IMP][IPI] protein phosphatase binding [IPI] glucokinase activity [UNKNOWN][IDA][ISS] ADP binding [IDA] transferase activity [IEA] kinase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDDRARMEA TKKEKVEQIL AEFQLQEEDL KKVMSRMQKE MDRGLRLETH EEASVKMLPT  60
   61 YVRSTPEGSE VGDFLSLDLG GTNFRVMLVK VGEGEAGQWS VKTKHQMYSI PEDAMTGTAE 120
  121 MLFDYISECI SDFLDKHQMK HKKLPLGFTF SFPVRHEDLD KGILLNWTKG FKASGAEGNN 180
  181 IVGLLRDAIK RRGDFEMDVV AMVNDTVATM ISCYYEDRQC EVGMIVGTGC NACYMEEMQN 240
  241 VELVEGDEGR MCVNTEWGAF GDSGELDEFL LEYDRMVDES SANPGQQLYE KIIGGKYMGE 300
  301 LVRLVLLKLV DENLLFHGEA SEQLRTRGAF ETRFVSQVES DSGDRKQIHN ILSTLGLRPS 360
  361 VTDCDIVRRA CESVSTRAAH MCSAGLAGVI NRMRESRSED VMRITVGVDG SVYKLHPSFK 420
  421 ERFHASVRRL TPNCEITFIE SEEGSGRGAA LVSAVACKKA CMLAQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: HXK4_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: