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Protein Overview: PDK2_RAT

General Information:
Name(s) found: PDK2_RAT [Swiss-Prot]
Description(s) found:
Found 31 descriptions.
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  • [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial OS=Rattus norvegicus GN=Pdk2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 407 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IEA]
    pyruvate dehydrogenase complex [IDA]
    mitochondrial matrix [IEA]
    mitochondrion [UNKNOWN][IDA]
    [NOT]nucleolus [UNKNOWN]
    Biological Process: carbohydrate metabolic process [IEA]
    signal transduction [IEA]
    glucose metabolic process [IEA]
    protein amino acid phosphorylation [IDA][IMP]
    regulation of acetyl-CoA biosynthetic process from pyruvate [UNKNOWN]
    peptidyl-histidine phosphorylation [IEA]
    Molecular Function: two-component sensor activity [IEA]
    nucleotide binding [IEA]
    ATP binding [UNKNOWN][IDA][IMP]
    protein homodimerization activity [IDA]
    protein heterodimerization activity [IDA]
    pyruvate dehydrogenase (acetyl-transferring) kinase activity [IDA][IMP]
    transferase activity [IEA]
    protein complex binding [IDA]
    kinase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRWFRALLKN ASLAGAPKYI EHFSKFSPSP LSMKQFLDFG SSNACEKTSF TFLRQELPVR  60
   61 LANIMKEINL LPDRVLSTPS VQLVQSWYVQ SLLDIMEFLD KDPEDHRTLS QFTDALVTIR 120
  121 NRHNDVVPTM AQGVLEYKDT YGDDPVSNQN IQYFLDRFYL SRISIRMLIN QHTLIFDGST 180
  181 NPAHPKHIGS IDPNCSVSDV VKDAYDMAKL LCDKYYMASP DLEIQEVNAT NATQPIHMVY 240
  241 VPSHLYHMLF ELFKNAMRAT VESHESSLTL PPIKIMVALG EEDLSIKMSD RGGGVPLRKI 300
  301 ERLFSYMYST APTPQPGTGG TPLAGFGYGL PISRLYAKYF QGDLQLFSME GFGTDAVIYL 360
  361 KALSTDSVER LPVYNKSAWR HYQTIQEAGD WCVPSTEPKN TSTYRVS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..407] PSI-BLAST 64.522879 Pyruvate dehydrogenase kinase


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle