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Protein Overview: PRDX1_RAT

General Information:
Name(s) found: PRDX1_RAT [Swiss-Prot]
Description(s) found:
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  • pir||I52425 probable thioredoxin peroxidase (EC 1.11.1.-) HBP23 - rat [NCBI NR]
  • gi|56789700|gb|AAH88118.1| Peroxiredoxin 1 [Rattus norvegicus] [NCBI NR]
  • gi|34849851|gb|AAH58450.1| Peroxiredoxin 1 [Rattus norvegicus] [NCBI NR]
  • gi|2499470|sp|Q63716.1|PRDX1_RAT RecName: Full=Peroxiredoxin-1; AltName: Full=Thioredoxin peroxidase 2; AltName: Full=Thioredoxin-dependent peroxide reductase 2; AltName: Full=Heme-binding 23 kDa protein; AltName: Full=HBP23 [NCBI NR]
  • gi|16923958|ref|NP_476455.1| peroxiredoxin 1 [Rattus norvegicus] [NCBI NR]
  • gi|149035583|gb|EDL90264.1| rCG50201 [Rattus norvegicus] [NCBI NR]
  • gi|1060977|dbj|BAA06275.1| heme-binding 23 kDa protein (HBP23) [Rattus norvegicus] [NCBI NR]
  • Peroxiredoxin-1 OS=Rattus norvegicus GN=Prdx1 PE=1 SV=1 [Swiss-Prot]
  • (Q63716) Peroxiredoxin 1 (EC 1.11.1.-) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) (Heme-binding 23 kDa protein) (HBP23) [Swiss-Prot]
  • Ensembl_locations(Chr-bp):2-196386235;5-162516580 Peroxiredoxin 1 [hmr_yeast5_DM3-1_pombe.fasta]
  • peroxiredoxin 1 [HMR_022704-rand.fasta]
  • peroxiredoxin 1 [Rattus norvegicus]gi|34849851|gb|AAH58450.1| Peroxiredoxin 1 [Rattus norvegicus]gi|7432670|pir||I52425 probable thioredoxin peroxidase (EC 1.11.1.-) HBP23 - ratgi|1060977|dbj|BAA06275.1| heme-binding 23 kDa protein (HBP23) [Rattus norv [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Peroxiredoxin-1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • Tax_Id=10116 Peroxiredoxin 1 [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta]
  • (NM_057114) peroxiredoxin 1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • peroxiredoxin 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Peroxiredoxin-1 (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) (Heme-binding 23 kDa protein) (HBP23) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • rCG50201 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • heme-binding 23 kDa protein (HBP23) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Peroxiredoxin 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 PEROXIREDOXIN 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Prdx1 Peroxiredoxin-1 [rat-ipi-250309-contam.fasta]
  • Peroxiredoxin-1 OS=Rattus norvegicus GN=Prdx1 [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 199 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN]
    cytoplasm [IDA]
    mitochondrial matrix [IDA]
    melanosome [IEA]
    mitochondrion [UNKNOWN]
    nuclear euchromatin [IDA]
    cytosol [IDA]
    peroxisomal matrix [IDA]
    nucleolus [IDA]
    Biological Process: cell proliferation [UNKNOWN]
    response to oxidative stress [UNKNOWN][IDA]
    erythrocyte homeostasis [UNKNOWN]
    removal of superoxide radicals [UNKNOWN]
    regulation of stress-activated MAPK cascade [UNKNOWN]
    cell redox homeostasis [IEA]
    oxidation reduction [IEA]
    natural killer cell mediated cytotoxicity [UNKNOWN]
    response to reactive oxygen species [UNKNOWN]
    regulation of NF-kappaB import into nucleus [UNKNOWN]
    hydrogen peroxide catabolic process [UNKNOWN]
    Molecular Function: peroxidase activity [UNKNOWN][IEA]
    protein binding [UNKNOWN]
    protein homodimerization activity [IDA]
    oxidoreductase activity [IEA]
    thioredoxin peroxidase activity [UNKNOWN]
    heme binding [IPI]
    peroxiredoxin activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSGNAKIGH PAPSFKATAV MPDGQFKDIS LSDYKGKYVV FFFYPLDFTF VCPTEIIAFS  60
   61 DRAEEFKKLN CQVIGASVDS HFCHLAWINT PKKQGGLGPM NIPLVSDPKR TIAQDYGVLK 120
  121 ADEGISFRGL FIIDDKGILR QITINDLPVG RSVDEILRLV QAFQFTDKHG EVCPAGWKPG 180
  181 SDTIKPDVNK SKEYFSKQK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle