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Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity. Any process involved in the carrying out of an immune response by a lymphocyte. Any process that activates or increases the frequency, rate or extent of cell death by apoptosis. The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell. The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines. A process that directly activates any of the steps required for cell death by apoptosis. A process which directly activates any of the steps required for programmed cell death. The directed killing of a target cell by a leukocyte. Any process of the immune system that occurs as part of an immune response. Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity. Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity. The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: natural killer cell mediated cytotoxicity
Acc: GO:0042267
Aspect: Biological Process
Desc: The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
Synonyms:
  • natural killer-cell mediated cytolysis
  • NK cell mediated cell killing
  • natural killer cell mediated cytolysis
  • natural killer cell mediated cell death
  • NK cell mediated cytotoxicity
  • NK cell mediated cell death
  • killer activity
  • natural killer cell mediated cell killing
  • NK cell mediated cytolysis
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 69 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0042267 - natural killer cell mediated cytotoxicity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle