Protein Overview: CAN3_RAT

General Information:
Name(s) found:	CAN3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|B34488 calpain (EC 3.4.22.17) large chain 3 - rat [NCBI NR] gi\|8393041\|ref\|NP_058813.1\| calpain 3 [Rattus norvegicus] [NCBI NR] gi\|205956\|gb\|AAA41790.1\| p94 protein [NCBI NR] gi\|115586\|sp\|P16259.1\|CAN3_RAT RecName: Full=Calpain-3; AltName: Full=Calpain L3; AltName: Full=Calpain p94; AltName: Full=Calcium-activated neutral proteinase 3; Short=CANP 3; AltName: Full=Muscle-specific calcium-activated neutral protease 3 [NCBI NR] Calpain-3 OS=Rattus norvegicus GN=Capn3 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):3-100905238;3-100905238 Calpain 3 large subunit [hmr_yeast5_DM3-1_pombe.fasta] calpain 3 [HMR_022704-rand.fasta] calpain 3 [Rattus norvegicus]gi\|92046\|pir\|\|B34488 calpain (EC 3.4.22.17) large chain 3 - ratgi\|205956\|gb\|AAA41790.1\| p94 proteingi\|115586\|sp\|P16259\|CAN3_RAT Calpain 3 (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle- [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Calpain-3 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_017117) calpain 3 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Calpain 3 [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] Calpain-3 (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] calpain 3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] p94 protein [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 CALPAIN 3 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Capn3 Calpain-3 [rat-ipi-250309-contam.fasta] Calpain-3 OS=Rattus norvegicus GN=Capn3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	821 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [IDA] intracellular [IEA]
Biological Process:	myofibril assembly [UNKNOWN] response to drug [IEP] response to calcium ion [IDA] proteolysis [UNKNOWN][TAS] sarcomere organization [UNKNOWN][IEA]
Molecular Function:	protein binding [UNKNOWN][IPI] calcium ion binding [TAS] calcium-dependent cysteine-type endopeptidase activity [UNKNOWN][IDA][TAS] peptidase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTVISPTVA PRTGAEPRSP GPVPHPAQGK TTEAGGGHPG GIYSAIISRN FPIIGVKEKT  60
   61 FEQLHKKCLE KKVLYLDPEF PPDETSLFYS QKFPIQFVWK RPPEICENPR FIIGGANRTD 120
  121 ICQGDLGDCW LLAAIACLTL NERLLFRVIP HDQSFTENYA GIFHFQFWRY GDWVDVVIDD 180
  181 CLPTYNNQLV FTKSNHRNEF WSALLEKAYA KLHGSYEALK GGNTTEAMED FTGGVTEFFE 240
  241 IKDAPSDMYK IMRKAIERGS LMGCSIDDGT NMTYGTSPSG LNMGELIARM VRNMDNSLLR 300
  301 DSDLDPRASD DRPSRTIVPV QYETRMACGL VKGHAYSVTG LEEALFKGEK VKLVRLRNPW 360
  361 GQVEWNGSWS DGWKDWSFVD KDEKARLQHQ VTEDGEFWMS YDDFVYHFTK LEICNLTADA 420
  421 LESDKLQTWT VSVNEGRWVR GCSAGGCRNF PDTFWTNPQY RLKLLEEDDD PDDSEVICSF 480
  481 LVALMQKNRR KDRKLGANLF TIGFAIYEVP KEMHGNKQHL QKDFFLYNAS KARSKTYINM 540
  541 REVSQRFRLP PSEYVIVPST YEPHQEGEFI LRVFSEKRNL SEEAENTISV DRPVKKKKNK 600
  601 PIIFVSDRAN SNKELGVDQE AEEGKDKTGP DKQGESPQPR PGHTDQESEE QQQFRNIFRQ 660
  661 IAGDDMEICA DELKNVLNTV VNKHKDLKTQ GFTLESCRSM IALMDTDGSG RLNLQEFHHL 720
  721 WKKIKAWQKI FKHYDTDHSG TINSYEMRNA VNDAGFHLNS QLYDIITMRY ADKHMNIDFD 780
  781 SFICCFVRLE GMFRAFHAFD KDGDGIIKLN VLEWLQLTMY A

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: CAN3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: