Protein Overview: CP7B1_RAT

General Information:
Name(s) found:	CP7B1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|5921931\|sp\|Q63688.1\|CP7B1_RAT RecName: Full=25-hydroxycholesterol 7-alpha-hydroxylase; Short=Oxysterol 7-alpha-hydroxylase; AltName: Full=Cytochrome P450 7B1; AltName: Full=HCT-1 [NCBI NR] gi\|1226240\|gb\|AAA92616.1\| cytochrome P450 Cyp7b1 [Rattus norvegicus] [NCBI NR] (Q63688) Cytochrome P450 7B1 (Oxysterol 7-alpha-hydroxylase) (EC 1.14.13.-) (HCT-1) (Fragment) [Swiss-Prot] 25-hydroxycholesterol 7-alpha-hydroxylase (Fragment) OS=Rattus norvegicus GN=Cyp7b1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):2-105353189 Cytochrome P450 7B1 [hmr_yeast5_DM3-1_pombe.fasta] cytochrome P450 Cyp7b1 [Rattus norvegicus]gi\|5921931\|sp\|Q63688\|CP7B_RAT Cytochrome P450 7B1 (Oxysterol 7-alpha-hydroxylase) (HCT-1) [nrdb_11152004_Chlamydomonas] Cytochrome P450 7B1 (25-hydroxycholesterol 7-alpha-hydroxylase) (Oxysterol 7-alpha-hydroxylase) (HCT-1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cytochrome P450 Cyp7b1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 25-hydroxycholesterol 7-alpha-hydroxylase (Fragment) OS=Rattus norvegicus GN=Cyp7b1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	414 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [UNKNOWN][IEA] membrane [IEA] microsome [IEA] endoplasmic reticulum [IEA] cellular_component [ND]
Biological Process:	prostate gland epithelium morphogenesis [UNKNOWN][IEA] response to drug [IEP] cholesterol metabolic process [TAS] steroid metabolic process [IEA] negative regulation of estrogen receptor signaling pathway [UNKNOWN][IEA] response to cAMP [IEP] oxidation reduction [IEA] bile acid biosynthetic process [TAS] circadian rhythm [IDA] memory [IDA] positive regulation of epithelial cell proliferation [UNKNOWN][IEA]
Molecular Function:	oxysterol 7-alpha-hydroxylase activity [UNKNOWN][TAS] metal ion binding [IEA] electron carrier activity [IEA] 25-hydroxycholesterol 7alpha-hydroxylase activity [IEA] monooxygenase activity [IEA] heme binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALEYQYVMKN PKQLSFEKFS RRLSAKAFSV KKLLTNDDLS NDIHRGYLLL QGKSLDGLLE  60
   61 TMIQEVKEIF ESRLLKLTDW NTARVFDFCS SLVFEITFTT IYGKILAANK KQIISELRDD 120
  121 FLKFDDHFPY LVSDIPIQLL RNAEFMQKKI IKCLTPEKVA QMQRRSEIVQ ERQEMLKKYY 180
  181 GHEEFEIGAH HLGLLWASLA NTIPAMFWAM YYLLQHPEAM EVLRDEIDSF LQSTGQKKGP 240
  241 GISVHFTREQ LDSLVCLESA ILEVLRLCSY SSIIREVQED MDFSSESRSY RLRKGDFVAV 300
  301 FPPMIHNDPE VFDAPKDFRF DRFVEDGKKK TTFFKGGKKL KSYIIPFGLG TSKCPGRYFA 360
  361 INEMKLLVII LLTYFDLEVI DTKPIGLNHS RMFLGIQHPD SDISFRYKAK SWRS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.48

Protein Overview: CP7B1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: