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Protein Overview: CP7B1_RAT

General Information:
Name(s) found: CP7B1_RAT [Swiss-Prot]
Description(s) found:
Found 9 descriptions.
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  • 25-hydroxycholesterol 7-alpha-hydroxylase (Fragment) OS=Rattus norvegicus GN=Cyp7b1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 414 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum membrane [UNKNOWN][IEA]
    membrane [IEA]
    microsome [IEA]
    endoplasmic reticulum [IEA]
    cellular_component [ND]
    Biological Process: prostate gland epithelium morphogenesis [UNKNOWN][IEA]
    response to drug [IEP]
    cholesterol metabolic process [TAS]
    steroid metabolic process [IEA]
    negative regulation of estrogen receptor signaling pathway [UNKNOWN][IEA]
    response to cAMP [IEP]
    oxidation reduction [IEA]
    bile acid biosynthetic process [TAS]
    circadian rhythm [IDA]
    memory [IDA]
    positive regulation of epithelial cell proliferation [UNKNOWN][IEA]
    Molecular Function: oxysterol 7-alpha-hydroxylase activity [UNKNOWN][TAS]
    metal ion binding [IEA]
    electron carrier activity [IEA]
    25-hydroxycholesterol 7alpha-hydroxylase activity [IEA]
    monooxygenase activity [IEA]
    heme binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALEYQYVMKN PKQLSFEKFS RRLSAKAFSV KKLLTNDDLS NDIHRGYLLL QGKSLDGLLE  60
   61 TMIQEVKEIF ESRLLKLTDW NTARVFDFCS SLVFEITFTT IYGKILAANK KQIISELRDD 120
  121 FLKFDDHFPY LVSDIPIQLL RNAEFMQKKI IKCLTPEKVA QMQRRSEIVQ ERQEMLKKYY 180
  181 GHEEFEIGAH HLGLLWASLA NTIPAMFWAM YYLLQHPEAM EVLRDEIDSF LQSTGQKKGP 240
  241 GISVHFTREQ LDSLVCLESA ILEVLRLCSY SSIIREVQED MDFSSESRSY RLRKGDFVAV 300
  301 FPPMIHNDPE VFDAPKDFRF DRFVEDGKKK TTFFKGGKKL KSYIIPFGLG TSKCPGRYFA 360
  361 INEMKLLVII LLTYFDLEVI DTKPIGLNHS RMFLGIQHPD SDISFRYKAK SWRS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.48

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle