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Protein Overview: AVR2A_RAT

General Information:
Name(s) found: AVR2A_RAT [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • Activin receptor type-2A OS=Rattus norvegicus GN=Acvr2a PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 513 amino acids

    Gene Ontology:
    Cellular Component: inhibin-betaglycan-ActRII complex [UNKNOWN][IEA]
    cytoplasm [UNKNOWN][IEA]
    activin receptor complex [TAS]
    membrane [IEA]
    integral to membrane [IEA]
    plasma membrane [UNKNOWN]
    Biological Process: Sertoli cell proliferation [UNKNOWN][IEA]
    sperm ejaculation [UNKNOWN][IEA]
    male gonad development [UNKNOWN]
    spermatogenesis [UNKNOWN][IEA]
    mesoderm development [UNKNOWN][IEA]
    anterior/posterior pattern formation [UNKNOWN][IEA]
    protein amino acid phosphorylation [TAS]
    positive regulation of osteoblast differentiation [UNKNOWN][IEA]
    embryonic skeletal system development [UNKNOWN][IEA]
    positive regulation of erythrocyte differentiation [UNKNOWN][IEA]
    determination of left/right symmetry [UNKNOWN][IEA]
    penile erection [UNKNOWN][IEA]
    gastrulation with mouth forming second [UNKNOWN][IEA]
    BMP signaling pathway [UNKNOWN]
    positive regulation of protein amino acid phosphorylation [UNKNOWN][IEA]
    positive regulation of activin receptor signaling pathway [UNKNOWN][IEA]
    regulation of nitric-oxide synthase activity [UNKNOWN][IEA]
    regulation of BMP signaling pathway [UNKNOWN][IEA]
    positive regulation of bone mineralization [UNKNOWN][IEA]
    Molecular Function: coreceptor activity [UNKNOWN][IEA]
    growth factor binding [UNKNOWN][IEA]
    protein self-association [UNKNOWN][IEA]
    transmembrane receptor protein serine/threonine kinase activity [TAS]
    nucleotide binding [IEA]
    ATP binding [IEA]
    inhibin beta-B binding [IDA]
    inhibin beta-A binding [UNKNOWN][IDA]
    protein binding [UNKNOWN]
    activin binding [UNKNOWN][IDA][TAS]
    metal ion binding [IEA]
    activin receptor activity, type II [IDA]
    activin receptor activity [UNKNOWN]
    transferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGAAAKLAFA VFLISCSSGA ILGRSETQEC LFFNANWERD RTNQTGVEPC YGDKDKRRHC  60
   61 FATWKNISGS IEIVKQGCWL DDINCYDRTD CIEKKDSPEV YFCCCEGNMC NEKFSYFPEM 120
  121 EVTQPTSNPV TPKPPYYNIL LYSLVPLMLI AGIVICAFWV YRHHMMAYPP VLVPTQDPGP 180
  181 PPPSPLLGLK PLQLLEVKAR GRFGCVWKAQ LLNEYVAVKI FPIQDKQSWQ NEYEVYSLPG 240
  241 MKHENILQFI GAEKRGTSVD VDLWLITAFH EKGSLSDFLK ANVVSWNELC HIAETMARGL 300
  301 AYLHEDIPGL KDGHKPAISH RDIKSKNVLL KNNLTACIAD FGLALKFEAG KSGGDTHGQV 360
  361 GTRRYMAPEV LEGAINFQRD AFLRIDMYAM GLVLWELASR CTAADGPVDE YMLPFEEEIG 420
  421 QHPSLEDMQE VVVHKKKRPV LRDYWQKHAG MAMLCETIEE CWDHDAEARL SAGCLGERIT 480
  481 QMQRLTNIIT TEDIVTVVTM VTNVDFPPKE SSL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle