Protein Overview: ASIC2_RAT

General Information:
Name(s) found:	ASIC2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|77404415\|ref\|NP_001029186.1\| amiloride-sensitive cation channel 1, neuronal isoform b [Rattus norvegicus] [NCBI NR] gi\|2500841\|sp\|Q62962.1\|ACCN1_RAT RecName: Full=Amiloride-sensitive cation channel 1, neuronal; AltName: Full=Amiloride-sensitive brain sodium channel; AltName: Full=Amiloride-sensitive brain sodium channel 2; AltName: Full=Amiloride-sensitive cation chann [NCBI NR] gi\|149053616\|gb\|EDM05433.1\| amiloride-sensitive cation channel 1, neuronal (degenerin), isoform CRA_b [Rattus norvegicus] [NCBI NR] gi\|1280441\|gb\|AAC52588.1\| degenerin channel MDEG [NCBI NR] (Q62962) Amiloride-sensitive cation channel 1, neuronal (Amiloride-sensitive brain sodium channel) (Brain sodium channel 1) (BNaC1) (Amiloride-sensitive cation channel neuronal 1) (BNC1) (Degenerin channel MDEG) [Swiss-Prot] Acid-sensing ion channel 2 OS=Rattus norvegicus GN=Asic2 PE=1 SV=1 [Swiss-Prot] Amiloride-sensitive cation channel 1, neuronal OS=Rattus norvegicus GN=Accn1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):10-66739808 Amiloride-sensitive brain sodium channel BNaC1 [hmr_yeast5_DM3-1_pombe.fasta] Amiloride-sensitive cation channel 1, neuronal (Amiloride-sensitive brain sodium channel) (Brain sodium channel 1) (BNaC1) (Amiloride-sensitive cation channel neuronal 1) (BNC1) (Degenerin channel MDEG)gi\|1280441\|gb\|AAC52588.1\| degenerin channel MDEG [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Amiloride-sensitive cation channel 1, neuronal [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012892) amiloride-sensitive cation channel 1, neuronal (degenerin), two different splice products: MDEG1 and MDEG2 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Amiloride-sensitive cation channel 1, neuronal [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] amiloride-sensitive cation channel 1, neuronal isoform b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Amiloride-sensitive cation channel 1, neuronal (Amiloride-sensitive brain sodium channel) (Amiloride-sensitive brain sodium channel 2) (Amiloride-sensitive cation channel neuronal 1) (Acid-sensing ion channel 2) (Brain sodium channel 1) (BNaC1) (BNC1) (Ma [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] amiloride-sensitive cation channel 1, neuronal (degenerin), isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] degenerin channel MDEG [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 AMILORIDE-SENSITIVE CATION CHANNEL 1, NEURONAL [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] amiloride-sensitive cation channel 1, neuronal (degenerin) isoform b [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Accn1 Isoform 1 of Amiloride-sensitive cation channel 1, neuronal [rat-ipi-250309-contam.fasta] Isoform 1 of Amiloride-sensitive cation channel 1, neuronal OS=Rattus norvegicus GN=Accn1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	512 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [UNKNOWN] integral to membrane [UNKNOWN][IEA] neuronal cell body [UNKNOWN] neuron projection [UNKNOWN] plasma membrane [IEA]
Biological Process:	response to acid [UNKNOWN][IMP] sensory perception of sound [UNKNOWN] sodium ion transport [UNKNOWN][IDA] cation transport [UNKNOWN][TAS] negative regulation of apoptosis [UNKNOWN] sensory perception of sour taste [TAS] sensory perception of pain [IPI] phototransduction [UNKNOWN] response to mechanical stimulus [UNKNOWN] detection of mechanical stimulus involved in sensory perception [UNKNOWN]
Molecular Function:	ion channel activity [IEA] protein binding [UNKNOWN] cation channel activity [UNKNOWN] amiloride-sensitive sodium channel activity [UNKNOWN][IMP] voltage-gated sodium channel activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLKESPSEG SLQPSSIQIF ANTSTLHGIR HIFVYGPLTI RRVLWAVAFV GSLGLLLVES  60
   61 SERVSYYFSY QHVTKVDEVV AQSLVFPAVT LCNLNGFRFS RLTTNDLYHA GELLALLDVN 120
  121 LQIPDPHLAD PTVLEALRQK ANFKHYKPKQ FSMLEFLHRV GHDLKDMMLY CKFKGQECGH 180
  181 QDFTTVFTKY GKCYMFNSGE DGKPLLTTVK GGTGNGLEIM LDIQQDEYLP IWGETEETTF 240
  241 EAGVKVQIHS QSEPPFIQEL GFGVAPGFQT FVATQEQRLT YLPPPWGECR SSEMGLDFFP 300
  301 VYSITACRID CETRYIVENC NCRMVHMPGD APFCTPEQHK ECAEPALGLL AEKDSNYCLC 360
  361 RTPCNLTRYN KELSMVKIPS KTSAKYLEKK FNKSEKYISE NILVLDIFFE ALNYETIEQK 420
  421 KAYEVAALLG DIGGQMGLFI GASLLTILEL FDYIYELIKE KLLDLLGKEE EEGSHDENMS 480
  481 TCDTMPNHSE TISHTVNVPL QTALGTLEEI AC

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ASIC2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: