Protein Overview: CD5R1_RAT

General Information:
Name(s) found:	CD5R1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|48428803\|sp\|P61810.1\|CD5R1_RAT RecName: Full=Cyclin-dependent kinase 5 activator 1; Short=CDK5 activator 1; AltName: Full=Cyclin-dependent kinase 5 regulatory subunit 1; AltName: Full=Tau protein kinase II 23 kDa subunit; Short=p23; AltName: Full=TPKII [NCBI NR] gi\|16758762\|ref\|NP_446343.1\| cyclin-dependent kinase 5, regulatory subunit 1 [Rattus norvegicus] [NCBI NR] gi\|149053608\|gb\|EDM05425.1\| cyclin-dependent kinase 5, regulatory subunit 1 (p35) [Rattus norvegicus] [NCBI NR] gi\|1255170\|gb\|AAC52611.1\| P35 [NCBI NR] (P61810) Cyclin-dependent kinase 5 activator 1 precursor (CDK5 activator 1) (Cyclin-dependent kinase 5 regulatory subunit 1) (Tau protein kinase II 23 kDa subunit) (TPKII regulatory subunit) (p23) (p25) (p35) [Swiss-Prot] Cyclin-dependent kinase 5 activator 1 OS=Rattus norvegicus GN=Cdk5r1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):10-66091183 Cyclin-dependent kinase 5 activator 1 precursor [hmr_yeast5_DM3-1_pombe.fasta] cyclin-dependent kinase 5, regulatory subunit 1 [HMR_022704-rand.fasta] cyclin-dependent kinase 5, regulatory subunit (p35) 1 [Mus musculus]gi\|16758762\|ref\|NP_446343.1\| cyclin-dependent kinase 5, regulatory subunit 1 [Rattus norvegicus]gi\|29747961\|gb\|AAH50768.1\| Cyclin-dependent kinase 5, regulatory subunit (p35) 1 [Mus mus [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Cyclin-dependent kinase 5 activator 1 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_053891) cyclin-dependent kinase 5, regulatory subunit 1 (p35) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] cyclin-dependent kinase 5, regulatory subunit 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Cyclin-dependent kinase 5 activator 1 precursor (CDK5 activator 1) (Cyclin-dependent kinase 5 regulatory subunit 1) (Tau protein kinase II 23 kDa subunit) (p23) (TPKII regulatory subunit) [Contains: Cyclin-dependent kinase 5 activator 1, p35 (p35); Cyclin [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cyclin-dependent kinase 5, regulatory subunit 1 (p35) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] P35 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 CYCLIN-DEPENDENT KINASE 5 ACTIVATOR 1 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Cyclin-dependent kinase 5 activator 1 precursor (CDK5 activator 1) (Cyclin-dependent kinase 5 regulatory subunit 1) (Tau protein kinase II 23 kDa subunit) (TPKII regulatory subunit) (p23) (p25) (p35) [Contains: Cyclin-dependent kinase 5 activator 1, p35; [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Cdk5r1 Cyclin-dependent kinase 5 activator 1 [rat-ipi-250309-contam.fasta] Cyclin-dependent kinase 5 activator 1 OS=Rattus norvegicus GN=Cdk5r1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	307 amino acids
Gene Ontology:
Cellular Component:	neuronal cell body [IDA] plasma membrane [IEA] growth cone [IDA] nucleus [IDA] dendrite [IDA] contractile fiber [IDA] perinuclear region of cytoplasm [IEA] cytoplasm [IDA] membrane [IDA] dendritic spine [IDA] neuromuscular junction [IDA] cyclin-dependent protein kinase 5 holoenzyme complex [IDA][TAS] axon [IDA]
Biological Process:	embryonic development [IDA] neuron differentiation [IDA] neuron projection development [IMP] neuron cell-cell adhesion [ISS] muscarinic acetylcholine receptor signaling pathway [IDA] axon guidance [ISS] brain development [ISS] protein amino acid phosphorylation [IDA] positive regulation of neuron apoptosis [IDA] axonal fasciculation [ISS] neuron migration [ISS] axon extension [TAS] ionotropic glutamate receptor signaling pathway [IDA]
Molecular Function:	protein binding [UNKNOWN][IDA][IPI] protein serine/threonine kinase activator activity [IDA] calcium ion binding [IDA] cadherin binding [IDA] cyclin-dependent protein kinase activity [IDA] kinase activity [IDA] cyclin-dependent protein kinase 5 activator activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTVLSLSPS YRKATLFEDG AATVGHYTAV QNSKNAKDKN LKRHSIISVL PWKRIVAVSA  60
   61 KKKNSKKAQP NSSYQSNIAH LNNENLKKSL SCANLSTFAQ PPPAQPPAPP ASQLSGSQTG 120
  121 VSSSVKKAPH PAITSAGTPK RVIVQASTSE LLRCLGEFLC RRCYRLKHLS PTDPVLWLRS 180
  181 VDRSLLLQGW QDQGFITPAN VVFLYMLCRD VISSEVGSDH ELQAVLLTCL YLSYSYMGNE 240
  241 ISYPLKPFLV ESCKEAFWDR CLSVINLMSS KMLQINADPH YFTQVFSDLK NESGQEDKKR 300
  301 LLLGLDR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: CD5R1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: