Protein Overview: RUNX2_RAT

General Information:
Name(s) found:	RUNX2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|21362908\|sp\|Q9Z2J9.2\|RUNX2_RAT RecName: Full=Runt-related transcription factor 2; AltName: Full=Core-binding factor subunit alpha-1; Short=CBF-alpha-1; AltName: Full=Osteoblast-specific transcription factor 2; Short=OSF-2 [NCBI NR] Runt-related transcription factor 2 (Fragments) OS=Rattus norvegicus GN=Runx2 PE=2 SV=2 [Swiss-Prot] (Q9Z2J9) Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Osteoblast-specific transcription factor 2) (OSF-2) (Fragments) [Swiss-Prot] Ensembl_locations(Chr-bp):9-19414992 Runt-related transcription factor 2 [hmr_yeast5_DM3-1_pombe.fasta] Tax_Id=10116 Runt-related transcription factor 2 (Fragment) [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Runt-related transcription factor 2 [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Osteoblast-specific transcription factor 2) (OSF-2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 RUNT-RELATED TRANSCRIPTION FACTOR 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Runx2 Runt-related transcription factor 2 (Fragment) [rat-ipi-250309-contam.fasta] Runt-related transcription factor 2 (Fragments) OS=Rattus norvegicus GN=Runx2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	218 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA][IEA] transcription factor complex [UNKNOWN] cytoplasm [UNKNOWN] [NOT]nucleolus [UNKNOWN]
Biological Process:	regulation of fibroblast growth factor receptor signaling pathway [UNKNOWN] positive regulation of cell proliferation [UNKNOWN] osteoblast fate commitment [UNKNOWN] chondrocyte differentiation [UNKNOWN] chondrocyte development [UNKNOWN] regulation of transcription, DNA-dependent [IEA] odontogenesis of dentine-containing tooth [UNKNOWN] cell maturation [UNKNOWN] regulation of odontogenesis of dentine-containing tooth [UNKNOWN] positive regulation of osteoblast differentiation [UNKNOWN] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN] negative regulation of smoothened signaling pathway [UNKNOWN] regulation of osteoblast differentiation [TAS] positive regulation of ossification [IMP] skeletal system development [UNKNOWN] positive regulation of transcription, DNA-dependent [IDA] negative regulation of transcription [UNKNOWN] osteoblast differentiation [UNKNOWN] endochondral ossification [UNKNOWN] positive regulation of chondrocyte differentiation [UNKNOWN] regulation of ossification [UNKNOWN]
Molecular Function:	DNA binding [UNKNOWN] ATP binding [IEA] transcription factor activity [IDA][IEA][TAS] protein binding [UNKNOWN] chromatin binding [UNKNOWN] transcription factor binding [IPI] transcription activator activity [UNKNOWN][IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLHSPHKQPQ NHKCGANFLQ EDSKEALVFK WLISAGHYQP PRPTESVSAL STVHAVIFKA  60
   61 ASSIYNRGHK FYLEKKGGTM ASNSLFSAVT PCQQSFFWNK TLPVAFKVVA LGEVPDGTVV 120
  121 TVMAGNDENY SAELRNASAV MKNQVARFND LRFVGRSGRG KSFTLTITVF TNPPQVATYH 180
  181 RAIKVTVDGP REPRRHRQKL DDSKPSLFSD RLSDLGRI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: RUNX2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: