Protein Overview: CREB1_RAT

General Information:
Name(s) found:	CREB1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|S03343 cAMP response element-binding protein - rat [NCBI NR] gi\|56005\|emb\|CAA32890.1\| unnamed protein product [Rattus norvegicus] [NCBI NR] gi\|226280\|prf\|\|1504306A cAMP regulated nuclear factor CREB [NCBI NR] gi\|149045986\|gb\|EDL98879.1\| cAMP responsive element binding protein 1, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|13591924\|ref\|NP_112279.1\| cAMP responsive element binding protein 1 isoform B [Rattus norvegicus] [NCBI NR] gi\|117435\|sp\|P15337.1\|CREB1_RAT RecName: Full=Cyclic AMP-responsive element-binding protein 1; Short=cAMP-responsive element-binding protein 1; Short=CREB-1 [NCBI NR] (P15337) cAMP response element binding protein (CREB) [Swiss-Prot] Cyclic AMP-responsive element-binding protein 1 OS=Rattus norvegicus GN=Creb1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):9-68962719;18-64902091 Splice isoform 1 of P15337 [hmr_yeast5_DM3-1_pombe.fasta] cAMP responsive element binding protein 1 isoform B; cAMP response element binding protein 1 [HMR_022704-rand.fasta] cAMP responsive element binding protein 1 isoform B [Rattus norvegicus]gi\|56005\|emb\|CAA32890.1\| unnamed protein product [Rattus norvegicus]gi\|92049\|pir\|\|S03343 cAMP response element-binding protein - ratgi\|117435\|sp\|P15337\|CREB_RAT cAMP response elemen [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of cAMP response element-binding protein [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Splice Isoform 1 of cAMP response element binding protein [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_031017) cAMP response element binding protein 1, isoform B [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] cAMP responsive element binding protein 1 isoform B [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cAMP response element-binding protein (CREB) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cAMP responsive element binding protein 1, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cAMP regulated nuclear factor CREB [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF CAMP RESPONSE ELEMENT BINDING PROTEIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Creb1 Isoform 1 of cAMP response element-binding protein [rat-ipi-250309-contam.fasta] Isoform 1 of Cyclic AMP-responsive element-binding protein 1 OS=Rattus norvegicus GN=Creb1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	341 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA][IEA][TAS] transcription factor complex [UNKNOWN][IDA][IMP] mitochondrion [IDA] chromatin [IDA] nucleoplasm [UNKNOWN]
Biological Process:	response to organic substance [UNKNOWN][IEA] regulation of cell size [UNKNOWN][IEA] transforming growth factor beta receptor signaling pathway [IMP] regulation of transcription, DNA-dependent [UNKNOWN][IEA] transcription from RNA polymerase II promoter [IMP] positive regulation of hormone secretion [UNKNOWN][IEA] lactation [UNKNOWN][IEA] regulation of apoptosis [IDA] protein amino acid phosphorylation [UNKNOWN][IEA] regulation of circadian rhythm [IMP] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IDA] positive regulation of multicellular organism growth [UNKNOWN][IEA] pituitary gland development [UNKNOWN][IEA] mammary gland development [UNKNOWN] axonogenesis [UNKNOWN][IEA] response to drug [UNKNOWN][IEA] positive regulation of transforming growth factor-beta3 production [IMP] positive regulation of gene-specific transcription from RNA polymerase II promoter [IMP]
Molecular Function:	DNA binding [UNKNOWN] transcription factor activity [UNKNOWN][IEA][IMP][TAS] protein binding [UNKNOWN][IPI] specific RNA polymerase II transcription factor activity [IMP] RNA polymerase II transcription factor activity, enhancer binding [IDA] double-stranded DNA binding [IDA] sequence-specific DNA binding [IDA][IEA] protein dimerization activity [IEA] transcription factor binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTMDSGADNQ QSGDAAVTEA ESQQMTVQAQ PQIATLAQVS MPAAHATSSA PTVTLVQLPN  60
   61 GQTVQVHGVI QAAQPSVIQS PQVQTVQSSC KDLKRLFSGT QISTIAESED SQESVDSVTD 120
  121 SQKRREILSR RPSYRKILND LSSDAPGVPR IEEEKSEEET SAPAITTVTV PTPIYQTSSG 180
  181 QYIAITQGGA IQLANNGTDG VQGLQTLTMT NAAATQPGTT ILQYAQTTDG QQILVPSNQV 240
  241 VVQAASGDVQ TYQIRTAPTS TIAPGVVMAS SPALPTQPAE EAARKREVRL MKNREAAREC 300
  301 RRKKKEYVKC LENRVAVLEN QNKTLIEELK ALKDLYCHKS D

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: CREB1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: