Protein Overview: LYRIC_RAT

General Information:
Name(s) found:	LYRIC_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|56748899\|sp\|Q9Z1W6.2\|LYRIC_RAT RecName: Full=Protein LYRIC; AltName: Full=Lysine-rich CEACAM1 co-isolated protein; AltName: Full=Metastasis adhesion protein; Short=Metadherin [NCBI NR] gi\|19173758\|ref\|NP_596889.1\| metadherin [Rattus norvegicus] [NCBI NR] gi\|15100185\|gb\|AAC72405.2\| LYRIC [Rattus norvegicus] [NCBI NR] Protein LYRIC OS=Rattus norvegicus GN=Mtdh PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):7-95531020 LYRIC [hmr_yeast5_DM3-1_pombe.fasta] LYRIC [HMR_022704-rand.fasta] LYRIC [Rattus norvegicus]gi\|19173758\|ref\|NP_596889.1\| LYRIC [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Protein LYRIC [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Splice Isoform 1 of LYRIC protein [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_133398) LYRIC [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (Metastasis adhesion protein) (Metadherin) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] metadherin [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] LYRIC [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 LYRIC [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Mtdh Isoform 1 of Protein LYRIC [rat-ipi-250309-contam.fasta] Isoform 1 of Protein LYRIC OS=Rattus norvegicus GN=Mtdh [011711_HMR.fasta] Protein LYRIC OS=Rattus norvegicus GN=Mtdh PE=2 SV=2 [20141208_RAT.fasta]
Organism:	Rattus norvegicus
Length:	581 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [IEA] nucleus [UNKNOWN][IEA] tight junction [IPI] nuclear membrane [UNKNOWN][IEA] perinuclear region of cytoplasm [UNKNOWN][ISS] cytoplasm [IEA] membrane [IEA] integral to membrane [IEA] cell junction [IEA] endoplasmic reticulum [UNKNOWN][ISS] nucleolus [UNKNOWN][IEA]
Biological Process:	negative regulation of transcription from RNA polymerase II promoter [UNKNOWN][ISS] positive regulation of NF-kappaB transcription factor activity [UNKNOWN][ISS]
Molecular Function:	NF-kappaB binding [UNKNOWN][ISS] protein binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAARSWQDEL AQQAEEGSAR LRELLSVGLG FLRTELGLDL GLEPKRYPSW VILVGTGALG  60
   61 LLLLFLLGYG WAAACAGARK KRRSPPRKRE EVTPPTPAPE DPAQLKNLRS EEQKKKNRKK 120
  121 LPEKPKPNGR TVEIPEDEVV RTPRSITAKQ PPETDKKNEK SKKNKKKSKS DAKAVQNSSR 180
  181 HDGKEVDEGA WETKISHREK RQQRKRDKVL TDSGSLDSTI PGIENTITVT TEQLTTASFP 240
  241 VGSKKNKGDS HLNVQVSNFK SGKGDSTLQV SSGLNENITV NGGGWSEKSV KLSSQLSAGE 300
  301 EKWNSVPPAS AGKRKTEQSA WTQDPGDTNA NGKDWGRNWS DRSIFSGIGS TAEPVSQSTT 360
  361 SDYQWDGSRN QPHIDDEWSG LNGLSSADPS SDWNAPAEEW GNWVDEDRAS LLKSQEPISN 420
  421 DQKDSDDDKE KGEGALPTGK SKKKKKKKKK QGEDNSITQD TEDLEKDTRE ELPVNTSKAR 480
  481 PKQEKACSLK TMSTSDPVEV LIKNSQPIKT LPPAISAEPS VTLSKGDSDK SSSQVPPMLQ 540
  541 DTDKPKSNAK QNSVPPSQTK SETNWESPKQ IKKKKKARRE T

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: LYRIC_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: