Protein Overview: FGD4_RAT

General Information:
Name(s) found:	FGD4_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|61213042\|sp\|O88387.1\|FGD4_RAT RecName: Full=FYVE, RhoGEF and PH domain-containing protein 4; AltName: Full=Actin filament-binding protein frabin; AltName: Full=FGD1-related F-actin-binding protein [NCBI NR] gi\|3342246\|gb\|AAC27698.1\| actin-filament binding protein Frabin [Rattus norvegicus] [NCBI NR] gi\|21245110\|ref\|NP_640356.1\| FGD1-related F-actin-binding protein [Rattus norvegicus] [NCBI NR] gi\|149019708\|gb\|EDL77856.1\| FYVE, RhoGEF and PH domain containing 4, isoform CRA_c [Rattus norvegicus] [NCBI NR] FYVE, RhoGEF and PH domain-containing protein 4 OS=Rattus norvegicus GN=Fgd4 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):11-5902 Actin-filament binding protein Frabin [hmr_yeast5_DM3-1_pombe.fasta] FGD1-related F-actin-binding protein; actin-filament binding protein frabin [HMR_022704-rand.fasta] FGD1-related F-actin-binding protein [Rattus norvegicus]gi\|3342246\|gb\|AAC27698.1\| actin-filament binding protein Frabin [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 FYVE, RhoGEF and PH domain-containing protein 4 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 FYVE, RhoGEF and PH domain containing protein 4 [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_139263) actin-filament binding protein frabin [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament-binding protein frabin) (FGD1-related F-actin-binding protein) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] FGD1-related F-actin-binding protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] FYVE, RhoGEF and PH domain containing 4, isoform CRA_c [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] actin-filament binding protein Frabin [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 ACTIN-FILAMENT BINDING PROTEIN FRABIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Fgd4 FYVE, RhoGEF and PH domain-containing protein 4 [rat-ipi-250309-contam.fasta] FYVE, RhoGEF and PH domain-containing protein 4 OS=Rattus norvegicus GN=Fgd4 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	766 amino acids
Gene Ontology:
Cellular Component:	cytoskeleton [IEA] cytoplasm [IEA] cytosol [UNKNOWN] filopodium [UNKNOWN][IEA] intracellular [IEA] lamellipodium [UNKNOWN][IEA]
Biological Process:	regulation of cell shape [IMP] regulation of Rho protein signal transduction [IEA] apoptosis [UNKNOWN] activation of JUN kinase activity [IDA][IMP] lamellipodium assembly [UNKNOWN][IEA] microspike assembly [UNKNOWN][IEA] induction of apoptosis by extracellular signals [UNKNOWN]
Molecular Function:	actin filament binding [IMP] zinc ion binding [IEA] actin binding [IDA] metal ion binding [IEA] guanyl-nucleotide exchange factor activity [UNKNOWN][IEA] Rho guanyl-nucleotide exchange factor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEESNPAPTS CASKGKHSKV SDLISHFEGG SVLSSYTDVQ KDSTMNLNIP QTPRQHGLTS  60
   61 TTPQKLPSHK SPQKQEKDSD QNQGQHGCLA NGVAAAQSQM ECETEKEAAL SPETDTQTAA 120
  121 ASPDAHVLNG VRNETTTDSA SSVTNSHDEN ACDSSCRTQG TDLGLPSKEG EPVIEAELQE 180
  181 RENGLSTEGL NPLDQHHEVK ETNEQKLHKI ATELLLTERA YVSRLNLLDQ VFYCKLLEEA 240
  241 NRGSFPAEMV NKIFSNISSI NAFHSKFLLP ELEKRMQEWE TTPRIGDILQ KLAPFLKMYG 300
  301 EYVKGFDNAV ELVKNMTERV PQFKSVTEEI QKQKICGSLT LQHHMLEPIQ RIPRYEMLLK 360
  361 DYLKKLSPDA PDWNDAKKSL EIISTAASHS NSAIRKMENL KKLLEIYEML GEEEDIVNPS 420
  421 NELIKEGQIL KLAARNTSAQ ERYLFLFNNM LLYCVPRFSL VGSKFTVRTR VGIDGMKIVE 480
  481 THNEEYPHTF QVSGKERTLE LQASSEQDKE EWIKALQESI DAFHQRHETF RNAIAKENDI 540
  541 PLEVSTAELG KRAPRWIRDN EVTMCMKCKE SFNALTRRRH HCRACGHVVC WKCSDYKAQL 600
  601 EYDGGRLNKV CKDCYQIMSG FAESEEKKRR GILEIESAEV SGNSEVCSFL QYMEKSKPWQ 660
  661 KIWCVIPKQD PLVLYMYGAP QDVRAQATIP LLGYIVDDMP KSADLPHSFK LTQSKSVHSF 720
  721 AADSEELKQK WLKIILLAVT GETPDGPSEH LDTLDNLPGP KEKSEC

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: FGD4_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: