Protein Overview: C11B1_RAT

General Information:
Name(s) found:	C11B1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|77917600\|ref\|NP_036669.2\| cytochrome P450, family 11, subfamily B, polypeptide 1 [Rattus norvegicus] [NCBI NR] gi\|55994\|emb\|CAA33472.1\| precursor polypeptide (AA -8 - 491) [Rattus norvegicus] [NCBI NR] pir\|\|A46039 steroid 11beta-monooxygenase (EC 1.14.15.4) cytochrome P450 11B1 precursor - rat [NCBI NR] gi\|303796\|dbj\|BAA01957.1\| cytochrome P-450-11beta [Rattus norvegicus] [NCBI NR] gi\|303770\|dbj\|BAA03171.1\| steroid 11-beta-monooxygenase [Rattus norvegicus] [NCBI NR] gi\|117266\|sp\|P15393.1\|C11B1_RAT RecName: Full=Cytochrome P450 11B1, mitochondrial; AltName: Full=CYPXIB1; AltName: Full=P450C11; AltName: Full=Steroid 11-beta-hydroxylase; AltName: Full=P450(11 beta)-DS; Flags: Precursor [NCBI NR] (P15393) Cytochrome P450 11B1, mitochondrial precursor (EC 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) (P450(11 beta)-DS) [Swiss-Prot] Cytochrome P450 11B1, mitochondrial OS=Rattus norvegicus GN=Cyp11b1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):7_random-1982248 Cytochrome P450 11B1, mitochondrial precursor [hmr_yeast5_DM3-1_pombe.fasta] precursor polypeptide (AA -8 - 491) [Rattus norvegicus]gi\|303770\|dbj\|BAA03171.1\| steroid 11-beta-monooxygenase [Rattus norvegicus]gi\|303796\|dbj\|BAA01957.1\| cytochrome P-450-11beta [Rattus norvegicus]gi\|424024\|pir\|\|A46039 steroid 11beta-monooxygenase (E [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Cytochrome P450 11B1, mitochondrial precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012539) cytochrome P450, subfamily XIB gene cluster [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Cytochrome P450 11B1, mitochondrial precursor (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) (P450(11 beta)-DS) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cytochrome P450, subfamily 11B, polypeptide 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cytochrome P-450-11beta [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] precursor polypeptide (AA -8 - 491) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] steroid 11-beta-monooxygenase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 CYTOCHROME P450 11B1, MITOCHONDRIAL PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] cytochrome P450, family 11, subfamily B, polypeptide 1 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Cytochrome P450 11B1, mitochondrial OS=Rattus norvegicus GN=Cyp11b1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	499 amino acids
Gene Ontology:
Cellular Component:	mitochondrial membrane [IEA] mitochondrion [UNKNOWN][IDA] membrane [IEA] integral to endoplasmic reticulum membrane [IDA]
Biological Process:	glucocorticoid biosynthetic process [UNKNOWN] cortisol biosynthetic process [UNKNOWN] steroid metabolic process [TAS] aldosterone biosynthetic process [UNKNOWN] oxidation reduction [IEA] steroid biosynthetic process [UNKNOWN][IDA] glucocorticoid metabolic process [TAS] C21-steroid hormone biosynthetic process [UNKNOWN] regulation of blood pressure [UNKNOWN]
Molecular Function:	metal ion binding [IEA] electron carrier activity [IEA] corticosterone 18-monooxygenase activity [UNKNOWN] steroid 11-beta-monooxygenase activity [UNKNOWN][IDA] steroid binding [IDA] monooxygenase activity [IEA] heme binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALRVTADVW LARPWQCLHR TRALGTTAKV APKTLKPFEA IPQYSRNKWL KMIQILREQG  60
   61 QENLHLEMHQ AFQELGPIFR HSAGGAQIVS VMLPEDAEKL HQVESILPHR MPLEPWVAHR 120
  121 ELRGLRRGVF LLNGADWRFN RLQLNPNMLS PKAIQSFVPF VDVVARDFVE NLKKRMLENV 180
  181 HGSMSINIQS NMFNYTMEAS HFVISGERLG LTGHDLKPES VTFTHALHSM FKSTTQLMFL 240
  241 PKSLTRWTST RVWKEHFDSW DIISEYVTKC IKNVYRELAE GRQQSWSVIS EMVAQSTLSM 300
  301 DAIHANSMEL IAGSVDTTAI SLVMTLFELA RNPDVQQALR QESLAAEASI VANPQKAMSD 360
  361 LPLLRAALKE TLRLYPVGSF VERIVHSDLV LQNYHVPAGT FVIIYLYSMG RNPAVFPRPE 420
  421 RYMPQRWLER KRSFQHLAFG FGVRQCLGRR LAEVEMLLLL HHMLKTFQVE TLRQEDMQMV 480
  481 FRFLLMPSSS PFLTFRPVS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.82

Protein Overview: C11B1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: