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Protein Overview: GNAS3_RAT

General Information:
Name(s) found: GNAS3_RAT [Swiss-Prot]
Description(s) found:
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  • gi|81865018|sp|Q792G6.1|GNAS3_RAT RecName: Full=Neuroendocrine secretory protein 55; Short=NESP55; Contains: RecName: Full=LHAL tetrapeptide; Contains: RecName: Full=GPIPIRRH peptide [NCBI NR]
  • gi|7532782|gb|AAF63227.1|AF105254_1 neuroendocrine secretory protein 55 [Rattus norvegicus] [NCBI NR]
  • gi|4206778|gb|AAD11803.1| neuroendocrine-specific Golgi protein p55 [Rattus norvegicus] [NCBI NR]
  • gi|4206775|gb|AAD11801.1| neuroendocrine-specific Golgi protein p55 [Rattus norvegicus] [NCBI NR]
  • Neuroendocrine secretory protein 55 OS=Rattus norvegicus GN=Gnas PE=2 SV=1 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):None Neuroendocrine-specific golgi protein P55 isoform 1 [hmr_yeast5_DM3-1_pombe.fasta]
  • guanine nucleotide binding protein alpha stimulating isoform d [Mus musculus]gi|7532782|gb|AAF63227.1| neuroendocrine secretory protein 55 [Rattus norvegicus]gi|4206782|gb|AAD11805.1| neuroendocrine-specific Golgi protein p55 isoform 1 [Mus musculus]gi [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Neuroendocrine secretory protein 55 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • neuroendocrine secretory protein 55 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • neuroendocrine-specific Golgi protein p55 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 NEUROENDOCRINE SECRETORY PROTEIN 55 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Gnas Neuroendocrine secretory protein 55 [rat-ipi-250309-contam.fasta]
  • Isoform Nesp55 of Neuroendocrine secretory protein 55 OS=Rattus norvegicus GN=Gnas [011711_HMR.fasta]
  • Isoform of Q63803, Neuroendocrine secretory protein 55 OS=Rattus norvegicus GN=Gnas PE=2 SV=1 [RAT.fasta.20160308]
    • Organism: Rattus norvegicus
    Length: 256 amino acids

    Gene Ontology:
    Cellular Component: synaptic vesicle [IEA]
    synapse [IEA]
    extracellular region [IEA]
    intracellular part [IDA]
    plasma membrane [UNKNOWN][IDA]
    membrane fraction [UNKNOWN][IDA]
    endosome [IDA]
    heterotrimeric G-protein complex [IDA]
    cytoplasm [UNKNOWN][IDA]
    sarcolemma [IDA]
    ruffle [IEA]
    cell junction [IEA]
    cytoplasmic vesicle [IEA]
    vesicle [IDA]
    intrinsic to membrane [UNKNOWN]
    trans-Golgi network membrane [UNKNOWN]
    Biological Process: activation of adenylate cyclase activity by dopamine receptor signaling pathway [UNKNOWN]
    G-protein coupled receptor protein signaling pathway [IEA][IMP]
    signal transduction [IEA]
    post-embryonic body morphogenesis [UNKNOWN]
    post-embryonic development [UNKNOWN]
    energy reserve metabolic process [UNKNOWN]
    embryonic cranial skeleton morphogenesis [UNKNOWN]
    activation of adenylate cyclase activity by G-protein signaling pathway [UNKNOWN][IDA]
    positive regulation of osteoblast differentiation [UNKNOWN]
    hormone-mediated signaling pathway [UNKNOWN]
    skeletal system development [UNKNOWN]
    positive regulation of osteoclast differentiation [UNKNOWN]
    response to drug [UNKNOWN]
    endochondral ossification [UNKNOWN]
    embryonic hindlimb morphogenesis [UNKNOWN]
    cartilage development [UNKNOWN]
    Molecular Function: nucleotide binding [IEA]
    GTP binding [IEA][TAS]
    identical protein binding [UNKNOWN]
    protein binding [UNKNOWN]
    guanyl nucleotide binding [IEA]
    signal transducer activity [IDA][IEA]
    mu-type opioid receptor binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRRSRAHQW RRARHNYNDL CPPIGRRAAT ALLWLSCSIA LLRALASSNA RAQQRAAQRR  60
   61 SFLNAHHRSA AAAAAAQVLP ESSESESDHE HEEAEPELAR PECLEYDQDD YETETDSETE 120
  121 PESDIQSETE FETEPETEPE TAPTTEPETE PEDERGPRGA TFNQSLTQRL HALKLQSADA 180
  181 SPRRAQPTTQ EPESASEGEE PQREPLDEDP RDPEESEERR EANRQPRRCK TRRPARRRDQ 240
  241 SPESPPRKGP IPIRRH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..135] Pfam 36.853872 No description for PF06390.3 was found. No confident structure predictions are available.
    2 View Details [136..256] FFAS03 1.04 No description for 2j63A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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