Protein Overview: SLIT3_RAT

General Information:
Name(s) found:	SLIT3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|T13953 MEGF5 protein - rat [NCBI NR] gi\|45477220\|sp\|O88280.1\|SLIT3_RAT RecName: Full=Slit homolog 3 protein; Short=Slit-3; AltName: Full=Multiple epidermal growth factor-like domains 5; Flags: Precursor [NCBI NR] gi\|3449292\|dbj\|BAA32461.1\| MEGF5 [Rattus norvegicus] [NCBI NR] gi\|13786142\|ref\|NP_112611.1\| slit homolog 3 [Rattus norvegicus] [NCBI NR] (O88280) Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5) [Swiss-Prot] Slit homolog 3 protein OS=Rattus norvegicus GN=Slit3 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):10-18628522;10-18734223 MEGF5 [hmr_yeast5_DM3-1_pombe.fasta] slit homolog 3; slit (Drosophila) homolog 3 [HMR_022704-rand.fasta] slit homolog 3 [Rattus norvegicus]gi\|45477220\|sp\|O88280\|SLT3_RAT Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5)gi\|7514008\|pir\|\|T13953 MEGF5 protein - ratgi\|3449292\|dbj\|BAA32461.1\| MEGF5 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Slit homolog 3 protein precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_031321) slit homolog 3; slit (Drosophila) homolog 3 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] slit homolog 3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] MEGF5 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SLIT HOMOLOG 3 PROTEIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Slit3 Slit homolog 3 protein [rat-ipi-250309-contam.fasta] Slit homolog 3 protein OS=Rattus norvegicus GN=Slit3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1523 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] extracellular space [UNKNOWN][IEA] mitochondrion [IDA] extracellular region [IEA]
Biological Process:	Roundabout signaling pathway [UNKNOWN] negative chemotaxis [UNKNOWN] [NOT]chemorepulsion involved in embryonic olfactory bulb interneuron migration [UNKNOWN] multicellular organismal development [IEA] negative regulation of cell proliferation [UNKNOWN] nervous system development [UNKNOWN][IEA] axon guidance [UNKNOWN][IEA] brain development [IEP] organ morphogenesis [UNKNOWN][IEA] spinal cord development [IEP] axon extension involved in axon guidance [UNKNOWN] luteolysis [UNKNOWN][IEA] negative regulation of gene expression [UNKNOWN] negative regulation of chemokine-mediated signaling pathway [UNKNOWN] negative regulation of cell growth [UNKNOWN] cell differentiation [IEA] cellular response to hormone stimulus [UNKNOWN][IEA] response to cortisol stimulus [UNKNOWN][IEA]
Molecular Function:	Roundabout binding [UNKNOWN][IEA] protein binding [IEA] calcium ion binding [IEA] molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPGRTGAGA AVRARLALAL ALASILSGPP AAACPTKCTC SAASVDCHGL GLRAVPRGIP  60
   61 RNAERLDLDR NNITRITKMD FTGLKNLRVL HLEDNQVSVI ERGAFQDLKQ LERLRLNKNK 120
  121 LQVLPELLFQ STPKLTRLDL SENQIQGIPR KAFRGVTGVK NLQLDNNHIS CIEDGAFRAL 180
  181 RDLEILTLNN NNISRILVTS FNHMPKIRTL RLHSNHLYCD CHLAWLSDWL RQRRTIGQFT 240
  241 LCMAPVHLRG FSVADVQKKE YVCPGPHSEA PACNANSLSC PSACSCSNNI VDCRGKGLTE 300
  301 IPANLPEGIV EIRLEQNSIK SIPAGAFIQY KKLKRIDISK NQISDIAPDA FQGLKSLTSL 360
  361 VLYGNKITEI PKGLFDGLVS LQLLLLNANK INCLRVNTFQ DLQNLNLLSL YDNKLQTISK 420
  421 GLFAPLQSIQ TLHLAQNPFV CDCHLKWLAD YLQDNPIETS GARCSSPRRL ANKRISQIKS 480
  481 KKFRCSGSED YRNRFSSECF MDLVCPEKCR CEGTIVDCSN QKLSRIPSHL PEYTTDLRLN 540
  541 DNDIAVLEAT GIFKKLPNLR KINLSNNRIK EVREGAFDGA AGVQELMLTG NQLETMHGRM 600
  601 FRGLSGLKTL MLRSNLISCV NNDTFAGLSS VRLLSLYDNR ITTISPGAFT TLVSLSTINL 660
  661 LSNPFNCNCH MAWLGRWLRK RRIVSGNPRC QKPFFLKEIP IQDVAIQDFT CEGNEENSCQ 720
  721 LSPRCPEQCT CVETVVRCSN RGLHTLPKGM PKDVTELYLE GNHLTAVPKE LSTFRQLTLI 780
  781 DLSNNSISML TNHTFSNMSH LSTLILSYNR LRCIPVHAFN GLRSLRVLTL HGNDISSVPE 840
  841 GSFNDLTSLS HLALGINPLH CDCSLRWLSE WIKAGYKEPG IARCSSPESM ADRLLLTTPT 900
  901 HRFQCKGPVD INIVAKCNAC LSSPCKNNGT CSQDPVEQYR CTCPYSYKGK DCTVPINTCV 960
  961 QNPCQHGGTC HLSESHRDGF SCSCPLGFEG QRCEINPDDC EDNDCENSAT CVDGINNYAC1020
 1021 VCPPNYTGEL CDEVIDYCVP EMNLCQHEAK CISLDKGFRC ECVPGYSGKL CETDNDDCVA1080
 1081 HKCRHGAQCV DAVNGYTCIC PQGFSGLFCE HPPPMVLLQT SPCDQYECQN GAQCIVVQQE1140
 1141 PTCRCPPGFA GPRCEKLITV NFVGKDSYVE LASAKVRPQA NISLQVATDK DNGILLYKGD1200
 1201 NDPLALELYQ GHVRLVYDSL SSPPTTVYSV ETVNDGQFHS VELVMLNQTL NLVVDKGAPK1260
 1261 SLGKLQKQPA VGINSPLYLG GIPTSTGLSA LRQGADRPLG GFHGCIHEVR INNELQDFKA1320
 1321 LPPQSLGVSP GCKSCTVCRH GLCRSVEKDS VVCECHPGWT GPLCDQEAQD PCLGHSCSHG1380
 1381 TCVATGNSYV CKCAEGYEGP LCDQKNDSAN ACSAFKCHHG QCHISDRGEP YCLCQPGFSG1440
 1441 NHCEQENPCL GEIVREAIRR QKDYASCATA SKVPIMVCRG GCGSQCCQPI RSKRRKYVFQ1500
 1501 CTDGSSFVEE VERHLECGCR ECS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: SLIT3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: