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The signaling process whereby signaling from the receptor ROBO is brought to an end, rather than being reversibly modulated. The process whereby a SLIT protein causes activation of the receptor, Roundabout (ROBO). The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms. Any process that modulates the frequency, rate or extent of the Roundabout signaling pathway. The series of molecular signals generated by binding of a SLIT protein to a Roundabout (ROBO) family receptor on the surface of the target cell. Any process that activates or increases the frequency, rate or extent of the Roundabout signaling pathway. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell. Any process that stops, prevents or reduces the frequency, rate or extent of the Roundabout signaling pathway.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: Roundabout signaling pathway
Acc: GO:0035385
Aspect: Biological Process
Desc: The series of molecular signals generated by binding of a SLIT protein to a Roundabout (ROBO) family receptor on the surface of the target cell.
Synonyms:
  • ROBO/SLIT signaling pathway
  • ROBO signaling pathway
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0035385 - Roundabout signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle