Protein Overview: JIP1_RAT

General Information:
Name(s) found:	JIP1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|5051883\|gb\|AAD38350.1\| JIP-1b [Rattus norvegicus] [NCBI NR] gi\|17432932\|sp\|Q9R237.2\|JIP1_RAT RecName: Full=C-jun-amino-terminal kinase-interacting protein 1; Short=JNK-interacting protein 1; Short=JIP-1; AltName: Full=JNK MAP kinase scaffold protein 1; AltName: Full=Islet-brain-1; Short=IB-1; AltName: Full=Mitogen [NCBI NR] C-Jun-amino-terminal kinase-interacting protein 1 OS=Rattus norvegicus GN=Mapk8ip1 PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):None Splice isoform 1 of Q9R237 [hmr_yeast5_DM3-1_pombe.fasta] C-jun-amino-terminal kinase interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1) (JIP-1 related protein) (JRP)gi\|5051883\|gb\|AAD3835 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of C-jun-amino-terminal kinase-interacting protein 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Splice Isoform 1 of C-jun-amino-terminal kinase interacting protein 1 [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1) (JIP-1-related protein) (JRP) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] JIP-1b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF C-JUN-AMINO-TERMINAL KINASE INTERACTING PROTEIN 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Mapk8ip1 Isoform 1 of C-jun-amino-terminal kinase-interacting protein 1 [rat-ipi-250309-contam.fasta] Isoform 1 of C-Jun-amino-terminal kinase-interacting protein 1 OS=Rattus norvegicus GN=Mapk8ip1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	708 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] perinuclear region of cytoplasm [IDA] cytoplasm [UNKNOWN][IDA] membrane [IEA] cytosol [IDA] neuron projection [UNKNOWN][IEA]
Biological Process:	vesicle-mediated transport [UNKNOWN][IEA] anti-apoptosis [UNKNOWN][IDA] signal transduction [UNKNOWN][IDA][TAS] negative regulation of JUN kinase activity [IMP] regulation of transcription, DNA-dependent [UNKNOWN][IEA] negative regulation of JNK cascade [IMP] JUN phosphorylation [UNKNOWN][IEA] regulation of JNK cascade [ISS]
Molecular Function:	protein kinase binding [UNKNOWN][ISS] protein binding [UNKNOWN][IEA] kinesin binding [UNKNOWN][ISS] JUN kinase binding [IPI] MAP-kinase scaffold activity [UNKNOWN][IMP] mitogen-activated protein kinase kinase kinase binding [IPI] mitogen-activated protein kinase kinase binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAERESGLSG GAASPPAASP FLGLHIASPP NFRLTHDISL EEFEDEDLSE ITDECGISLQ  60
   61 CKDTLSLRPP RAGLLSAGSS GSAGSRLQAE MLQMDLIDAA SDTPGAEDDE EDDDELAAQR 120
  121 PGVGPSKAES GQEPASRSQG QGQGPGTGSG DTYRPKRPTT LNLFPQVPRS QDTLNNNSLG 180
  181 KKHSWQDRVS RSSSPLKTGE QTPPHEHICL SDELPPQGSP VPTQDRGTST DSPCRRTAAT 240
  241 QMAPPSGPPA TAPGGRGHSH RDRIHYQADV RLEATEEIYL TPVQRPPDPA EPTSTFLPPT 300
  301 ESRMSVSSDP DPAAYSVTAG RPHPSISEED EGFDCLSSPE QAEPPGGGWR GSLGEPPPPP 360
  361 RASLSSDTSA LSYDSVKYTL VVDEHAQLEL VSLRPCFGDY SDESDSATVY DNCASASSPY 420
  421 ESAIGEEYEE APQPRPPTCL SEDSTPDEPD VHFSKKFLNV FMSGRSRSSS AESFGLFSCV 480
  481 INGEEHEQTH RAIFRFVPRH EDELELEVDD PLLVELQAED YWYEAYNMRT GARGVFPAYY 540
  541 AIEVTKEPEH MAALAKNSDW IDQFRVKFLG SVQVPYHKGN DVLCAAMQKI ATTRRLTVHF 600
  601 NPPSSCVLEI SVRGVKIGVK ADEAQEAKGN KCSHFFQLKN ISFCGYHPKN NKYFGFITKH 660
  661 PADHRFACHV FVSEDSTKAL AESVGRAFQQ FYKQFVEYTC PTEDIYLE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.60

Protein Overview: JIP1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: