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Protein Overview: MAP1B_RAT

General Information:
Name(s) found: MAP1B_RAT [Swiss-Prot]
Description(s) found:
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  • gi|19856246|sp|P15205.2|MAP1B_RAT RecName: Full=Microtubule-associated protein 1B; Short=MAP-1B; AltName: Full=Neuraxin; Contains: RecName: Full=MAP1 light chain LC1 [NCBI NR]
  • (P15205) Microtubule-associated protein 1B (MAP 1B) (Neuraxin) [Contains: MAP1 light chain LC1] [Swiss-Prot]
  • Microtubule-associated protein 1B OS=Rattus norvegicus GN=Map1b PE=1 SV=2 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):2-27668471 Microtubule-associated protein 1B [hmr_yeast5_DM3-1_pombe.fasta]
  • Microtubule-associated protein 1B (MAP 1B) (Neuraxin) [Contains: MAP1 light chain LC1] [nrdb_11152004_Chlamydomonas]
  • Microtubule-associated protein 1B OS=Rattus norvegicus GN=Map1b [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 2459 amino acids

    Gene Ontology:
    Cellular Component: postsynaptic density [IDA]
    neuronal cell body [IDA]
    perikaryon [IDA]
    microtubule associated complex [IDA]
    plasma membrane [IDA]
    microtubule [IEA]
    growth cone [IDA]
    dendrite [IDA]
    soluble fraction [IDA]
    cytoskeleton [IDA]
    perinuclear region of cytoplasm [IDA]
    cytosol [UNKNOWN][IEA]
    axon [IDA]
    Biological Process: embryonic development [IEP]
    nervous system development [IEP]
    response to wounding [IEP]
    positive regulation of neuron differentiation [IMP]
    response to axon injury [IEP]
    response to mechanical stimulus [IEP]
    response to insecticide [IEP]
    response to inorganic substance [IEP]
    positive regulation of microtubule polymerization [IDA]
    response to protein stimulus [IEP]
    dendrite development [UNKNOWN][IEA]
    axon regeneration in the peripheral nervous system [IEP]
    response to carbohydrate stimulus [IEP]
    negative regulation of microtubule depolymerization [IDA]
    developmental maturation [IEP]
    positive regulation of axon extension [IMP]
    neuron development [IEP]
    response to peptide hormone stimulus [IEP]
    synapse assembly [IEP]
    microtubule bundle formation [UNKNOWN][IDA]
    central nervous system development [IEP]
    response to drug [IEP]
    response to estradiol stimulus [IEP]
    induction of synaptic plasticity by chemical substance [IEP]
    response to vitamin A [IEP]
    response to nutrient levels [IEP]
    Molecular Function: protein binding [UNKNOWN][IPI]
    actin binding [IDA]
    phospholipid binding [IPI]
    protein complex binding [IDA]
    microtubule binding [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATVVVEATE PEPSGSIGNP AATTSPSLSH RFLDSKFYLL VVVGETVTEE HLRRAIGNIE  60
   61 LGIRSWETNL IECNLDQELK LFVSRHSARF SPEVPGQKIL HHRSDVLETV VLINPSDEAV 120
  121 STEVRLMITD AARHKLLVLT GQCFENTGEL ILQSGSFSFQ NFIEIFTDQE IGELLSTTHP 180
  181 ANKASLTLFC PEEGDWKNSN LDRHNLQDFI NIKLNSASIL PEMEGLSEFT EYLSESVEVP 240
  241 SPFDILEPPT SGGFLKLSKP CCYIFPGGRG DSALFAVNGF NMLINGGSER KSCFWKLIRH 300
  301 LDRVDSILLT HIGDDNLPGI NSMLQRKIAE LEEESQGSTS NSDWMKNLIS PDLGVVFLNV 360
  361 PENLKNPEPN IKMKRSTEEA CFTLQYLNKL SMKPEPLFRS VGNAIEPVIL FQKMGVGKLK 420
  421 MYVLNPVKSS KEMQYFMQQW TGTNKDKAEL ILPNGQEVDI PISYLASVSS LIVWHPANPA 480
  481 EKIIRVLFPG NSTQYNILEG LEKLKHLDFL KQPLATQKDL TGQVSTPPVK QVKLKQRADS 540
  541 RESLKPATKP LSSKSVRKES KEEAPEATKA SQVEKTPKVE SKEKVIVKKD KPGKVESKPS 600
  601 VTEKEVPSKE EQSPVKAEVA EKAATESKPK VTKDKVVKKE IKTKPEEKKE EKPKKEVAKK 660
  661 EDKTPLKKDE KPKKEEAKKE IKKEIKKEEK KELKKEVKKE TPLKDAKKEV KKDEKKEVKK 720
  721 EEKEPKKEIK KISKDIKKST PLSDTKKPAA LKPKVAKKEE PTKKEPIAAG KLKDKGKVKV 780
  781 IKKEGKTTEA AATAVGTAAV AAAAGVAASG PAKELEAERS LMSSPEDLTK DFEELKAEEI 840
  841 DVAKDIKPQL ELIEDEEKLK ETEPGEAYVI QKETEVSKGS AESPDEGITT TEGEGECEQT 900
  901 PEELEPVEKQ GVDDIEKFED EGAGFEESSE AGDYEEKAET EEAEEPEEDG EDNVSGSASK 960
  961 HSPTEDEEIA KAEADVHIKE KRESVASGDD RAEEDMDEAL EKGEAEQSEE EGEEEEDKAE1020
 1021 DAREEDHEPD KTEAEDYVMA VVDKAAEAGV TEDQYDFLGT PAKQPGVQSP SREPASSIHD1080
 1081 ETLPGGSESE ATASDEENRE DQPEEFTATS GYTQSTIEIS SEPTPMDEMS TPRDVMTDET1140
 1141 NNEETESPSQ EFVNITKYES SLYSQEYSKP VVASFNGLSD GSKTDATDGR DYNASASTIS1200
 1201 PPSSMEEDKF SKSALRDAYR PEETDVKTGA ELDIKDVSDE RLSPAKSPSL SPSPPSPIEK1260
 1261 TPLGERSVNF SLTPNEIKAS AEGEATAVVS PGVTQAVVEE HCASPEEKTL EVVSPSQSVT1320
 1321 GSAGHTPYYQ SPTDEKSSHL PTEVTENAQA VPVSFEFTEA KDENERSSIS PMDEPVPDSE1380
 1381 SPIEKVLSPL RSPPLIGSES AYEDFLSADD KALGRRSESP FEGKNGKQGF SDKESPVSDL1440
 1441 TSDLYQDKQE EKRAGFIPIK EDFSPEKKAS DAEIMSSQSA LALDERKLGG DGSPTQVDVS1500
 1501 QFGSFKEDTK MSISEGTVSD KSATPVDEGA EDTYSHMEGV ASVSTASVAT SSFPEPTTDD1560
 1561 VSPSLHAEVG SPHSTEVDDS LSVSVVQTPT TFQETEMSPS KEECPRPMSI SPPDFSPKTA1620
 1621 KSRTPVQDHR SEQSSMSIEF GQESPEHSLA MDFSRQSPDH PTVGAGMLHI TENGPTEVDY1680
 1681 SPSDIQDSSL SHKIPPTEEP SYTQDNDLSE LISVSQVEAS PSTSSAHTPS QIASPLQEDT1740
 1741 LSDVVPPRDM SLYASLASEK VQSLEGEKLS PKSDISPLTP RESSPTYSPG FSDSTSGAKE1800
 1801 STAAYQTSSS PPIDAAAAEP YGFRSSMLFD TMQHHLALSR DLTTSSVEKD NGGKTPGDFN1860
 1861 YAYQKPESTT ESPDEEDYDY ESHEKTIQAH DVGGYYYEKT ERTIKSPCDS GYSYETIEKT1920
 1921 TKTPEDGGYS CEITEKTTRT PEEGGYSYEI SEKTTRTPEV SGYTYEKTER SRRLLDDISN1980
 1981 GYDDTEDGGH TLGDCSYSYE TTEKITSFPE SESYSYETTT KTTRSPDTSA YCYETMEKIT2040
 2041 KTPQASTYSY ETSDRCYTPE RKSPSEARQD VDLCLVSSCE FKHPKTELSP SFINPNPLEW2100
 2101 FAGEEPTEES ERPLTQSGGA PPPSGGKQQG RQCDETPPTS VSESAPSQTD SDVPPETEEC2160
 2161 PSITADANLD SEDESETIPT DKTVTYKHMD PPPAPMQDRS PSPRHPDVSM VDPEALAIEQ2220
 2221 NLGKALKKDL KEKAKTKKPG TKTKSSSPVK KGDGKSKPSA ASPKPGALKE SSDKVSRVAS2280
 2281 PKKKESVEKA MKTTTTPEVK ATRGEEKDKE TKNAANASAS KSVKTATAGP GTTKTAKSST2340
 2341 VPPGLPVYLD LCYIPNHSNS KNVDVEFFKR VRSSYYVVSG NDPAAEEPSR AVLDALLEGK2400
 2401 AQWGSNMQVT LIPTHDSEVM REWYQETHEK QQDLNIMVLA SSSTVVMQDE SFPACKIEL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle