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Protein Overview: 2ABB_RAT

General Information:
Name(s) found: 2ABB_RAT [Swiss-Prot]
Description(s) found:
Found 20 descriptions.
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  • Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform OS=Rattus norvegicus GN=Ppp2r2b PE=1 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 443 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [IDA]
    cytoskeleton [IDA]
    cytoplasm [IDA]
    mitochondrion [IDA]
    membrane [IEA]
    cytosol [IDA]
    protein phosphatase type 2A complex [IDA][IEA]
    mitochondrial outer membrane [IDA][IEA]
    Biological Process: protein targeting to mitochondrion [IMP]
    negative regulation of mitochondrial fusion [IMP]
    signal transduction [IEA]
    spermatid development [IEP]
    neuron differentiation [IEP]
    apoptosis [IEA]
    cellular response to stress [IEP]
    brain development [IEP]
    regulation of protein phosphatase type 2A activity [IDA]
    positive regulation of neuron apoptosis [IDA]
    mitochondrial fission [IDA]
    Molecular Function: protein binding [IPI]
    protein complex binding [IDA]
    protein phosphatase type 2A regulator activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEDIDTRKI NNSFLRDHSY ATEADIISTV EFNHTGELLA TGDKGGRVVI FQREQESKNQ  60
   61 VHRRGEYNVY STFQSHEPEF DYLKSLEIEE KINKIRWLPQ QNAAYFLLST NDKTVKLWKV 120
  121 SERDKRPEGY NLKDEEGRLR DPATITTLRV PVLRPMDLMV EATPRRVFAN AHTYHINSIS 180
  181 VNSDYETYMS ADDLRINLWN FEITNQSFNI VDIKPANMEE LTEVITAAEF HPHHCNTFVY 240
  241 SSSKGTIRLC DMRASALCDR HTKFFEEPED PSNRSFFSEI ISSISDVKFS HSGRYIMTRD 300
  301 YLTAKVWDLN MENRPVETYQ VHDYLRSKLC SLYENDCIFD KFECVWNGSD SVIMTGSYNN 360
  361 FFRMFDRNTK RDVTLEASRE NSKPRAILKP RKVCVGGKRR KDEISVDSLD FSKKILHTAW 420
  421 HPSENIIAVA ATNNLYIFQD KVN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle