Protein Overview: IL12A_RAT

General Information:
Name(s) found:	IL12A_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|5764659\|gb\|AAD51364.1\|AF177031_1 interleukin 12 p35 subunit [Rattus norvegicus] [NCBI NR] gi\|46576205\|sp\|Q9R103.1\|IL12A_RAT RecName: Full=Interleukin-12 subunit alpha; Short=IL-12A; AltName: Full=IL-12 subunit p35; AltName: Full=Cytotoxic lymphocyte maturation factor 35 kDa subunit; Short=CLMF p35; Flags: Precursor [NCBI NR] gi\|16758120\|ref\|NP_445842.1\| interleukin 12a [Rattus norvegicus] [NCBI NR] Interleukin-12 subunit alpha OS=Rattus norvegicus GN=Il12a PE=2 SV=1 [Swiss-Prot] (Q9R103) Interleukin-12 alpha chain precursor (IL-12A) (Cytotoxic lymphocyte maturation factor 35 kDa subunit) (CLMF p35) [Swiss-Prot] Ensembl_locations(Chr-bp):2-150595553 Interleukin 12 p35 subunit [hmr_yeast5_DM3-1_pombe.fasta] interleukin 12 p35 subunit [HMR_022704-rand.fasta] interleukin 12 p35 subunit [Rattus norvegicus]gi\|46576205\|sp\|Q9R103\|I12A_RAT Interleukin-12 alpha chain precursor (IL-12A) (Cytotoxic lymphocyte maturation factor 35 kDa subunit) (CLMF p35)gi\|5764659\|gb\|AAD51364.1\| interleukin 12 p35 subunit [Rattus nor [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Interleukin-12 alpha chain precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_053390) interleukin 12 p35 subunit [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Interleukin-12 subunit alpha precursor (IL-12A) (IL-12 subunit p35) (Cytotoxic lymphocyte maturation factor 35 kDa subunit) (CLMF p35) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] interleukin 12a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] interleukin 12 p35 subunit [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 INTERLEUKIN-12 ALPHA CHAIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Interleukin-12 alpha chain precursor (IL-12A) (Cytotoxic lymphocyte maturation factor 35 kDa subunit) (CLMF p35) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Il12a Interleukin-12 subunit alpha [rat-ipi-250309-contam.fasta] Interleukin-12 subunit alpha OS=Rattus norvegicus GN=Il12a [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	215 amino acids
Gene Ontology:
Cellular Component:	extracellular space [UNKNOWN] extracellular region [IEA] interleukin-12 complex [UNKNOWN][IEA]
Biological Process:	cell cycle arrest [UNKNOWN][IEA] positive regulation of smooth muscle cell apoptosis [UNKNOWN][IEA] positive regulation of T cell proliferation [UNKNOWN][IEA] positive regulation of tyrosine phosphorylation of Stat4 protein [UNKNOWN][IEA] positive regulation of cell adhesion [UNKNOWN][IEA] response to virus [UNKNOWN][IEA] positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [UNKNOWN][IEA] defense response to protozoan [UNKNOWN] positive regulation of natural killer cell mediated cytotoxicity [UNKNOWN] immune response [IEA] positive regulation of lymphocyte proliferation [UNKNOWN] positive regulation of natural killer cell activation [UNKNOWN][IEA] positive regulation of interferon-gamma production [UNKNOWN][IEA] negative regulation of smooth muscle cell proliferation [UNKNOWN][IEA] response to lipopolysaccharide [UNKNOWN][IEA] positive regulation of T cell mediated cytotoxicity [UNKNOWN][IEA] cell migration [UNKNOWN][IEA] response to UV-B [UNKNOWN][IEA] defense response to Gram-positive bacterium [UNKNOWN][IEA]
Molecular Function:	growth factor activity [UNKNOWN][IEA] protein binding [UNKNOWN][IEA] protein heterodimerization activity [UNKNOWN][IEA] interleukin-12 beta subunit binding [UNKNOWN][IEA] interleukin-12 receptor binding [IEA] cytokine activity [UNKNOWN][IDA] interleukin-27 binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCQSRYLLFL ATLVLLNHLT SARVIPVSGP AKCLNQSQNL LKTTDDMVRT AREKLKHYSC  60
   61 TAGDIDHEDI TRDKTSTLEA CLPLELHKNE SCLATKETSS IIRGSCLPPQ KTSLMMTLCL 120
  121 GSIYEDLKMY QSEFQAINAA LQSHNHQQIT LDRNMLMAID ELMRSLNHSG ETLHQKAPMG 180
  181 EADPYRVKMK LCILLHAFST RVMTINRVMN YLSSS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: IL12A_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: