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Protein Overview: EDN1_RAT

General Information:
Name(s) found: EDN1_RAT [Swiss-Prot]
Description(s) found:
Found 18 descriptions.
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  • Endothelin-1 OS=Rattus norvegicus GN=Edn1 PE=1 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 202 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [UNKNOWN][IDA]
    cytoplasm [UNKNOWN][IEA]
    extracellular region [IEA]
    Biological Process: positive regulation of heart rate [UNKNOWN][IEA]
    positive regulation of JUN kinase activity [UNKNOWN][IEA]
    phosphoinositide 3-kinase cascade [UNKNOWN][IEA]
    peptide hormone secretion [UNKNOWN][IEA]
    blood vessel morphogenesis [UNKNOWN][IEA]
    positive regulation of mitosis [UNKNOWN][IEA]
    regulation of pH [UNKNOWN][IEA]
    dorsal/ventral pattern formation [UNKNOWN][IEA]
    skeletal system development [UNKNOWN]
    response to hypoxia [UNKNOWN][IEP]
    in utero embryonic development [UNKNOWN][IEA]
    elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger [UNKNOWN][IEA]
    positive regulation of cardiac muscle hypertrophy [UNKNOWN][IEA]
    calcium-mediated signaling [UNKNOWN][IEA]
    natriuresis [UNKNOWN][IEA]
    diuresis [UNKNOWN][IEA]
    G-protein coupled receptor protein signaling pathway [UNKNOWN]
    neural crest cell development [UNKNOWN][IEA]
    nitric oxide transport [UNKNOWN][IEA]
    cell-cell signaling [UNKNOWN][IEA]
    negative regulation of cAMP biosynthetic process [UNKNOWN][IEA]
    respiratory gaseous exchange [UNKNOWN][IEA]
    regulation of systemic arterial blood pressure by endothelin [UNKNOWN][IEA]
    body fluid secretion [UNKNOWN]
    inositol phosphate-mediated signaling [UNKNOWN][IEA]
    negative regulation of nitric-oxide synthase biosynthetic process [UNKNOWN][IEA]
    prostaglandin biosynthetic process [UNKNOWN][IEA]
    vein smooth muscle contraction [UNKNOWN][IEA]
    artery smooth muscle contraction [UNKNOWN]
    activation of phospholipase D activity by G-protein coupled receptor protein signaling pathway [UNKNOWN][IEA]
    glucose transport [UNKNOWN][IEA]
    membrane depolarization [IMP]
    positive regulation of cell migration [UNKNOWN]
    cartilage development [UNKNOWN][IEA]
    positive regulation of MAP kinase activity [UNKNOWN]
    positive regulation of prostaglandin-endoperoxidase synthase activity [UNKNOWN][IEA]
    positive regulation of cell proliferation [UNKNOWN][TAS]
    middle ear morphogenesis [UNKNOWN][IEA]
    vasoconstriction [UNKNOWN]
    protein kinase C deactivation [UNKNOWN][IEA]
    positive regulation of smooth muscle contraction [UNKNOWN][IDA]
    positive regulation of smooth muscle cell proliferation [UNKNOWN][IEA]
    heart development [UNKNOWN][IEA]
    positive regulation of cell size [UNKNOWN][IEA]
    patterning of blood vessels [UNKNOWN][IEA]
    regulation of vasoconstriction [IEA]
    positive regulation of sarcomere organization [UNKNOWN][IEA]
    positive regulation of hormone secretion [UNKNOWN][IEA]
    cell surface receptor linked signaling pathway [UNKNOWN]
    intracellular protein kinase cascade [IDA]
    rhythmic excitation [UNKNOWN][IEA]
    activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway [UNKNOWN][IEA]
    regulation of blood pressure [UNKNOWN][IMP]
    negative regulation of hormone secretion [IDA]
    elevation of cytosolic calcium ion concentration [UNKNOWN]
    [NOT]neutrophil chemotaxis [UNKNOWN]
    Molecular Function: protein binding [UNKNOWN]
    endothelin A receptor binding [UNKNOWN][IMP]
    endothelin B receptor binding [UNKNOWN][IMP]
    receptor binding [UNKNOWN]
    hormone activity [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYFPVIFSL LFVAFQGAPE TAVLGAELSP RAEKEVQSPP PSTSWRPRRS KRCSCSSLMD  60
   61 KECVYFCHLD IIWVNTPERV VPYGLGSPSR SKRSLKDLLP TKTTDQGNRC QCAHQKDKKC 120
  121 WNFCQADKEL RAQSTMQKGV KDFKKGKPCP KLGKKCIYQQ LVEGRKLRRL EAISNSIKTS 180
  181 FRVAKLKAEL YRDQKLIHNR AH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle