Protein Overview: LEUK_RAT

General Information:
Name(s) found:	LEUK_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|S00842 leukosialin precursor - rat (fragment) [NCBI NR] gi\|747878\|emb\|CAA68281.1\| leukosialin [Rattus norvegicus] [NCBI NR] gi\|126215\|sp\|P13838.1\|LEUK_RAT RecName: Full=Leukosialin; AltName: Full=Leukocyte sialoglycoprotein; AltName: Full=Sialophorin; AltName: Full=W3/13 antigen; AltName: CD_antigen=CD43; Flags: Precursor [NCBI NR] Leukosialin (Fragment) OS=Rattus norvegicus GN=Spn PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):1-180109243 Leukosialin precursor [hmr_yeast5_DM3-1_pombe.fasta] leukosialin [Rattus norvegicus]gi\|92465\|pir\|\|S00842 leukosialin precursor - rat (fragment)gi\|126215\|sp\|P13838\|LEUK_RAT Leukosialin precursor (Leucocyte sialoglycoprotein) (Sialophorin) (CD43) (W3/13 antigen) [nrdb_11152004_Chlamydomonas] Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (W3/13 antigen) (CD43 antigen) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] leukosialin [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Leukosialin (Fragment) OS=Rattus norvegicus GN=Spn [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	378 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [UNKNOWN] basement membrane [UNKNOWN] extracellular space [UNKNOWN] uropod [UNKNOWN] microvillus [IDA] cleavage furrow [IDA] membrane [IDA] external side of plasma membrane [UNKNOWN] integral to membrane [IEA] plasma membrane [UNKNOWN] cell surface [IDA]
Biological Process:	T cell costimulation [UNKNOWN] negative regulation of cell adhesion [UNKNOWN] cell surface receptor linked signaling pathway [UNKNOWN] positive regulation of T cell proliferation [UNKNOWN] induction of apoptosis by extracellular signals [UNKNOWN] defense response to bacterium [UNKNOWN] response to protozoan [UNKNOWN] monocyte activation [IEP] positive regulation of tumor necrosis factor biosynthetic process [UNKNOWN] chronic inflammatory response [IEP] leukocyte aggregation [IMP] negative regulation of T cell proliferation [UNKNOWN] negative regulation of T cell activation [UNKNOWN] negative regulation of type IV hypersensitivity [UNKNOWN] negative thymic T cell selection [UNKNOWN] regulation of defense response to virus [UNKNOWN] regulation of immune response [UNKNOWN]
Molecular Function:	protein domain specific binding [IPI] protein binding [UNKNOWN] bacterial cell surface binding [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WAQVVSQENL PNTMTMLPFT PNSESPSTSE ALSTYSSIAT VPVTEDPKES ISPWGQTTAP  60
   61 ASSIPLGTPE LSSFFFTSAG ASGNTPVPEL TTSQEVSTEA SLVLFPKSSG VASDPPVTIT 120
  121 NPATSSAVAS TSLETFKGTS APPVTVTSST MTSGPFVATT VSSETSGPPV TMATGSLGPS 180
  181 KETHGLSATI ATSSGESSSV AGGTPVFSTK ISTTSTPNPI TTVPPRPGSS GMLLVSMLIA 240
  241 LTVVLVLVAL LLLWRQRQKR RTGALTLSRG GKRNGTVDAW AGPARVPDEE ATTASGSGGN 300
  301 KSSGAPETDG SGQRPTLTTF FSRRKSRQGS VALEELKPGT GPNLKGEEEP LVGSEDEAVE 360
  361 TPTSDGPQAK DGAAPQSL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: LEUK_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: