Protein Overview: CAC1B_RAT

General Information:
Name(s) found:	CAC1B_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|206572\|gb\|AAA42014.1\| calcium channel alpha-1 subunit [NCBI NR] gi\|1705855\|sp\|Q02294.1\|CAC1B_RAT RecName: Full=Voltage-dependent N-type calcium channel subunit alpha-1B; AltName: Full=Voltage-gated calcium channel subunit alpha Cav2.2; AltName: Full=Calcium channel, L type, alpha-1 polypeptide isoform 5; AltName: Full [NCBI NR] (Q02294) Voltage-dependent N-type calcium channel alpha-1B subunit (Voltage-gated calcium channel alpha subunit Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII) [Swiss-Prot] Voltage-dependent N-type calcium channel subunit alpha-1B OS=Rattus norvegicus GN=Cacna1b PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):None Voltage-dependent N-type calcium channel alpha-1B subunit [hmr_yeast5_DM3-1_pombe.fasta] Voltage-dependent N-type calcium channel alpha-1B subunit (Voltage-gated calcium channel alpha subunit Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII)gi\|206572\|gb\|AAA42014.1\| calcium channel alpha-1 sub [nrdb_11152004_Chlamydomonas] Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage-gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] calcium channel alpha-1 subunit [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Isoform 1 of Voltage-dependent N-type calcium channel subunit alpha-1B OS=Rattus norvegicus GN=Cacna1b [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	2336 amino acids
Gene Ontology:
Cellular Component:	dendrite [UNKNOWN] synaptosome [IDA] dendritic shaft [IDA] membrane [IEA] voltage-gated calcium channel complex [UNKNOWN][IEA] integral to membrane [IEA] neuronal cell body [UNKNOWN][IDA] plasma membrane [UNKNOWN][IDA] axon terminus [IDA]
Biological Process:	response to ethanol [IEP] ion transport [IEA] locomotory behavior [UNKNOWN] transmembrane transport [IEA] positive regulation of neurotransmitter secretion [IMP] calcium ion transport [UNKNOWN][IEA][IMP] regulation of heart contraction [UNKNOWN] response to organic cyclic substance [IDA] response to testosterone stimulus [IMP] regulation of blood pressure [UNKNOWN] neurotransmitter secretion [UNKNOWN]
Molecular Function:	nucleotide binding [IEA] ion channel activity [IEA] ATP binding [IEA] protein binding [UNKNOWN][IPI] protein C-terminus binding [UNKNOWN] voltage-gated ion channel activity [IEA] voltage-gated calcium channel activity [UNKNOWN][IEA][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRFGDELGG RYGGTGGGER ARGGGAGGAG GPGQGGLPPG QRVLYKQSIA QRARTMALYN  60
   61 PIPVKQNCFT VNRSLFVFSE DNVVRKYAKR ITEWPPFEYM ILATIIANCI VLALEQHLPD 120
  121 GDKTPMSERL DDTEPYFIGI FCFEAGIKII ALGFVFHKGS YLRNGWNVMD FVVVLTEILA 180
  181 TAGTDFDLRT LRAVRVLRPL KLVSGIPSLQ VVLKSIMKAM VPLLQIGLLL FFAILMFAII 240
  241 GLEFYMGKFH KACFPNSTDA EPVGDFPCGK EAPARLCDSD TECREYWPGP NFGITNFDNI 300
  301 LFAILTVFQC ITMEGWTDIL YNTNDAAGNT WNWLYFIPLI IIGSFFMLNL VLGVLSGEFA 360
  361 KERERVENRR AFLKLRRQQQ IERELNGYLE WIFKAEEVML AEEDKNAEEK SPLDAVLKRA 420
  421 ATKKSRNDLI HAEEGEDRFV DLCAAGSPFA RASLKSGKTE SSSYFRRKEK MFRFLIRRMV 480
  481 KAQSFYWVVL CVVALNTLCV AMVHYNQPQR LTTALYFAEF VFLGLFLTEM SLKMYGLGPR 540
  541 SYFRSSFNCF DFGVIVGSIF EVVWAAIKPG TSFGISVLRA LRLLRIFKVT KYWNSLRNLV 600
  601 VSLLNSMKSI ISLLFLLFLF IVVFALLGMQ LFGGQFNFQD ETPTTNFDTF PAAILTVFQI 660
  661 LTGEDWNAVM YHGIESQGGV SKGMFSSFYF IVLTLFGNYT LLNVFLAIAV DNLANAQELT 720
  721 KDEEEMEEAA NQKLALQKAK EVAEVSPMSA ANISIAARQQ NSAKARSVWE QRASQLRLQN 780
  781 LRASCEALYS EMDPEERLRY ASTRHVRPDM KTHMDRPLVV EPGRDGLRGP AGNKSKPEGT 840
  841 EATEGADPPR RHHRHRDRDK TSASTPAGGE QDRTDCPKAE STETGAREER ARPRRSHSKE 900
  901 APGADTQVRC ERSRRHHRRG SPEEATEREP RRHRAHRHAQ DSSKEGKEGT APVLVPKGER 960
  961 RARHRGPRTG PRETENSEEP TRRHRAKHKV PPTLEPPERE VAEKESNVVE GDKETRNHQP1020
 1021 KEPRCDLEAI AVTGVGSLHM LPSTCLQKVD EQPEDADNQR NVTRMGSQPS DPSTTVHVPV1080
 1081 TLTGPPGEAT VVPSANTDLE GQAEGKKEAE ADDVLRRGPR PIVPYSSMFC LSPTNLLRRF1140
 1141 CHYIVTMRYF EMVILVVIAL SSIALAAEDP VRTDSFRNNA LKYMDYIFTG VFTFEMVIKM1200
 1201 IDLGLLLHPG AYFRDLWNIL DFIVVSGALV AFAFSSFMGG SKGKDINTIK SLRVLRVLRP1260
 1261 LKTIKRLPKL KAVFDCVVNS LKNVLNILIV YMLFMFIFAV IAVQLFKGKF FYCTDESKEL1320
 1321 ERDCRGQYLD YEKEEVEAQP RQWKKYDFHY DNVLWALLTL FTVSTGEGWP MVLKHSVDAT1380
 1381 YEEQGPSPGF RMELSIFYVV YFVVFPFFFV NIFVALIIIT FQEQGDKVMS ECSLEKNERA1440
 1441 CIDFAISAKP LTRYMPQNKQ SFQYKTWTFV VSPPFEYFIM AMIALNTVVL MMKFYDAPYE1500
 1501 YELMLKCLNI VFTSMFSLEC ILKIIAFGVL NYFRDAWNVF DFVTVLGSIT DILVTEIANN1560
 1561 FINLSFLRLF RAARLIKLCR QGYTIRILLW TFVQSFKALP YVCLLIAMLF FIYAIIGMQV1620
 1621 FGNIALDDGT SINRHNNFRT FLQALMLLFR SATGEAWHEI MLSCLGNRAC DPHANASECG1680
 1681 SDFAYFYFVS FIFLCSFLML NLFVAVIMDN FEYLTRDSSI LGPHHLDEFI RVWAEYDPAA1740
 1741 CGRISYNDMF EMLKHMSPPL GLGKKCPARV AYKRLVRMNM PISNEDMTVH FTSTLMALIR1800
 1801 TALEIKLAPA GTKQHQCDAE LRKEISSVWA NLPQKTLDLL VPPHKPDEMT VGKVYAALMI1860
 1861 FDFYKQNKTT RDQTHQAPGG LSQMGPVSLF HPLKATLEQT QPAVLRGARV FLRQKSATSL1920
 1921 SNGGAIQTQE SGIKESLSWG TQRTQDVLYE ARAPLERGHS AEIPVGQPGA LAVDVQMQNM1980
 1981 TLRGPDGEPQ PGLESQGRAA SMPRLAAETQ PAPNASPMKR SISTLAPRPH GTQLCNTVLD2040
 2041 RPPPSQVSHH HHHRCHRRRD KKQRSLEKGP SLSVDTEGAP STAAGSGLPH GEGSTGCRRE2100
 2101 RKQERGRSQE RRQPSSSSSE KQRFYSCDRF GSREPPQPKP SLSSHPISPT AALEPGPHPQ2160
 2161 GSGSVNGSPL MSTSGASTPG RGGRRQLPQT PLTPRPSITY KTANSSPVHF AEGQSGLPAF2220
 2221 SPGRLSRGLS EHNALLQKEP LSQPLASGSR IGSDPYLGQR LDSEASAHNL PEDTLTFEEA2280
 2281 VATNSGRSSR TSYVSSLTSQ SHPLRRVPNG YHCTLGLSTG VRARHSYHHP DQDHWC

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: CAC1B_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: