General Information: |
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Name(s) found: |
PAI1_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 402 amino acids |
Gene Ontology: |
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Cellular Component: |
extracellular space
[UNKNOWN][IDA]
soluble fraction [IDA] extracellular matrix [UNKNOWN] extracellular region [UNKNOWN][IEA] plasma membrane [UNKNOWN] |
Biological Process: |
response to cytokine stimulus
[IEP]
positive regulation of blood coagulation [UNKNOWN] regulation of angiogenesis [UNKNOWN][IEA] negative regulation of proteolysis [TAS] positive regulation of angiogenesis [UNKNOWN] chronological cell aging [UNKNOWN][IEA] wound healing [IMP] negative regulation of plasminogen activation [UNKNOWN] response to glucocorticoid stimulus [IEP] negative regulation of endopeptidase activity [IC][UNKNOWN] negative regulation of smooth muscle cell migration [UNKNOWN] positive regulation of receptor-mediated endocytosis [UNKNOWN][IMP] cellular response to chemical stimulus [UNKNOWN] defense response to Gram-negative bacterium [UNKNOWN] negative regulation of fibrinolysis [UNKNOWN] positive regulation of monocyte chemotaxis [UNKNOWN] positive regulation of inflammatory response [UNKNOWN] negative regulation of vascular wound healing [UNKNOWN] response to reactive oxygen species [IEP] tissue regeneration [IEP] regulation of cell proliferation [UNKNOWN][IEA] negative regulation of cell adhesion mediated by integrin [UNKNOWN] positive regulation of interleukin-8 production [UNKNOWN] cellular response to lipopolysaccharide [UNKNOWN] negative regulation of apoptosis [UNKNOWN] glucose homeostasis [IEP] regulation of receptor activity [UNKNOWN] negative regulation of cell migration [UNKNOWN] positive regulation of coagulation [IMP] |
Molecular Function: |
peptidase inhibitor activity
[IEA]
serine-type endopeptidase inhibitor activity [UNKNOWN][TAS] protein binding [UNKNOWN][IEA] serine-type endopeptidase activity [IEA] protease binding [UNKNOWN][IEA] receptor binding [UNKNOWN] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MQMSSALTCL TLGLVLVFGK GFASPLPESH TAQQATNFGV KVFQHVVQAS KDRNVVFSPY 60 61 GVSSVLAMLQ LTTAGKTRQQ IQDAMGFNIS ERGTAPALRK LSKELMGSWN KNEISTADAI 120 121 FVQRDLELVQ GFMPHFFKLF RTTVKQVDFS EVERARFIIN DWVERHTKGM ISDLLAKGAV 180 181 NELTRLVLVN ALYFNGQWKT PFLEASTHQR LFHKSDGSTI SVPMMAQNNK FNYTEFTTPD 240 241 GHEYDILELP YHGETLSMFI AAPFEKDVPL SAITNILDAE LIRQWKSNMT RLPRLLILPK 300 301 FSLETEVDLR GPLEKLGMTD IFSSTQADFT SLSDQEQLSV AQALQKVKIE VNESGTVASS 360 361 STAILVSARM APTEMVLDRS FLFVVRHNPT ETILFMGQLM EP |
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