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Protein Overview: PHLA3_RAT

General Information:
Name(s) found: PHLA3_RAT [Swiss-Prot]
Description(s) found:
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  • gi|81883273|sp|Q5PQT7.1|PHLA3_RAT RecName: Full=Pleckstrin homology-like domain family A member 3; AltName: Full=TDAG51/Ipl homolog 1 [NCBI NR]
  • gi|62659369|ref|XP_573458.1| PREDICTED: pleckstrin homology-like domain, family A, member 3 (predicted) [Rattus norvegicus] [NCBI NR]
  • gi|58865988|ref|NP_001012206.1| pleckstrin homology-like domain, family A, member 3 [Rattus norvegicus] [NCBI NR]
  • gi|56269344|gb|AAH87038.1| Pleckstrin homology-like domain, family A, member 3 [Rattus norvegicus] [NCBI NR]
  • ref|XP_344144.1| similar to TDAG51/Ipl homologue 1 [Rattus norvegicus] [NCBI NR]
  • gi|149058527|gb|EDM09684.1| rCG46130 [Rattus norvegicus] [NCBI NR]
  • Pleckstrin homology-like domain family A member 3 OS=Rattus norvegicus GN=Phlda3 PE=2 SV=1 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):13-42882705 [hmr_yeast5_DM3-1_pombe.fasta]
  • similar to TDAG51/Ipl homologue 1 [HMR_022704-rand.fasta]
  • similar to TDAG51/Ipl homologue 1 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Pleckstrin homology-like domain family A member 3 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • Tax_Id=10116 Pleckstrin homology-like domain, family A, member 3 [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta]
  • Pleckstrin homology-like domain family A member 3 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • rCG46130 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • pleckstrin homology-like domain, family A, member 3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Pleckstrin homology-like domain, family A, member 3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 SIMILAR TO TDAG51/IPL HOMOLOGUE 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Phlda3 Pleckstrin homology-like domain family A member 3 [rat-ipi-250309-contam.fasta]
  • pleckstrin homology-like domain family A member 3 [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Pleckstrin homology-like domain family A member 3 OS=Rattus norvegicus GN=Phlda3 [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 125 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    plasma membrane [UNKNOWN][ISS]
    Biological Process: induction of apoptosis [UNKNOWN][ISS]
    apoptosis [IEA]
    DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis [UNKNOWN][ISS]
    negative regulation of protein kinase B signaling cascade [UNKNOWN][ISS]
    Molecular Function: phosphatidylinositol-3,4,5-trisphosphate binding [UNKNOWN][ISS]
    phosphatidylinositol-4,5-bisphosphate binding [UNKNOWN][ISS]
    identical protein binding [UNKNOWN][IEA]
    protein binding [UNKNOWN]
    phosphatidylinositol-5-phosphate binding [UNKNOWN][ISS]
    phosphatidylinositol-3,5-bisphosphate binding [UNKNOWN][ISS]
    phosphatidylinositol-3-phosphate binding [UNKNOWN][ISS]
    phosphatidylinositol-3,4-bisphosphate binding [UNKNOWN][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAAATVLKE GVLEKRSGGL LQLWKRKRCV LTERGLQLFE AKGTGGRPKE LSFSRIKAVE  60
   61 CVESTGRHIY FTLVTEGGGE IDFRCPLEDP GWNAQITLGL VKFKNQQAIQ TVRARQSLGT 120
  121 GTLVS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle