Protein Overview: SCAP_RAT

General Information:
Name(s) found:	SCAP_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|62654357\|ref\|XP_217279.3\| PREDICTED: similar to SREBP cleavage activating protein [Rattus norvegicus] [NCBI NR] gi\|166200289\|sp\|A2RRU4.1\|SCAP_RAT RecName: Full=Sterol regulatory element-binding protein cleavage-activating protein; Short=SREBP cleavage-activating protein; Short=SCAP [NCBI NR] gi\|155369287\|ref\|NP_001094436.1\| SREBF chaperone [Rattus norvegicus] [NCBI NR] gi\|124297163\|gb\|AAI31853.1\| Scap protein [Rattus norvegicus] [NCBI NR] gi\|109485406\|ref\|XP_001077128.1\| PREDICTED: similar to SREBP cleavage activating protein [Rattus norvegicus] [NCBI NR] Sterol regulatory element-binding protein cleavage-activating protein OS=Rattus norvegicus GN=Scap PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):8-118749904 [hmr_yeast5_DM3-1_pombe.fasta] Tax_Id=10116 PREDICTED: similar to SREBP cleavage activating protein [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Scap protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] SREBF chaperone [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] PREDICTED: similar to SREBP cleavage activating protein [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Scap Sterol regulatory element-binding protein cleavage-activating protein [rat-ipi-250309-contam.fasta] Sterol regulatory element-binding protein cleavage-activating protein OS=Rattus norvegicus GN=Scap [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1276 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [UNKNOWN][IEA] ER to Golgi transport vesicle membrane [IEA] membrane [IEA] microsome [IDA] integral to membrane [IEA] cytoplasmic vesicle [IEA] Golgi membrane [IEA] endoplasmic reticulum [IEA] Golgi apparatus [IEA] protein complex [IDA]
Biological Process:	response to hypoxia [UNKNOWN][IEA] response to insulin stimulus [UNKNOWN][IEA] regulation of cholesterol biosynthetic process [UNKNOWN][IEA] cholesterol metabolic process [UNKNOWN][IEA] steroid metabolic process [IEA] aging [IEP] positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway [UNKNOWN][IEA] regulation of fatty acid metabolic process [UNKNOWN] regulation of fatty acid biosynthetic process [UNKNOWN][IEA]
Molecular Function:	protein binding [UNKNOWN] protein complex binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLTERLREK ISQAFYNHGL LCASYPIPII LFTGLCILAC CYPLLKLPLP GTGPVEFSTP  60
   61 VKGYSPPPAD SDHKQGEPSE QPEWYVGAPV AYIQQIFVKS SVSPWHRNLL AVDVFRSPLS 120
  121 RAFQLVEEIR NHVLRDSSGT KSLEEVCLQV TDLLPGLRKL RSLLPEHGCL LLSPGNFWQN 180
  181 DWERFHADPD IIGTIHQHEP KTLQTSATLK DLLFGVPGKY SGVSLYTRKR MVSYTITLVF 240
  241 QRYHAKFLSS LRARLMLLHP SPNCSLRAEN LVHVHFKEEI GIAELIPLVT TYIILFAYIY 300
  301 FSTRKIDMVK SKWGLALAAV VTVLSSLLMS VGLCTLFGLT PTLNGGEIFP YLVVVIGLEN 360
  361 VLVLTKSVVS TPVDLEVKLR IAQGLSSESW SIMKNVATEL GIILIGYFTL VPAIQEFCLF 420
  421 AVVGLVSDFF LQMLFFTTVL SIDIRRMELA DLNKRLPPES CLPSAKPVGR PARYERQLAV 480
  481 RPSTPHTITL QPSSFRNLRL PKRLRVIYFL ARTRLAQRLI MAGTVVWIGI LVYTDPAGLR 540
  541 TYLAAQVTEQ SPLGEGSLGP MPVPSGVLPA SHPDPAFSIF PPDAPKLPEN QTLPGELPEH 600
  601 AVPAEGVQDS RAPEVTWGPE DEELWRKLSF RHWPTLFNYY NITLAKRYIS LLPVIPVTLH 660
  661 LNPREALEGR HPQDGRTAWA PPEPLPAGLW ETGPKGPGGT QTHGDITLYK VAALGLAAGI 720
  721 VLVLLLLCLY RVLCPRNYGQ PGGGAGRRRR GELPCDDYGY APPETEIVPL VLRGHLMDIE 780
  781 CLASDGMLLV SCCLAGQVCV WDAQTGDCLT RIPRPGPRRD SCGGGAFEAQ ENWERLSDGG 840
  841 KASPEEPGDS PPLRRRPRGP PPPSLFGDQP DLTCLIDTNF SVQLPPEPTQ PEPRHRAGCG 900
  901 RSRDSGYDFS RLVQRVYQEE GLAAVHMSAL RPPSPGPPLP QASQEEGTAP EKGSPPLAWA 960
  961 PSTAGSIWSL ELQGSLIVVG RSSGRLEVWD AIEGVLCCSN EEISSGITAL VFLDRRIVAA1020
 1021 RLNGSLDFFS LETHTSLSPL QFRGTPGRGS SPSSPVYSSS NTVACHLTHT VPCAHQKPIT1080
 1081 ALRAAAGRLV TGSQDHTLRV FRLEDSCCLF TLQGHSGAIT TVYIDQTMVL ASGGQDGAIC1140
 1141 LWDVLTGSRV SHTFAHRGDV TSLTCTTSCV ISSGLDDFIN IWDRSTGIKL YSIQQDLGCG1200
 1201 ASLGVISDNL LVTGGQGCVS FWDLNYGDLL QTVYLGKNSE AQPARQILVL DNAAIVCNFG1260
 1261 SELSLVYVPS VLEKLD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: SCAP_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: