Protein Overview: AL1A3_RAT

General Information:
Name(s) found:	AL1A3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|52782764\|sp\|Q8K4D8.1\|AL1A3_RAT RecName: Full=Aldehyde dehydrogenase family 1 member A3; AltName: Full=Aldehyde dehydrogenase 6; AltName: Full=Retinaldehyde dehydrogenase 3; Short=RALDH-3 [NCBI NR] gi\|23463283\|ref\|NP_695212.1\| aldehyde dehydrogenase 1A3 [Rattus norvegicus] [NCBI NR] gi\|22652437\|gb\|AAN03711.1\|AF434845_1 aldehyde dehydrogenase 6 [Rattus norvegicus] [NCBI NR] (Q8K4D8) Aldehyde dehydrogenase 1A3 (EC 1.2.1.5) (Aldehyde dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3) [Swiss-Prot] Aldehyde dehydrogenase family 1 member A3 OS=Rattus norvegicus GN=Aldh1a3 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):1-117959434 Aldehyde dehydrogenase 6 [hmr_yeast5_DM3-1_pombe.fasta] aldehyde dehydrogenase family 1, subfamily A3; aldehyde dehydrogenase 6 [HMR_022704-rand.fasta] Aldehyde dehydrogenase 1A3 (Aldehyde dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3)gi\|23463283\|ref\|NP_695212.1\| aldehyde dehydrogenase family 1, subfamily A3 [Rattus norvegicus]gi\|22652437\|gb\|AAN03711.1\| aldehyde dehydrogenase 6 [Rattus norv [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Aldehyde dehydrogenase 1A3 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Aldehyde dehydrogenase family 1 member A3 (Aldehyde dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] aldehyde dehydrogenase family 1, subfamily A3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] aldehyde dehydrogenase 6 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 ALDEHYDE DEHYDROGENASE 1A3 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] aldehyde dehydrogenase 1A3 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Aldehyde dehydrogenase 1A3 (Aldehyde dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Aldh1a3 Aldehyde dehydrogenase family 1 member A3 [rat-ipi-250309-contam.fasta] Aldehyde dehydrogenase family 1 member A3 OS=Rattus norvegicus GN=Aldh1a3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	512 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [UNKNOWN][IEA] cytosol [NAS]
Biological Process:	olfactory pit development [UNKNOWN][IEA] nucleus accumbens development [UNKNOWN][IEA] embryonic camera-type eye development [UNKNOWN][IEA] optic cup morphogenesis involved in camera-type eye development [UNKNOWN][IEA] retinoic acid metabolic process [UNKNOWN] retinal metabolic process [UNKNOWN][IEA] face development [UNKNOWN][IEA] pituitary gland development [IEP] retinoic acid biosynthetic process [UNKNOWN][IEA] kidney development [IEP] embryonic eye morphogenesis [UNKNOWN][IEA] response to drug [IEP] positive regulation of apoptosis [UNKNOWN][IEA] oxidation reduction [IEA]
Molecular Function:	aldehyde dehydrogenase (NAD) activity [UNKNOWN][IEA] protein homodimerization activity [UNKNOWN][IEA] oxidoreductase activity [IEA] aldehyde dehydrogenase [NAD(P)+] activity [UNKNOWN][IDA] thyroid hormone binding [UNKNOWN][IEA] NAD binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATANGAVEN GQPDGKPPAL PRPIRNLEVK FTKIFINNDW HEPKSGRKFA TYNPSTLEKI  60
   61 CEVEEGDKPD VDKAVEAAQA AFQRGSPWRR LDALSRGQLL HQLADLIERD RAILATLETM 120
  121 DTGKPFLHAF FVDLEGCIKT FRYFAGWADK IQGRTIPTDD NVMCFTRHEP IGVCGAITPW 180
  181 NFPLLMLAWK LAPALCCGNT VVLKPAEQTP LTALYLASLI KEVGFPPGVV NIVPGFGPTV 240
  241 GAAISSHPQI NKIAFTGSTE VGKLVKEAAS RSNLKRVTLE LGGRNPCIVC ADADLDLAVE 300
  301 CAHQGVFFNQ GQCCTAASRV FVEEQVYGEF VRRSVEFAKK RPVGDPFDAK TEQGPQIDQK 360
  361 QFDKILELIE SGKKEGAKLE CGGSAMEDRG LFIKPTVFSD VTDNMRIAKE EIFGPVQPIL 420
  421 KFKNLEEVIK RANSTDYGLT AAVFTKNLDK ALKLASALES GTVWVNCYNA FYAQAPFGGF 480
  481 KMSGNGRELG EYALAEYTEV KTVTIKLDEK NP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: AL1A3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: