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Protein Overview: FOXM1_RAT

General Information:
Name(s) found: FOXM1_RAT [Swiss-Prot]
Description(s) found:
Found 7 descriptions.
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  • Forkhead box protein M1 OS=Rattus norvegicus GN=Foxm1 PE=2 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 759 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IEA]
    cellular_component [ND]
    Biological Process: regulation of oxygen and reactive oxygen species metabolic process [UNKNOWN]
    positive regulation of cell proliferation [UNKNOWN]
    regulation of Ras protein signal transduction [UNKNOWN]
    regulation of transcription, DNA-dependent [IEA]
    transcription from RNA polymerase II promoter [UNKNOWN]
    response to cAMP [IEP]
    vasculogenesis [UNKNOWN]
    positive regulation of transcription from RNA polymerase II promoter [UNKNOWN]
    regulation of cell proliferation [UNKNOWN]
    regulation of cell cycle arrest [UNKNOWN]
    liver development [UNKNOWN]
    senescence [UNKNOWN]
    negative regulation of stress-activated MAPK cascade [UNKNOWN]
    response to gonadotropin stimulus [IEP]
    positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN]
    Molecular Function: DNA binding [UNKNOWN][IDA]
    transcription factor activity [UNKNOWN][IEA][ISS]
    protein binding [UNKNOWN]
    RNA polymerase II transcription factor activity [UNKNOWN]
    sequence-specific DNA binding [IDA][IEA]
    promoter binding [UNKNOWN]
    transcription activator activity [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRTSPRRPLI LKRRRLPLPI QNAPSETSEE EAKRSPGQQE PTQAQASQDV AESSSCKFPA  60
   61 GIKIINHPTV PNTQVVAIPN NADIQSIITA LTAKGKESGS SGPNKFILIS SGGASSHPPD 120
  121 PQSQAQTSTD SKRTELITET LGPKPGAKGV PVPKPPGALP RQRQESCGGE AAGCTLDNSL 180
  181 TNIQWLGKMS SDGLGRCSIK QELEEKENCH LEQNRVKVEA PSRASVSWQD SVSERPPYSY 240
  241 MAMIQFAINS TERKRMTLKD IYTWIEDHFP YFKHIAKPGW KNSIRHNLSL HDMFVRETSA 300
  301 NGKVSFWTIH PSANRYLTLD QVFKPLEPGS PQSPEHLESQ QKRPNPELRR NVTIKTELPL 360
  361 GARRKMKPLL PRVSSYLVPI QFPVNQSLVL QPSVKVPLPL AASLMSSELA RHSKRVRIAP 420
  421 KVLLSNEGIA PLPATEPMKE EKPLLGEGLL PLLPIQSIKE EVIQPGEDIP HLERPIKVES 480
  481 PPLEEWPSPC ASVKEELSNS WEDSSCSPTP KPKKSYCGLK SPTRCVSEML VTKRREKREV 540
  541 SRSRRKQHLQ PPCLDEPELF FSEDSSTFRP AMEILAESSE PAPQLSCPQE EGGPFKTPIK 600
  601 ETLPVSSTPS KSVLSRDPES WRLTPPAKVG GLDFSPVRTP QGAFGPLPDS LGLMELNTTP 660
  661 LKSVPLFDSP RELLNSEAFD LASDPFSSSP PPHLEAKPGS PELQVPSLSA NRSLTEGLVL 720
  721 DTMNDSLSKI LLDISFPGLE EDPLGPDNIN WSQFIPELR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle