Protein Overview: MFN2_RAT

General Information:
Name(s) found:	MFN2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|47605759\|sp\|Q8R500.1\|MFN2_RAT RecName: Full=Mitofusin-2; AltName: Full=Transmembrane GTPase MFN2; AltName: Full=Mitochondrial transmembrane GTPase FZO1A; Short=Protein HSG [NCBI NR] gi\|20269300\|dbj\|BAB90982.1\| mitochondrial transmembrane GTPase FZO1A [Rattus norvegicus] [NCBI NR] Mitofusin-2 OS=Rattus norvegicus GN=Mfn2 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):5-185788350;5-185788350 Mitochondrial transmembrane GTPase FZO1A [hmr_yeast5_DM3-1_pombe.fasta] Transmembrane GTPase MFN2 (Mitofusin 2) (Mitochondrial transmembrane GTPase FZO1A) (HSG protein)gi\|20269300\|dbj\|BAB90982.1\| mitochondrial transmembrane GTPase FZO1A [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Transmembrane GTPase MFN2 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Mitofusin-2 (Transmembrane GTPase MFN2) (Mitochondrial transmembrane GTPase FZO1A) (Protein HSG) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] mitochondrial transmembrane GTPase FZO1A [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 TRANSMEMBRANE GTPASE MFN2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Transmembrane GTPase MFN2 (Mitofusin-2) (Mitochondrial transmembrane GTPase FZO1A) (Protein HSG) [nr-271106-contam.fasta]
Organism:	Rattus norvegicus
Length:	757 amino acids
Gene Ontology:
Cellular Component:	microtubule cytoskeleton [UNKNOWN] intrinsic to mitochondrial outer membrane [IDA] mitochondrion [UNKNOWN][IDA] membrane [IEA] integral to membrane [IEA] cytosol [IDA] mitochondrial outer membrane [IDA]
Biological Process:	protein targeting to mitochondrion [UNKNOWN][ISS] cell cycle arrest [IDA] camera-type eye morphogenesis [UNKNOWN] negative regulation of Ras protein signal transduction [UNKNOWN] negative regulation of cell proliferation [IMP] mitochondrial fusion [UNKNOWN][IMP] negative regulation of smooth muscle cell proliferation [IDA] blastocyst formation [UNKNOWN] mitochondrion localization [UNKNOWN] mitochondrial membrane organization [UNKNOWN][ISS]
Molecular Function:	nucleotide binding [IEA] GTP binding [IEA][IMP] protein binding [UNKNOWN] GTPase activity [IEA][IMP] GTPase binding [IPI] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLLFSRCNS IVTVKKDKRH MAEVNASPLK HFVTAKKKIN GIFEQLGAYI QESAGFLEDT  60
   61 HRNTELDPVT TEEQVLDVKG YLSKVRGISE VLARRHMKVA FFGRTSNGKS TVINAMLWDK 120
  121 VLPSGIGHTT NCFLRVGGTD GHEAFLLTEG SEEKKSVKTV NQLAHALHQD EQLHAGSLVS 180
  181 VMWPNSKCPL LKDGLVLMDS PGIDVTTELD SWIDKFCLDA DVFVLVANSE STLMQTEKQF 240
  241 FHKVSERLSR PNIFILNNRW DASASEPEYM EEVRRQHMER CTSFLVDELG VVDRAQAGDR 300
  301 IFFVSAKEVL SARVQKAQGM PEGGGALAEG FQVRMFEFQN FERRFEECIS QSAVKTKFEQ 360
  361 HTVRAKQIAE AVRLIMDSLH IAAQEQRVYC LEMREERQDR LRFIDKQLEL LAQDYKLRIK 420
  421 QMTEEVERQV STAMAEEIRR LSVLVDEYQM DFHPSPVVLK VYKNELHRHI EEGLGRNMSD 480
  481 RCSTAIASSL QTMQQDMIDG LKPLLPVSVR NQIDMLVPRQ CFSLSYDLNC DKLCADFQED 540
  541 IEFHFSLGWT MLVNRFLGPK NSRRALLGYN DQVQRPLPLT PANPSMPPLP QGSLTQEELM 600
  601 VSMVTGLASL TSRTSMGILV VGGVVWKAVG WRLIALSFGL YGLLYVYERL TWTTRAKERA 660
  661 FKRQFVEYAS EKLQLIISYT GSNCSHQVQQ ELSGTFAHLC QQVDITRDNL EQEIAAMNKK 720
  721 VEALDSLQSK AKLLRNKAGW LDSELNMFIH QYLQPSR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.34

Protein Overview: MFN2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: