Protein Overview: HNF6_RAT

General Information:
Name(s) found:	HNF6_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|1550795\|emb\|CAA65389.1\| hepatocyte nuclear factor 6 alpha [Rattus norvegicus] [NCBI NR] gi\|13626998\|sp\|P70512.1\|HNF6_RAT RecName: Full=Hepatocyte nuclear factor 6; Short=HNF-6; AltName: Full=One cut domain family member 1 [NCBI NR] gi\|12083605\|ref\|NP_073162.1\| one cut homeobox 1 [Rattus norvegicus] [NCBI NR] Hepatocyte nuclear factor 6 OS=Rattus norvegicus GN=Onecut1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):8-77959107 Splice isoform Alpha of P70512 [hmr_yeast5_DM3-1_pombe.fasta] one cut domain, family member 1; Hepatocyte nuclear factor 6 [HMR_022704-rand.fasta] one cut domain, family member 1 [Rattus norvegicus]gi\|1550795\|emb\|CAA65389.1\| hepatocyte nuclear factor 6 alpha [Rattus norvegicus]gi\|13626998\|sp\|P70512\|HNF6_RAT Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform Alpha of Hepatocyte nuclear factor 6 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_022671) hepatocyte nuclear factor 6 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] one cut domain, family member 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] hepatocyte nuclear factor 6 alpha [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF HEPATOCYTE NUCLEAR FACTOR 6 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] one cut homeobox 1 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Onecut1 Isoform Alpha of Hepatocyte nuclear factor 6 [rat-ipi-250309-contam.fasta] Isoform Alpha of Hepatocyte nuclear factor 6 OS=Rattus norvegicus GN=Onecut1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	465 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IPI]
Biological Process:	B cell differentiation [UNKNOWN] endoderm development [UNKNOWN] regulation of transcription, DNA-dependent [IEA] spleen development [UNKNOWN] epithelial cell development [UNKNOWN] anatomical structure morphogenesis [UNKNOWN] glucose metabolic process [UNKNOWN][IMP] positive regulation of transcription from RNA polymerase II promoter [IMP] regulation of transcription from RNA polymerase II promoter [UNKNOWN] regulation of cell-matrix adhesion [UNKNOWN] liver development [UNKNOWN] cilium assembly [UNKNOWN] cell fate commitment [UNKNOWN] cell differentiation [UNKNOWN] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN] endocrine pancreas development [UNKNOWN] negative regulation of transforming growth factor beta receptor signaling pathway [UNKNOWN] positive regulation of cell migration [UNKNOWN] pancreas development [UNKNOWN]
Molecular Function:	DNA binding [UNKNOWN][IMP] transcription factor activity [UNKNOWN][IEA] sequence-specific DNA binding [IEA] transcription activator activity [UNKNOWN][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNAQLTMEAI GELHGVSHEP VPAPADLLGG SPHARSSVGH RGSHLPPAHP RSMGMASLLD  60
   61 GGSGGSDYHH HHRAPEHSLA GPLHPTMTMA CETPPGMSMP TTYTTLTPLQ PLPPISTVSD 120
  121 KFPHHHHHHH HHHHPHHHQR LAGNVSGSFT LMRDERGLAS MNNLYTPYHK DVAGMGQSLS 180
  181 PLSGSGLGSI HNSQQGLPHY AHPGAAMPTD KMLTPNDFEA HHPAMLGRHG EQHLTPTSAG 240
  241 MVPINGLPPH HPHAHLNAQG HGQLLGTARE PNPSVTGAQV SNGSNSGQME EINTKEVAQR 300
  301 ITTELKRYSI PQAIFAQRVL CRSQGTLSDL LRNPKPWSKL KSGRETFRRM WKWLQEPEFQ 360
  361 RMSALRLAAC KRKEQEHGKD RGNTPKKPRL VFTDVQRRTL HAIFKENKRP SKELQITISQ 420
  421 QLGLELSTVS NFFMNARRRS LDKWQDEGSS NSGNSSSSSS TCTKA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: HNF6_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: