Protein Overview: DYR1A_RAT

General Information:
Name(s) found:	DYR1A_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6978787\|ref\|NP_036923.1\| dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [Rattus norvegicus] [NCBI NR] gi\|6015043\|sp\|Q63470.2\|DYR1A_RAT RecName: Full=Dual specificity tyrosine-phosphorylation-regulated kinase 1A; AltName: Full=Protein kinase minibrain homolog; Short=MNBH; AltName: Full=RP86; AltName: Full=Dual specificity YAK1-related kinase [NCBI NR] gi\|2582816\|emb\|CAA56164.1\| Dual Specificity Yak1-related Kinase (Dyrk) [Rattus norvegicus] [NCBI NR] gi\|149017702\|gb\|EDL76703.1\| dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, isoform CRA_b [Rattus norvegicus] [NCBI NR] (Q63470) Dual-specificity tyrosine-phosphorylation regulated kinase 1A (EC 2.7.1.-) (Protein kinase minibrain homolog) (MNBH) (RP86) (Dual specificity YAK1-related kinase) [Swiss-Prot] Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Rattus norvegicus GN=Dyrk1a PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):11-57666362 Splice isoform Long of Q63470 [hmr_yeast5_DM3-1_pombe.fasta] dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; Dual Specificity Yak1-related kinase [HMR_022704-rand.fasta] dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [Rattus norvegicus]gi\|2582816\|emb\|CAA56164.1\| Dual Specificity Yak1-related Kinase (Dyrk) [Rattus norvegicus]gi\|6015043\|sp\|Q63470\|DYRA_RAT Dual-specificity tyrosine-phosphorylation regula [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform Long of Dual specificity tyrosine-phosphorylation-regulated kinase 1A [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Splice Isoform Long of Dual specificity tyrosine-phosphorylation regulated kinase 1A [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_012791) Dual Specificity Yak1-related kinase; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Splice Isoform Long of Dual-specificity tyrosine-phosphorylation regulated kinase 1A [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] Tax_Id=10116 Ensembl_locations(Chr-bp):11-57666362 Splice isoform Long of Q63470 [EBI-IPI_Drosophila_na_12-13-2007_con_reversed.fasta] Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Protein kinase minibrain homolog) (MNBH) (RP86) (Dual specificity YAK1-related kinase) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Dual Specificity Yak1-related Kinase (Dyrk) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF DUAL-SPECIFICITY TYROSINE-PHOSPHORYLATION REGULATED KINASE 1A [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Dyrk1a Isoform Long of Dual specificity tyrosine-phosphorylation-regulated kinase 1A [rat-ipi-250309-contam.fasta] Isoform Long of Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Rattus norvegicus GN=Dyrk1a [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	763 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] nuclear speck [IDA] nucleolus [IDA]
Biological Process:	peptidyl-tyrosine phosphorylation [UNKNOWN][IDA] nervous system development [TAS] protein amino acid autophosphorylation [IDA] regulation of endocytosis [TAS] protein amino acid phosphorylation [IDA]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] protein tyrosine kinase activity [IDA] protein binding [UNKNOWN] non-membrane spanning protein tyrosine kinase activity [UNKNOWN][IEA] protein serine/threonine kinase activity [IDA] transferase activity [IEA] protein self-association [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHTGGETSAC KPSSVRLAPS FSFHAAGLQM AAQMPHSHQY SDRRQPNISD QQVSALSYSD  60
   61 QIQQPLTNQV MPDIVMLQRR MPQTFRDPAT APLRKLSVDL IKTYKHINEV YYAKKKRRHQ 120
  121 QGQGDDSSHK KERKVYNDGY DDDNYDYIVK NGEKWMDRYE IDSLIGKGSF GQVVKAYDRV 180
  181 EQEWVAIKII KNKKAFLNQA QIEVRLLELM NKHDTEMKYY IVHLKRHFMF RNHLCLVFEM 240
  241 LSYNLYDLLR NTNFRGVSLN LTRKFAQQMC TALLFLATPE LSIIHCDLKP ENILLCNPKR 300
  301 SAIKIVDFGS SCQLGQRIYQ YIQSRFYRSP EVLLGMPYDL AIDMWSLGCI LVEMHTGEPL 360
  361 FSGANEVDQM NKIVEVLGIP PAHILDQAPK ARKFFEKLPD GTWSLKKTKD GKREYKPPGT 420
  421 RKLHNILGVE TGGPGGRRAG ESGHTVADYL KFKDLILRML DYDPKTRIQP YYALQHSFFK 480
  481 KTADEGTNTS NSVSTSPAME QSQSSGTTSS TSSSSGGSSG TSNSGRARSD PTHQHRHSGG 540
  541 HFAAAVQAMD CETHSPQVRQ QFPAPLGWSG TEAPTQVTVE THPVQETTFH VAPQQNALHH 600
  601 HHGNSSHHHH HHHHHHHHHG QQALGNRTRP RVYNSPTNSS STQDSMEVGH SHHSMTSLSS 660
  661 STTSSSTSSS STGNQGNQAY QNRPVAANTL DFGQNGAMDV NLTVYSNPRQ ETGIAGHPTY 720
  721 QFSANTGPAH YMTEGHLTMR QGADREESPM TGVCVQQSPV ASS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.82

Protein Overview: DYR1A_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: