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Protein Overview: GNAS2_RAT

General Information:
Name(s) found: GNAS2_RAT [Swiss-Prot]
Description(s) found:
Found 32 descriptions.
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  • Guanine nucleotide-binding protein G(s) subunit alpha isoforms short OS=Rattus norvegicus GN=Gnas PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 394 amino acids

    Gene Ontology:
    Cellular Component: synaptic vesicle [IEA]
    synapse [IEA]
    extracellular region [IEA]
    intracellular part [IDA]
    plasma membrane [UNKNOWN][IDA]
    membrane fraction [UNKNOWN][IDA]
    endosome [IDA]
    heterotrimeric G-protein complex [IDA]
    cytoplasm [UNKNOWN][IDA]
    sarcolemma [IDA]
    ruffle [IEA]
    cell junction [IEA]
    cytoplasmic vesicle [IEA]
    vesicle [IDA]
    intrinsic to membrane [UNKNOWN]
    trans-Golgi network membrane [UNKNOWN]
    Biological Process: activation of adenylate cyclase activity by dopamine receptor signaling pathway [UNKNOWN]
    G-protein coupled receptor protein signaling pathway [IEA][IMP]
    signal transduction [IEA]
    post-embryonic body morphogenesis [UNKNOWN]
    post-embryonic development [UNKNOWN]
    energy reserve metabolic process [UNKNOWN]
    embryonic cranial skeleton morphogenesis [UNKNOWN]
    activation of adenylate cyclase activity by G-protein signaling pathway [UNKNOWN][IDA]
    positive regulation of osteoblast differentiation [UNKNOWN]
    hormone-mediated signaling pathway [UNKNOWN]
    skeletal system development [UNKNOWN]
    positive regulation of osteoclast differentiation [UNKNOWN]
    response to drug [UNKNOWN]
    endochondral ossification [UNKNOWN]
    embryonic hindlimb morphogenesis [UNKNOWN]
    cartilage development [UNKNOWN]
    Molecular Function: nucleotide binding [IEA]
    GTP binding [IEA][TAS]
    identical protein binding [UNKNOWN]
    protein binding [UNKNOWN]
    guanyl nucleotide binding [IEA]
    signal transducer activity [IDA][IEA]
    mu-type opioid receptor binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGCLGNSKTE DQRNEEKAQR EANKKIEKQL QKDKQVYRAT HRLLLLGAGE SGKSTIVKQM  60
   61 RILHVNGFNG EGGEEDPQAA RSNSDGEKAT KVQDIKNNLK EAIETIVAAM SNLVPPVELA 120
  121 NPENQFRVDY ILSVMNVPNF DFPPEFYEHA KALWEDEGVR ACYERSNEYQ LIDCAQYFLD 180
  181 KIDVIKQADY VPSDQDLLRC RVLTSGIFET KFQVDKVNFH MFDVGGQRDE RRKWIQCFND 240
  241 VTAIIFVVAS SSYNMVIRED NQTNRLQEAL NLFKSIWNNR WLRTISVILF LNKQDLLAEK 300
  301 VLAGKSKIED YFPEFARYTT PEDATPEPGE DPRVTRAKYF IRDEFLRIST ASGDGRHYCY 360
  361 PHFTCAVDTE NIRRVFNDCR DIIQRMHLRQ YELL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle