Protein Overview: 5HT3A_RAT

General Information:
Name(s) found:	5HT3A_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|139947611\|ref\|NP_077370.2\| 5-hydroxytryptamine (serotonin) receptor 3a [Rattus norvegicus] [NCBI NR] gi\|1168223\|sp\|P35563.2\|5HT3A_RAT RecName: Full=5-hydroxytryptamine receptor 3A; AltName: Full=5-HT3R; AltName: Full=5-HT3A; AltName: Full=5-HT-3; AltName: Full=Serotonin receptor 3A; AltName: Full=Serotonin-gated ion channel receptor; Flags: Precursor [NCBI NR] (P35563) 5-hydroxytryptamine 3 receptor precursor (5-HT-3) (Serotonin-gated ion channel receptor) (5-HT3R) [Swiss-Prot] 5-hydroxytryptamine 3 receptor precursor - Rattus norvegicus (Rat) [Swiss-Prot] 5-hydroxytryptamine receptor 3A OS=Rattus norvegicus GN=Htr3a PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):8-50449951;8-50449951 5-hydroxytryptamine 3 receptor precursor [hmr_yeast5_DM3-1_pombe.fasta] 5-hydroxytryptamine 3 receptor precursor (5-HT-3) (Serotonin-gated ion channel receptor) (5-HT3R)gi\|681916\|dbj\|BAA08388.1\| serotonin 5-HT3 receptor [Rattus rattus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 5-hydroxytryptamine 3 receptor precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] 5-hydroxytryptamine (serotonin) receptor 3a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 5-hydroxytryptamine receptor 3A precursor (5-HT3R) (5-HT3A) (5-HT-3) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 5-HYDROXYTRYPTAMINE 3 RECEPTOR PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] 5-hydroxytryptamine 3 receptor precursor (5-HT-3) (Serotonin-gated ion channel receptor) (5-HT3R) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Htr3a 5-hydroxytryptamine receptor 3A [rat-ipi-250309-contam.fasta] 5-hydroxytryptamine receptor 3A precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] 5-hydroxytryptamine receptor 3A OS=Rattus norvegicus GN=Htr3a [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	483 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [TAS] cytoplasm [IDA] postsynaptic membrane [IEA] cell junction [IEA] neuronal cell body [IDA] synapse [IEA] plasma membrane [IDA] axon [IDA]
Biological Process:	ion transport [IEA] cellular response to growth factor stimulus [IEP] response to cocaine [IEP] synaptic transmission [TAS]
Molecular Function:	serotonin binding [UNKNOWN] ion channel activity [IEA] voltage-gated potassium channel activity [IDA] extracellular ligand-gated ion channel activity [IEA] serotonin-activated cation-selective channel activity [IDA] receptor activity [IEA] serotonin receptor activity [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLCIPQVLL ALFLSVLIAQ GEGSRRRATQ AHSTTQPALL RLSDHLLANY KKGVRPVRDW  60
   61 RKPTLVSIDV IMYAILNVDE KNQVLTTYIW YRQFWTDEFL QWTPEDFDNV TKLSIPTDSI 120
  121 WVPDILINEF VDVGKSPSIP YVYVHHQGEV QNYKPLQLVT ACSLDIYNFP FDVQNCSLTF 180
  181 TSWLHTIQDI NISLWRTPEE VRSDKSIFIN QGEWELLGVF TKFQEFSIET SNSYAEMKFY 240
  241 VVIRRRPLFY AVSLLLPSIF LMVVDIVGFC LPPDSGERVS FKITLLLGYS VFLIIVSDTL 300
  301 PATAIGTPLI GVYFVVCMAL LVISLAETIF IVQLVHKQDL QRPVPDWLRH LVLDRIAWLL 360
  361 CLGEQPMAHR PPATFQANKT DDCSAMGNHC SHVGSPQDLE KTSRSRDSPL PPPREASLAV 420
  421 RGLLQELSSI RHSLEKRDEM REVARDWLRV GYVLDRLLFR IYLLAVLAYS ITLVTLWSIW 480
  481 HYS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: 5HT3A_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: